Clinical trials: Infected Surgical Wound
Rectal Cancer, Organ-Space Surgical Site Infection
Concordance Between Monitoring Systems for Organ/Space Surgical Site Infections in Rectal Surgery
The Catalan Cancer Plan (CCP) undertakes periodic audits of cancer treatment outcomes, including organ/space surgical site infections (O/S-SSI) rates, while the Catalan Healthcare-associated Infections Surveillance Programme…
- Trial name
- NCT06104579
- Testing
- Person-level linkage of both databases looking for concordance in the diagnosis of organ-space surgical site infection
- Where
- Spain
- Volunteers
- 11,367 people
- Sponsor
- Hospital de Granollers
Postoperative Complications, Surgical Site Infection
Hierarchy of Effects of Laboratory Markers and Their Interaction With Comorbidity Concerning Outcome and Personalized Treatment of Trauma Patients in Emergency Care and Rehabilitation
At least ten percent of trauma patients suffer from any sort of complication. The study aims to identify a risk factor profile to early identify trauma patients at risk.
- Conditions
- Postoperative Complications, Surgical Site Infection, Wound Infection, Non-healing Wound
- Trial name
- HELICOPTER (NCT06758427)
- Where
- Germany
- Volunteers
- 2,300 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Surgical Site Infections
Effect of Mupirocin Dressings Versus Island Dressings on Surgical Site Infections in Elective Colorectal Surgery
Infections at the site of surgical incisions (SSIs) are the most common infection among surgical patients. Although all patients undergoing surgical procedures are at risk for developing SSIs, colorectal surgery has had…
- Trial name
- NCT02619773
- Testing
- mupirocin ointment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Infection Prophylaxis in Colo Rectal Surgery
Orally Administered Trimethoprim-sulfamethoxazole and Metronidazole as Prophylaxis of Infection Following Elective Colorectal Surgery
The current standard Swedish infection prophylaxis in colorectal surgery is intravenously administered cefuroxime and metronidazole. this combination is well studied.
- Trial name
- NCT00613769
- Testing
- trimethoprim-sulfamethoxazole + metronidazole, cefuroxime and metronidazole
- Where
- 6 sites in Sweden
- Volunteers
- 1,073 people
- Sponsor
- Halmstad County Hospital
Postoperative Wound Infection
Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation
Surgical site infections (SSI) constitute a significant health-economic and clinical challenge. The investigators conducted a cluster-randomized, cross-over study to compare the efficacy of plain soap and water (PSW), used…
- Trial name
- NCT00987402
- Testing
- Plain soap and water (PSW), Alcohol-based hand rub (ABHR)
- Where
- Kenya
- Volunteers
- 3,317 people
- Sponsor
- University Hospital, Geneva
Surgical Site Infection (SSI), Emergency Laparotomies
The Spotlight Study: Early Identification of Post-Surgical Infections Using Bedside Ultrasound.
Introduction: The goal of this observational study is to learn whether point-of-care ultrasound (POCUS) can help detect early fluid build-up under the skin after open abdominal surgery (laparotomy) and whether these findings can…
- Conditions
- Surgical Site Infection (SSI), Emergency Laparotomies, Point of Care Ultrasound (POCUS)
- Trial name
- SPOTLIGHT (NCT07549880)
- Testing
- Point-of-Care Ultrasound (POCUS), Microbiological Wound Swab, ASEPSIS Wound Assessment
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Slagelse Hospital
Surgical Wound Infection
Supplemental Postoperative Oxygen and Wound Infection in Morbidly Obese Patients
The investigators propose to test the hypothesis that the incidence of major complications related to infection or inadequate healing is reduced in morbidly obese patients given 80% inspired oxygen during, and for 12-18 hours…
- Trial name
- NCT00315822
- Testing
- 80% oxygen, 30% oxygen
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- The Cleveland Clinic
Surgical Site Infection, Antibiotic Resistant Infection
Antibiotic Stewardship Program in Pancreatic Surgery: a Multicenter Time Series Analysis (BIOSTEPS).
Rationale: Surgical site infection (SSI) is one of the most frequently reported postoperative complication, occurring in up to one-third of patients.
- Trial name
- BIOSTEPS (NCT04199494)
- Testing
- Antibiotic Stewardship Program
- Where
- 2 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Surgical Site Infection
Detection of Staph Colonization in Pre-op Arthroplasty Patients
This study will evaluate which body site(s) provide the best source of possible staph presence in participants undergoing total joint arthroplasty.
- Trial name
- Staph (NCT01648088)
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Skin Transplantation, Skin Grafting
Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour Excision
The goal of this clinical trial is to compare the effect of negative pressure wound therapy (NPWT) versus traditional dressings on the incidence of transplant infection in adult patients undergoing split-thickness skin grafting…
- Conditions
- Skin Transplantation, Skin Grafting, Split Thickness Skin Graft, Negative-Pressure Wound Therapy
- Trial name
- LEGS (NCT07040683)
- Testing
- Negative Pressure Wound Therapy (NPWT), Traditional Dressing
- Where
- Sweden
- Volunteers
- 232 people
- Sponsor
- Region Skane
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital