Clinical trials: Infected Wound
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections
Postpartum infection if a major cause of maternal morbidity and mortality and surgical site infections are some of the common complications following cesarean section.
- Conditions
- Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
- Trial name
- NCT05392400
- Testing
- Steri3X, Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Surgical Site Infection
Wound Antiseptic Study With Hypochlorous Acid & Iodopovidone
The purpose of this study is to determine whether hypochlorous acid is an effective antiseptic agent to prevent surgical site infection.
- Trial name
- WASH (NCT00692757)
- Testing
- Hypochlorous acid, Iodopovidone
- Where
- Colombia
- Volunteers
- 432 people
- Sponsor
- Universidad Tecnológica de Pereira
Colorectal Surgery
Mechanical Bowel Prep Randomized Study
Following colon surgery, surgical site infection (SSI) is the most common complication and leads to longer recovery time for patients and increased health care costs.
- Trial name
- NCT04931173
- Testing
- IVA+OA versus IVA+MBP+OA
- Volunteers
- 1,062 people
- Sponsor
- Mount Sinai Hospital, Canada
Liver Transplantation, Surgical Wound Infection
Glycemic Control and Surgical Site Infection Incidence Among Liver Transplantation Recipients
Context: The hyperglycemia is an important independent risk factor for the Surgical Site Infection (SSI) development among liver transplantation recipients.
- Trial name
- NCT03474666
- Testing
- Strict Glycemic Control Group, Standard Glycemic Control Group
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- Ramon Oliveira
Microbial Contamination, Environmental Contamination
Vacuum-Assisted Clipper in Preoperative Hair Removal: Effects on Contamination and Skin Integrity
This randomized controlled study aims to evaluate the effectiveness of a vacuum-assisted electric trimmer (VD-ETM) compared with a standard electric trimmer (ETM) for preoperative hair removal.
- Trial name
- NCT07517341
- Testing
- Vacuum-Assisted Electric Shaver (VD-ETM) Method
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Surgical Site Infection
INtestinal Dysbiosis and TRanslocation of Bacteria in Patients Undergoing Surgery
The goal of this observational study is to contribute to a better understanding of the perioperative kinetics of intestinal microbial composition and association with surgical site infections.
- Trial name
- INTRA (NCT05775341)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cellulitis, Wound Infection
Penicillin for the Emergency Department Outpatient Treatment of CELLulitis
The main objective of this study is to investigate the non-inferiority of oral flucloxacillin alone compared with a combination of oral flucloxacillin and phenoxymethylpenicillin for the emergency department directed outpatient…
- Conditions
- Cellulitis, Wound Infection, Abscess
- Trial name
- PEDOCELL (NCT02922686)
- Testing
- Flucloxacillin, Phenoxymethylpenicillin
- Where
- 5 sites in Ireland
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Coronary Artery Disease, Coronary Artery Bypass Grafting
Comparative Outcomes of Mammary Artery Harvesting: Infection, Occlusion Rates and Thoracic Pain Assessment
The COMFORT Trial is a randomized controlled superiority trial comparing skeletonized (SK) versus non-skeletonized (non-SK) harvesting of the left internal mammary artery (LIMA) to left anterior descending artery (LAD) graft in…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Surgical Site Infection
- Trial name
- COMFORT (NCT07720661)
- Testing
- Skeletonized LIMA Harvesting, Non-Skeletonized LIMA Harvesting
- Sponsor
- Hamilton Health Sciences Corporation
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Wound Infections
Cubicin(R) for Complicated Post-surgical Wound Infections
The purpose of the study is to describe the clinical efficacy of CUBICIN therapy in patients with superficial and deep post-surgical Gram-positive wound infections
- Trial name
- PSW (NCT00651131)
- Testing
- daptomycin
- Volunteers
- 69 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Wound Infection
Use of Insorb Absorbable Vicryl Staples in Skin Closure for Cesarean Section
The purpose of this study is to evaluate the incidence of wound breakdown or wound infection following skin closure with Insorb subcuticular absorbable staples versus metal staples after cesarean section through a retrospective…
