Clinical trials: Infected Wound
Wound Infection, Wound Surgical
Efficacy of Negative Pressure Wound Closure Therapy by PICO System in Prevention of Complications of Femoral Artery Exposure
Evaluate negative pressure wound closure therapy by PICO system in Prevention of complications of femoral artery exposure.
- Trial name
- NCT04453319
- Testing
- Femoral Wound Closure and dressing
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Microbial Contamination, Environmental Contamination
Vacuum-Assisted Clipper in Preoperative Hair Removal: Effects on Contamination and Skin Integrity
This randomized controlled study aims to evaluate the effectiveness of a vacuum-assisted electric trimmer (VD-ETM) compared with a standard electric trimmer (ETM) for preoperative hair removal.
- Trial name
- NCT07517341
- Testing
- Vacuum-Assisted Electric Shaver (VD-ETM) Method
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Surgical Site Infection
Preventing Surgical Site Infection by Using Prophylactic Occlusive Ionic Silver-containing Dressing
Background: Ionic silver-containing dressing has been proven as a broad spectrum antimicrobial agent to reduce inflammation of wounds and promote healing.
- Trial name
- NCT03380169
- Testing
- Prophylactic advance wound dressing, Prophylactic conventional wound dressing
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Princess Margaret Hospital, Hong Kong
Postoperative Infection, Geriatrics
Elderly Patients Surgical Site Infection Phenotypes Identification
This study utilizes Latent Class Analysis (LCA) to identify phenotypes of Surgical Site Infection (SSI) in elderly patients following non-cardiac surgery.
- Conditions
- Postoperative Infection, Geriatrics, Prediction, Surgical Site Infection
- Trial name
- NCT06612177
- Where
- China
- Volunteers
- 42,532 people, healthy volunteers welcome
- Sponsor
- Weidong Mi
Surgical Site Infection
WHO Checklist- Based Infection Prevention Guidelines in Mulago Hospital
This prospective cohort study will assess all mothers undergoing elective and emergency caesarean delivery in the labour ward theatre at Mulago National Referral Hospital based temporarily at Kawempe Hospital.
- Trial name
- NCT03822039
- Where
- Uganda
- Volunteers
- 768 people
- Sponsor
- Makerere University
Wound Infection
Evaluation of Phage Therapy for the Treatment of Escherichia Coli and Pseudomonas Aeruginosa Wound Infections in Burned Patients
The objective of PHAGOBURN is to assess tolerance and efficacy of local bacteriophage treatment of E. coli or P. aeruginosa wound infections in burned patients.
- Trial name
- PHAGOBURN (NCT02116010)
- Testing
- E. coli Phages cocktail, Standard of care : Silver Sulfadiazine, P. Aeruginosa, Phages cocktail
- Where
- 5 sites in Belgium, France and 1 more
- Sponsor
- Phagenix
Surgical Wound Infection
Closed Incision Negative Pressure Wound Therapy for the Prevention of Surgical Site Infections in Abdominal Surgery
Surgical site infections (SSI) are a frequent complication in abdominal surgery. SSI lead to worse outcomes for the affected patients and significantly higher healthcare costs.
- Trial name
- CISSI (NCT06068517)
- Testing
- Closed incision negative pressure wound therapy, Standard dressing
- Where
- Switzerland
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Surgical Wound Infection, Infection; Cesarean Section
Incisional Negative Pressure Wound Therapy for Prevention of Postoperative Infections Following Caesarean Section
The purpose of this study is to examine whether obese women (BMI >= 30) who give birth by caesarean section have a reduced incidence of wound infection and dehiscence when incisional Negative Pressure Wound Therapy is applied…
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Cesarean Section; Dehiscence, Complications; Cesarean Section
- Trial name
- NCT01890720
- Testing
- iNPWT, Standard postoperative wound dressing
- Where
- 5 sites in Denmark
- Volunteers
- 876 people
- Sponsor
- Odense University Hospital
Surgical Site Infection, Antibiotic Prophylaxis
The Role of Guideline-adherent Perioperative Antibiotic Administration and the Risk of Surgical Site Infections After Non-cardiac Surgery.
