Clinical trials: Infected Wound
Staphylococcus Aureus, Staphylococcal Skin Infections
Rapid Test to Detect Staphylococcus Aureus in Blood and Wound Infections
The purpose of this study is to determine whether the Cepheid GeneXpert system accurately detects Methicillin-Resistant and -Susceptible Staphylococcus aureus in blood cultures and wound swabs.
- Conditions
- Staphylococcus Aureus, Staphylococcal Skin Infections, Bacteremia
- Trial name
- NCT01198262
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Wound Infection Rate
Tap Water Versus Normal Saline for Wound Irrigation
This study is designed to compare the infection rates in wounds irrigated with sterile normal saline to those irrigated with chlorinated tap water.
- Trial name
- NCT01564342
- Testing
- wound irrigation with study fluid
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- Stanford University
Surgical Site Infection
Randomized Controlled Trial to Evaluate the Optimal Timing of Surgical Antimicrobial Prophylaxis
Surgical site infections (SSI) are the most frequent hospital acquired infections in patients who underwent surgery. With regards to the increasing financial restraint in patient care, the socio-economic burden of SSI in the…
- Trial name
- NCT01790529
- Testing
- Early administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in anesthetic room (75 to 30 minutes prior to skin incision), Late administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in the operating theatre (within 30 minutes prior to skin incision)
- Where
- Switzerland
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Incisional Hernia, Surgical Site Infection
Prophylactic Mesh Reinforcement for Stoma Closure
In the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection …
- Conditions
- Incisional Hernia, Surgical Site Infection, Postoperative Pain, Hospital Stay, Length of Stay in Hospital From Surgery to Discharge
- Trial name
- OASIS (NCT06157645)
- Testing
- Prolene mesh
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
The Patients Who Receive Percutaneous Endoscopic Gastrostomy, Peristomal Wound Infection After the Operation of PEG
Tailored Antibiotics Prophylaxis for Percutaneous Endoscopic Gastrostomy
Tailored antibiotic prophylaxis according to the individual throat swab culture could reduce the peristomal infection rate
- Conditions
- The Patients Who Receive Percutaneous Endoscopic Gastrostomy, Peristomal Wound Infection After the Operation of PEG, Prophylactic Antibiotics Before PEG
- Trial name
- PEG (NCT01237730)
- Testing
- cefuroxime, Tailored antibiotic
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Cheng Kung University
Operation Wound; Infection, Bacterial Infections
Nudging Effect of Timer on Surgical Rub
To study whether a device has a nudging effect on the time spend on surgical rub.
- Conditions
- Operation Wound; Infection, Bacterial Infections, Surgical Procedure, Unspecified
- Trial name
- NCT04609384
- Testing
- Alcohol rub timer device
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Sygehus Lillebaelt
Hypothermia, Hemorrhage, Postpartum
Complications Associated With Intraoperative Hypothermia.
Maintaining intraoperative normothermia and temperature measurement is a marker of quality of care. We know that intraoperative hypothermia is associated with an increased risk of cardiovascular events, infection of the surgical…
- Conditions
- Hypothermia, Hemorrhage, Postpartum, Infection Surgical Wound, Transfusion-dependent Anemia
- Trial name
- NCT05203016
- Testing
- Hipotermia/Normotermia
- Where
- Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Surgical Wound Infection, Vascular Surgery
Supplemental Oxygen in Vascular Surgery
The purpose of this study was to test the hypothesis that supplemental postoperative oxygen reduces the risk of surgical wound infection in patients following lower limb vascular surgery.
- Trial name
- NCT00873704
- Testing
- supplemental postoperative oxygen
- Where
- 6 sites in Finland
- Volunteers
- 274 people
- Sponsor
- North Karelia Central Hospital
Staphylococcal Aureus Infection, Surgical Site Infection (SSI)
Gene Expression Analysis of Biofilm Formation and Antimicrobial Resistance in Clinical Methicillin-Resistant Staphylococcus Aureus
Staphylococcus aureus are Gram-positive cocci that asymptomatically colonize the skin and mucosal surfaces of approximately 20-30% of healthy individuals . Although they commonly exist as a harmless commensal organisms, S.
- Trial name
- NCT07796555
- Testing
- swab from lesion, Biochemical reactions, Antibiotic sensitivity
- Volunteers
- 100 people
- Sponsor
- Sohag University
Orthopedic Disorders, Surgical Site Infection
Preoperative Decolonization and Surgical Site Infections - a Prospective Randomized Trial
Surgical site infections are a major postoperative complication and are mostly due to colonization with endogenous germs, like Staphylococcus aureus, Staphylococcus epidermidis or Propionibacterium acnes.
- Trial name
- DECO-SSI (NCT02560155)
- Testing
- Mupirocin 2% nasal ointement, Chlorhexidine sol 4%
- Where
- Switzerland
- Volunteers
- 1,300 people
- Sponsor
- Lindenhofgruppe AG
Cesarean Section, Surgical Site Infection
Effect of Betadine Vaginal Cleansing Before Cesarean Section to Reduce Postoperative Infectious Morbidity
This randomized controlled trial aims to evaluate the efficacy of preoperative vaginal cleansing with 5% povidone-iodine in reducing postoperative infectious morbidity among women undergoing cesarean section.
