Clinical trials: Infected Wound
Wound
Staples Versus Suture for Cesarean Wound Closure
The objective of this randomized controlled trial is to compare wound morbidity (including disruption and infection) in surgical staples versus absorbable subcuticular suture for wound closure in cesarean deliveries.
- Trial name
- SVS (NCT01008449)
- Testing
- Surgical staples, Absorbable Surgical Suture
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of Alabama at Birmingham
Staphylococcal Aureus Infection, Surgical Site Infection (SSI)
Gene Expression Analysis of Biofilm Formation and Antimicrobial Resistance in Clinical Methicillin-Resistant Staphylococcus Aureus
Staphylococcus aureus are Gram-positive cocci that asymptomatically colonize the skin and mucosal surfaces of approximately 20-30% of healthy individuals . Although they commonly exist as a harmless commensal organisms, S.
- Trial name
- NCT07796555
- Testing
- swab from lesion, Biochemical reactions, Antibiotic sensitivity
- Volunteers
- 100 people
- Sponsor
- Sohag University
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- PHOMIC (NCT04067843)
- Testing
- Photodynamic treatment
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypothermia, Hemorrhage, Postpartum
Complications Associated With Intraoperative Hypothermia.
Maintaining intraoperative normothermia and temperature measurement is a marker of quality of care. We know that intraoperative hypothermia is associated with an increased risk of cardiovascular events, infection of the surgical…
- Conditions
- Hypothermia, Hemorrhage, Postpartum, Infection Surgical Wound, Transfusion-dependent Anemia
- Trial name
- NCT05203016
- Testing
- Hipotermia/Normotermia
- Where
- Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Operation Wound; Infection, Bacterial Infections
Nudging Effect of Timer on Surgical Rub
To study whether a device has a nudging effect on the time spend on surgical rub.
- Conditions
- Operation Wound; Infection, Bacterial Infections, Surgical Procedure, Unspecified
- Trial name
- NCT04609384
- Testing
- Alcohol rub timer device
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Sygehus Lillebaelt
Surgery, Surgical Site Infection
Intraoperative Hygiene Measures and Surgical Site Infections
Surgical site infections are associated with high morbidity and cost Hypothesis: Extended intraoperative hygiene measures decrease surgical site infections in general surgery compared to standard hygiene measures.
- Conditions
- Surgery, Surgical Site Infection, Hygiene, Discipline
- Trial name
- NCT00555815
- Where
- Switzerland
- Volunteers
- 1,032 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Complications
The Effect of Telephone Nursing Education and Counseling Services Given to Satisfaction Level and Self-Care Strength
In the post-discharge period, it is important to follow the patients from home by telephone and to provide the necessary nursing education and counseling services, increasing the self-care powers of the patients, increasing their…
- Trial name
- NCT05487638
- Testing
- Nursing Education and Counseling Service Provided to Patients by Video Calling on the Phone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Ankle Fractures
Cryotherapy Reduces Time to Surgery and Local Complication in Patients With Ankle Fractures
Ankle fractures are common injuries and cryotherapy is routinely used to reduce pain, swelling and local skin complications, both before and after surgery. However, the results on ankle surgery are contradictory.
- Trial name
- Cryotherapy (NCT06396364)
- Testing
- Cryotherapy
- Where
- 2 sites in Italy
- Volunteers
- 169 people
- Sponsor
- Azienda Ospedaliera San Camillo Forlanini
Surgical Wound Infection, Hematoma
Comparing Outcomes Of Single Layer Versus Multilayer Leg Closure Techniques Following Great Saphenous Vein Harvesting For CABG
This study aims to address the knowledge gap by comparing the outcomes of single-layer and multi-layer leg closure techniques following great saphenous vein harvesting for Coronary artery bypass grafting. Research question: 1.
- Conditions
- Surgical Wound Infection, Hematoma, Seroma Following Procedure, Prolonged Hospital Stay
- Trial name
- CABG (NCT07355452)
- Testing
- Multi-layer closure (MLC), singlelayer closure for leg wound
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Tibia Fracture
Infection Rates Following Internal Fixation of Open and Closed Tibia Fractures in India
The objectives of this study are to investigate infection rates and management for open and closed tibia fracture subjects in India treated with internal fixation.
- Trial name
- NCT01691599
- Where
- 11 sites in India
- Volunteers
- 800 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Complicated Skin and Soft Tissue Infection
Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections.
The purpose of this study is to evaluate the effects of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in treatment of patients with complicated bacterial skin and soft tissue infections.
- Trial name
- NCT02202135
- Testing
- Ceftaroline fosamil, Vancomycin, Aztreonam
- Where
- 22 sites in Argentina, Brazil and 11 more
- Volunteers
- 4 people
- Sponsor
- Pfizer
Surgical Wound Infection
Surgical Site Infections at a West Cameroon Hospital
Surgical site infections (SSI) constitute an important health concern in low and middle income countries, leading to prolonged hospital stay and increased costs.
- Trial name
- SSI Mbouo (NCT05018884)
- Testing
- Observation of surgical site infections
- Where
- Cameroon
- Volunteers
- 148 people
- Sponsor
- Christian Doll
Wound Infection
Prevention of Gastrostomy-Related Wound Infection by Vancomycin in Carriers of Methicillin-Resistant Staphylococcus Aureus.
The aim of this study is to determine whether vancomycin with cefazoline is superior to vancomycin with placebo in preventing gastrostomy-related wound infection in carriers of methicillin-resistant staphylococcus aureus (MRSA).
- Trial name
- NCT00150852
- Testing
- Vancomycin
- Where
- 3 sites in France, Switzerland
- Volunteers
- 96 people
- Sponsor
- University Hospital, Geneva
Postoperative Hernia
Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR)
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Trial name
- (PROTOP-PAR) (NCT05508152)
- Testing
- Wound irrigation with amoxicillin-clavulanate in saline solution, Wound irrigation with a saline solution
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital de Granollers
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Colorectal Cancer, Lung Cancer
The Effects of Preoperative Bevacizumab on Perioperative Complications
This is a nationwide multicenter,retrospective,observational real-world study. 1. To assess the risk of perioperative complications in patients with tumor who received bevacizumab prior to unexpected operation. 2.
- Conditions
- Colorectal Cancer, Lung Cancer, Operation Wound; Infection, Bevacizumab
- Trial name
- NCT04788381
- Testing
- Bevacizumab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Edematous, Synovitis
Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements
This research study is being conducted to determine if taking oral (by mouth in pill form) Apatone®B (a combination of Vitamins C and K3) will reduce chronic joint discomfort and improve function of non-infected symptomatic…
- Conditions
- Edematous, Synovitis, Foreign Body Reaction, Osteolysis
- Trial name
- Apatone-B (NCT01272830)
- Testing
- Apatone®B
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- IC-MedTech Corporation
Surgical Infection, Cesarean Section Wound
Evaluation of Surgical Site Infection After Cesarean Section
This study aims to investigate surgical site monitoring after cesarean section using a mobile application currently being developed.
- Trial name
- NCT07205939
- Testing
- Mobile Application usage
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sibel Bulut Haklı
Infection, Surgical Site Infection
Changing of Dressing for Periprosthetic Joint Infection in Total Knee Arthroplasty
The primary aim of the study is to compare two methods for a relationship with total knee infection: regular changing of dressings and not changing dressings.
- Conditions
- Infection, Surgical Site Infection, Prosthetic Infection, Wound Infection
- Trial name
- NCT04346875
- Testing
- Regularly changing of dressing, No application
- Volunteers
- 842 people
- Sponsor
- Bezmialem Vakif University
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