This study will seek to describe current practice of antibiotic prophylaxis to identify the effect of appropriate perioperative antimicrobial coverage - specifically regarding timing, dose adjustments, and redosing - on surgical…
- Trial name
- NCT03982810
- Testing
- Antibiotics
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Surgical Wound Infection, Cesarean Section
Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial
The Prophylactic Negative Pressure Wound Therapy in Obese Women at Cesarean Trial is a large pragmatic multi-center randomized clinical trial designed to evaluate the effectiveness, safety and cost-effectiveness of prophylactic…
- Trial name
- Prevena-C (NCT03009110)
- Testing
- Prophylactic NPWT, Standard Dressing
- Where
- 6 sites in United States
- Volunteers
- 1,624 people, healthy volunteers welcome
- Sponsor
- Indiana University
Ulcer Foot, Ulcer Healing
Aquacel With Strengthening Fiber (WSF) Ribbon Dressings
Retrospective, multi-site, non-comparative, post-market study
- Conditions
- Ulcer Foot, Ulcer Healing, Wound Infection
- Trial name
- NCT07308665
- Testing
- Aquacel Ribbon
- Volunteers
- 214 people
- Sponsor
- ConvaTec Inc.
Surgical Wound Infection
Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis
Routine antibiotics for the intravenous and oral prophylaxis of colorectal surgery will be used. Experimental group: Patients undergoing elective colorectal surgery that involves, colonic resection.
- Trial name
- ORALEV (NCT02505581)
- Testing
- Extra dosage - cefuroxime (750mg) I.V, Colorectal Surgery, Ciprofloxacin 750 mg oral
- Where
- 3 sites in Spain
- Volunteers
- 536 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Lower Extremity Wound Infected, Venous Stasis Ulcers
V.A.C. VeraFlo™ Instillation Therapy vs V.A.C. Ulta™ Therapy on Biofilm in Chronically Infected Wounds
This study would like to determine if using negative pressure wound therapy with an instillation of .125% Dakins is more effective than using negative pressure wound therapy alone on biofilm removal, disruption and elimination in…
- Trial name
- NCT02009501
- Testing
- VAC VeraFlo with Dakins Instillation, VAC Ulta Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Surgical Wound Infection, Vascular Surgery
Supplemental Oxygen in Vascular Surgery
The purpose of this study was to test the hypothesis that supplemental postoperative oxygen reduces the risk of surgical wound infection in patients following lower limb vascular surgery.
- Trial name
- NCT00873704
- Testing
- supplemental postoperative oxygen
- Where
- 6 sites in Finland
- Volunteers
- 274 people
- Sponsor
- North Karelia Central Hospital
Major Puerperal Infection, Postpartum, Wound Complications
Negative Pressure Wound Therapy After Cesarean Delivery
This study is aimed at determining whether or not the use of a wound suction device placed on the cesarean incision instead of a standard sterile dressing will decrease the prevalence of wound complications and wound infections…
- Conditions
- Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation
- Trial name
- NCT01637870
- Testing
- Prevena negative pressure wound system
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Abbey Hardy-Fairbanks
Surgical Wound Infection
Recolonization Following Preoperative Disinfection Plastic Adhesive Drapes
The purpose of this study is to measure the time to recolonization intraoperatively after preoperative disinfection with chlorhexidine solution in ethanol and to determine evidence of differential bacterial growth with or without…
- Trial name
- NCT01316588
- Testing
- Plastic adesive drape, Microbial Sealant
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Örebro University, Sweden
Surgical Site Infection, Patient Satisfaction
Effect of Surgical Site Infections on Patient Reported Cosmetic Outcomes in Dermatologic Surgery
This study involves surveying two matched groups of patients that underwent dermatologic surgery at our department. One group had a documented surgical site infection and the other didn't.
- Trial name
- NCT04744961
- Testing
- SCAR-Q survey
- Where
- Sweden
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Region Skane
Post Operative Wound Infection, Suture
No Closure vs Interrupted vs Continuous Subcutaneous Closure: Operative Time and Wound Outcomes
The goal of this clinical trial is to research whether different methods of suturing during elective cesarean delivery affect surgery time and early wound healing.
- Conditions
- Post Operative Wound Infection, Suture, Suture Techniques, Ceserean Section
- Trial name
- NCT07451275
- Testing
- Suture technique, Interrupted closure (3 sutures), Suture technique, Continuous non-locking closure
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Yuzuncu Yil University
Surgical Wound Infection
Prevention of Surgical Site Infections
The primary research question is whether interventions to prevent caregiver and system errors will increase the proportion of laparotomy patients who receive recommended measures to prevent surgical site infections.
- Trial name
- NCT00353613
- Testing
- Package of targeted interventions to reduce error
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- The University of Texas Health Science Center, Houston
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