- Conditions
- Cesarean Section, Surgical Site Infection, Endometritis
- Trial name
- NCT07715409
- Testing
- Povidone-iodine 5% solution
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mohamed Mousa Mohamed Mousa
Cardiovascular Disease, Surgical Site Infection
Innovative Sternal Closure Techniques: Evaluating STRATAFIX™ and DERMABOND™ for Reduced Complications in CABG Patients
The goal of this clinical trial is to learn if a new method of closing the breastbone after heart bypass surgery can improve healing and reduce complications in adults undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Cardiovascular Disease, Surgical Site Infection, Superficial Sternal Wound Infection, Mediastinitis
- Trial name
- NCT07507409
- Testing
- Knotless Barbed Sutures, Mesh-based Topical Skin Adhesive
- Volunteers
- 401 people
- Sponsor
- Unity Health Toronto
Carpal Tunnel Syndrome, Wound Infection
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release
Carpal Tunnel Syndrome is a prevalent condition, up to 9% in women and 0.6% in men. Surgical decompression in the most effective treatment. After surgery, approximately 1,8% of the patients develop a wound infection.
- Conditions
- Carpal Tunnel Syndrome, Wound Infection, Suture, Complication
- Trial name
- SENSE (NCT05431101)
- Testing
- Carpal Tunnel Release
- Where
- 2 sites in Netherlands
- Volunteers
- 2,604 people, healthy volunteers welcome
- Sponsor
- Gelre Hospitals
Diabetes Mellitus, Diabetes Complications
Comparison of Resin Salve and Octenidine in Patients With Neuropathic Diabetic Foot Ulcers
Prevalence of diabetic foot ulcers are reported to be 15% in patients who suffer from diabetes and ulcerations are present in 84% of all diabetes-related amputations.
- Conditions
- Diabetes Mellitus, Diabetes Complications, Diabetic Neuropathies, Wound Infection
- Trial name
- NCT02169167
- Testing
- Resin salve treatment, Octenidine treatment
- Where
- Poland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Janne J. Jokinen
Surgical Site Infection
Disposable Versus Reusable DrApes and Gowns for Green OperatiNg Theatres
Multicentre non-inferiority cluster randomised trial testing Disposable versus Reusable drApes and Gowns for green OperatiNg theatres.
- Trial name
- DRAGON (NCT06164444)
- Testing
- Intervention: Reusable drapes and gowns, Comparator: Disposable (single-use) drapes and gowns
- Where
- Mexico
- Volunteers
- 26,800 people
- Sponsor
- University of Birmingham
Acute Lithiasic Cholecystitis Grade I or II, Symptoms Lasting for Less Than 5 Days
Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis
Assess whether postoperative antibiotics after cholecystectomy for acute lithiasic cholecystitis little or moderately severe, is effective and therefore justified.
- Conditions
- Acute Lithiasic Cholecystitis Grade I or II, Symptoms Lasting for Less Than 5 Days, Required Cholecystectomy, Preoperative Amoxicillin Clavulanic Acid for at Most 5 Days
- Trial name
- ABCAL (NCT01015417)
- Testing
- Amoxicillin clavulanic acid, No medication
- Where
- 21 sites in France
- Volunteers
- 414 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Infection Control, Surgical Site Infection
Early Recognition and Response to Increases in Surgical Site Infections Using Optimized Statistical Process Control Charts: The Early 2RIS Study
The purpose of this quality improvement study is to measure the effectiveness of surveillance using optimized statistical process control (SPC) methods and feedback on rates of surgical site infection (SSI) compared to…
- Trial name
- Early 2RIS (NCT03075813)
- Testing
- Intervention Cluster
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Duke University
Acute Non Infected Wounds, Non Infected Post Surgical Wounds
A Prospective, Open, Non-controlled Clinical Investigation to Evaluate a New Negative Pressure Wound Therapy (NPWT) System to be Used in the Treatment of Acute Non-infected Wounds and Post Surgical Infected Wounds
The investigation is designed as a prospective, open, non-controlled clinical investigation.
- Trial name
- NCT01195896
- Testing
- New NPWT system
- Where
- Germany
- Volunteers
- 9 people
- Sponsor
- Molnlycke Health Care AB
Seroma, Surgical Site Infection
Prevention of Seroma Following Inguinal Lymph Node Dissection With Prophylactic Incisional Negative Pressure Wound Therapy
Inguinal lymph node dissection (ILND) is indicated following metastatic malignant melanoma, and is associated with a high-complication rate, of which many begin with the formation of seroma and ends in complicated wound healing…
- Conditions
- Seroma, Surgical Site Infection, Lymphedema, Quality of Life
- Trial name
- NCT03433937
- Testing
- Negative pressure wound therapy, Micropore tape
- Where
- 4 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Incidence of Surgical Site Infection, Morality
Changing the Surgical Team for Wound Closure and Surgical Site Infection
Surgical site infection is a frequent complication after abdominal surgery. The wound closure is done at the end of the procedure when the attention of the entire team may be affected because of tiredness and reduced attention of…
- Conditions
- Incidence of Surgical Site Infection, Morality, Fascial Hernia
- Trial name
- NCT04503642
- Testing
- Changing the surgical team for wound closure
- Where
- Switzerland
- Volunteers
- 1,160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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