Clinical trials: Infarction
Coronary Artery Disease
Myocardial Injury After Elective Coronary Stenting
This pilot study aims to identify patients at moderate to high risk for peri-procedural (type 4) myocardial infarction or injury after after undergoing an elective coronary intervention (PCI) as measured by high sensitivity…
- Trial name
- NCT01986621
- Where
- Germany
- Volunteers
- 530 people
- Sponsor
- University Hospital Heidelberg
Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication
Efficacy and Clinical Outcomes of Levosimendan in E-CPR
Treatment of refractory cardiac arrest requiring cardiopulmonary resuscitation (CPR) may be augmented with Extracorporeal membrane oxygenation (ECMO) to re-establish perfusion in the absence of return of spontaneous circulation.
- Trial name
- ECPR (NCT05730907)
- Testing
- Levosimendan
- Where
- Qatar
- Volunteers
- 100 people
- Sponsor
- Hamad Medical Corporation
Anterior Wall Acute Myocardial Infarction
Evaluation of Intracoronary Hyperoxemic Oxygen Therapy in Anterior Acute Myocardial Infarction Patients (IC-HOT)
The primary objective of the study is to collect confirmatory data supporting the safety and effectiveness of SSO2 Therapy in treatment of anterior acute myocardial infarction (AMI) patients who have undergone successful…
- Trial name
- IC-HOT (NCT02603835)
- Testing
- SSO2 Therapy
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- TherOx
Biofeedback, Rehabilitation
Effects of Myoelectric Biofeedback on Upper Limb Function in Post-stroke Patients
The purpose of this clinical trial is to investigate the effect of myoelectric biofeedback therapy on upper limb function in elderly patients with cerebral infarction, and to analyze the adjustment of stroke condition and quality…
- Conditions
- Biofeedback, Rehabilitation, Cerebral Infarction
- Trial name
- NCT06443008
- Testing
- Observation Group
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Acute Myocardial Infarction
Sex Differences in Relative Survival and Excess Mortality Following Acute Myocardial Infarction
The aim of this study was to estimate the impact of sex on relative survival and excess mortality following acute myocardial infarction (AMI) using a population-based cohort within a relative survival framework.
- Trial name
- NCT02952417
- Testing
- Excess mortality
- Volunteers
- 180,000 people
- Sponsor
- University of Leeds
HIV, Cardiovascular Diseases
Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults
People with HIV are at risk for cardiovascular disease (CVD). This study evaluated the use of pitavastatin to reduce the risk of CVD in adults with HIV on antiretroviral therapy (ART).
- Trial name
- REPRIEVE (NCT02344290)
- Testing
- Pitavastatin
- Where
- 137 sites in United States, Botswana and 11 more
- Volunteers
- 7,769 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
ST-Elevation Myocardial Infarction, Primary Percutaneous Coronary Intervention
Bivalirudin/Prasugrel Versus Abciximab/Clopidogrel in Patients Presenting With STEMI
In the setting of ST elevation myocardial infarction newer therapies has been recently studied and, following encouraging results, introduced into the clinical practice.
- Trial name
- NCT01158846
- Testing
- prasugrel/bivalirudin, clopidogrel/abciximab
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
ST-Elevation Myocardial Infarction (STEMI), Heart Failure With Preserved Ejection Fraction (HFpEF)
Platelet Derived Growth Factor Receptor ß (PDGFRß) Imaging in Cardiac Fibrosis
An observational, cross-sectional, longitudinal, microdosing Position Emission Tomography (PET) imaging study to investigate platelet derived growth factor receptor beta (PDGFRß) expression in the heart of patients with high or…
- Trial name
- PARIS (NCT06956560)
- Testing
- PET/MRI or separate PET/CT and MRI
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Heart Diseases
Evaluation of CCR2 in Patients Post Myocardial Infarction
To determine the feasibility of 64Cu-DOTA-ECL1i, an investigational PET imaging drug, at the cellular level in the myocardium for individuals who have suffered a heart attack or who have other inflammatory heart disease.
- Trial name
- NCT05107596
- Testing
- 64Cu-DOTA-ECL1i
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA)
Pilot Study to Determine the Optimal Protocol for Preoperative Transcutaneous Vagal Neurostimulation
Post-operative atrial fibrillation (POAF) is a frequent complication of surgical aortic valve replacement, affecting 38 to 63% of patients, and increasing risks of stroke, heart failure, and long-term mortality.
- Conditions
- Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA), Heart Failure, Myocardial Infarction (MI)
- Trial name
- VAGASTIMA-PILT (NCT07891390)
- Testing
- tVNS session on the left earlobe
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ST Elevation Myocardial Infarction, HF - Heart Failure
Diagnostic Values of Galectin-3, Soluble ST2 and BNP in Predicting the Clinical Outcome of ST-Segment Elevation Myocardial Infarction Patients
An acute ST-elevation myocardial infarction occurs due to occlusion of one or more coronary arteries, causing transmural myocardial ischemia which in turn results in myocardial injury or necrosis.
- Conditions
- ST Elevation Myocardial Infarction, HF - Heart Failure, Stable Angina
- Trial name
- NCT05246215
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Myocardial Infarction
Clinical Trails of Photoelectrochemical Immunosensor for Early Diagnosis of Acute Myocardial Infarction
The aim of this prospective randomized controlled clinical trial will evaluate the sensitivity, precision and effectiveness of photoelectrochemical immunosensor for early diagosis of acute myocardial infarction.
- Trial name
- NCT04390490
- Testing
- Graphene quantum dots combined with Si nanowire photoelectrochemical immunosensor
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Bin He
Myocardial Infarction, Vascular Stiffness
Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction
Risk assessment after myocardial infarction is critical in daily practice and evolution toward heart failure especially diastolic heart failure remains a key issue.
- Conditions
- Myocardial Infarction, Vascular Stiffness, Heart Failure
- Trial name
- RIGID-MI (NCT04058782)
- Testing
- Imaging evaluation for vascular assessment
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Lille
ST-segment Elevation Myocardial Infarction (STEMI)
Evaluate Early Invasive Strategy for Patients With STEMI Presenting 24-48 Hours From Symptom Onset
The primary objective of the trial is to evaluate the efficacy of early invasive strategy for STEMI patients within 24-48h of symptom onset.
- Trial name
- NCT04962178
- Testing
- Primary PCI, Optimal medical therapy with primary PCI not performed
- Where
- China
- Volunteers
- 366 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Artery Disease, Coronary Artery Bypass Grafting
TOP-CABG Trial: Follow-up Extension (TOP-CABG FE)
To further evaluate the long-term effects of the two antiplatelet strategies on saphenous vein graft patency, long-term adverse cardiovascular events, and bleeding events after coronary artery bypass grafting (CABG), we plan to…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Dual Antiplatelet Therapy, Bleeding
- Trial name
- NCT07871591
- Volunteers
- 2,290 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cardiovascular Diseases, Heart Diseases
The North Kynouria Project
The North Kynouria Project was initiated to study cardiovascular/stroke risk factors by employing mass screening and long-term surveillance of an adult population in the municipality of North Kynouria, in the county of Arcadia…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Disease, Coronary Disease
- Trial name
- NCT06115213
- Testing
- Patient counselling
- Where
- Greece
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Hemodynamic Parameters, Fatigue
Effect of Isometric Exercise Versus Hand Reflexology on Hemodynamic Parameters Among Patients With AMI
The goal of this clinical trial is to evaluate the comparative effect of isometric exercise versus hand reflexology on primary hemodynamic parameters, fatigue, and anxiety in patients with acute myocardial infarction.
- Conditions
- Hemodynamic Parameters, Fatigue, Anxiety
- Trial name
- NCT07109960
- Testing
- Isometric exercise and hand reflexology
- Where
- Iraq
- Volunteers
- 136 people
- Sponsor
- University of Baghdad
Respiratory Virus Infection, Stroke
Respiratory Virus Infections in Acutely Hospitalized Adult Patients With Pulmonary and Extrapulmonary Complications
Respiratory virus infections are one of the major causes of hospitalizations, and outbreaks of respiratory virus infection have led to severe economic loss.
- Conditions
- Respiratory Virus Infection, Stroke, Lung Disease, Acute Coronary Syndrome
- Trial name
- NCT03816059
- Testing
- Respiratory virus testing
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Cardiogenic Shock
Personalisation of Mean Arterial Pressure in Adult Patients With Cardiogenic Shock
Cardiogenic shock is a life-threatening condition characterized by inadequate cardiac output, leading to organ hypoperfusion and high mortality.
- Trial name
- CARDIOPAM (NCT07345559)
- Testing
- Personalized MAP, Standard MAP
- Where
- 11 sites in France
- Volunteers
- 406 people
- Sponsor
- CMC Ambroise Paré
ST Segment Elevation Myocardial Infarction, Myocardial Oedema
Myocardial Oedema in ST Segment Elevation Myocardial Infarction Myocardial
Cardiac magnetic resonance imaging (CMR) is a non invasive technique used to obtain functional and anatomical information on the heart.
- Trial name
- NCT01897350
- Testing
- Cardiac magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Elisa McAlindon