- Trial name
- NCT01446627
- Testing
- There is no intervention for this study
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Antibiotic Prophylaxis, Wound Infection
The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
- Conditions
- Antibiotic Prophylaxis, Wound Infection, Groin Hernia
- Trial name
- NCT06576154
- Testing
- Cefazolin 1000 MG
- Where
- Syria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Surgical Wound Infection, Surgical Wound
Redscar © Application for Detection of Infected Surgical Wounds
Surgical site infection (SSI) is the second cause of healthcare-associated infections (HAIs). Its appearance increase mobidity and post-operatice hospital stays, increasing costs aswell, although its one of the most preventable…
- Conditions
- Surgical Wound Infection, Surgical Wound, Surgical Site Infection
- Trial name
- NCT05485233
- Testing
- REDSCAR App
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Son Espases
Superficial Surgical Site Infection
Collagen-Gentamicin Implant in the Treatment of Contaminated Surgical Abdominal Wounds
The investigators' hypothesis is that placement of CollatampG in the subcutaneous layer of contaminated abdominal wounds is effective prophylaxis for superficial surgical site infection (SSI).
- Trial name
- NCT00977405
- Testing
- Collatamp Gentamicin Implant
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Surgical Site Infection, Zonulin
Zonulin Biomarker for Diagnosis of Hip and Knee Infections
Prior studies investigating the etiopathogenesis of surgical site infection (SSI) traditionally suggested three main ways for the infection to occur: local contamination occurring during the surgery, hematogenous translocation of…
- Trial name
- NCT04666519
- Testing
- Zonulin Biomarker
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Wound Complications, Wound Infection
A Study to Evaluate a Quality Improvement Intervention to Reduce Wound Separation Rates in Obese Gynecologic Oncology Service Patients Undergoing Abdominal Surgery
Approximately 500,000 surgical site infections occur annually in the US. These lead to worse patient quality of life, more outpatient and emergency room visits, readmissions and home services, with an estimated increase in costs…
- Conditions
- Wound Complications, Wound Infection, Wound Separation
- Trial name
- NCT02071251
- Testing
- Prospective wound complication protocol
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Washington University School of Medicine
Complication of Surgical Procedure
TCOT Effectiveness in Preventing Wound Infections in Perineal Resections
In colorectal surgery, oxygen insufflation (which leads to higher oxygen concentration in the surgical site) has been shown to decrease infection rate.
- Trial name
- NCT02374294
- Testing
- Epiflo
- Sponsor
- Neogenix, LLC dba Ogenix
COVID, Severe Acute Respiratory Syndrome
LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)
To evaluate the proportion of subjects alive and free of respiratory failure (e.g. need for non-invasive or invasive mechanical ventilation, high flow oxygen, or ECMO) and free of the need for continued renal replacement therapy…
- Conditions
- COVID, Severe Acute Respiratory Syndrome, Sars-CoV2, Acute Kidney Injury
- Trial name
- NCT04402957
- Testing
- LSALT peptide
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 61 people
- Sponsor
- Arch Biopartners Inc.
Cardiac Surgery, Bone Wax, NU-KNIT, Median Sternotomy, Deep Sternal Wound Infection, Surgical Site Infection
Surgicel NU-KNIT Vs Bone Wax on Median Sternotomy
Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
- Trial name
- NBCS (NCT06869772)
- Testing
- Closure of sternotomy
- Where
- Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Surgical Site Infection
PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)
The purpose of this study is to see whether applying povidone iodine (PVI) to the noses of patients undergoing lower extremity (leg, ankle, or foot) orthopedic fixation procedures of high-energy lower extremity fractures (HELEF)…
- Trial name
- POTENT (NCT05763602)
- Testing
- povidone-iodine topical ointment
- Where
- 6 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Loreen Herwaldt
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