Clinical trials: Infection, COVID-19
SARS-CoV-2 Infection, Influenza A
Usability and Clinical Validation of the Flu A/B/COVID-19 + RSV Multiplex Rapid Test
This will be a prospective study for the clinical validation of the CorDx Tyfast Flu A/B/COVID-19 + RSV Multiplex Rapid Test for the qualitative detection and differentiation of SARS-CoV-2, Influenza A, Influenza B and RSV in AN…
- Conditions
- SARS-CoV-2 Infection, Influenza A, Influenza B, RSV
- Trial name
- CorDx 4in1 (NCT07875270)
- Testing
- Flu A/B/COVID-19 + RSV Multiplex Rapid Test
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- CorDx, Inc.
Long Covid19, Autonomic Dysfunction
Autonomic Nervous System Affection Due to Post Covid Syndrome
Post-Covid syndrome is defined as symptoms that develop in addition to respiratory symptoms in individuals who have had Covid-19 infection for more than 12 weeks.
- Trial name
- NCT05502094
- Testing
- Heart Rate Variability Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Long COVID, Post COVID-19 Condition
Taurine Supplementation in Adolescents With Post-COVID Condition
The COVID-19 pandemic has swept across the globe, affecting millions of individuals with varying degrees of severity. While many individuals recover from the acute phase of the infection, a significant proportion continue to…
- Conditions
- Long COVID, Post COVID-19 Condition, PASC Post Acute Sequelae of COVID 19
- Trial name
- TaurineLCPeds (NCT07682402)
- Testing
- Taurine
- Volunteers
- 30 people
- Sponsor
- University of Alberta
COVID-19
Study of Remdesivir in Participants Below 18 Years Old With COVID-19
The goals of this clinical study are to learn more about the study drug, remdesivir, and how safe it is in participants less than 18 years old with coronavirus disease 2019 (COVID-19).
- Trial name
- CARAVAN (NCT04431453)
- Testing
- Remdesivir
- Where
- 32 sites in United States, Italy and 2 more
- Volunteers
- 59 people
- Sponsor
- Gilead Sciences
Covid19, Patient Reported Outcome Measures, Quality of Life
Development of an International COVID-19 Specific Quality of Life Questionnaire, Phase III. The OSLO COVID-19 QLQ
Purpose: to develop an international validated patient-reported outcome measure for COVID-19 patients according to international guidelines.
- Trial name
- NCT04740372
- Testing
- No intervention. Method study. Psychometric testing
- Where
- Norway
- Volunteers
- 371 people
- Sponsor
- Oslo University Hospital
Covid19
Short Term Low Dose Corticosteroids for Management of Post covid19 Pulmonary Fibrosis
A randomized controlled trial to study the efficacy of low dose steroid for 14 days in the treatment of post-covid-19 lung infiltrates
- Trial name
- NCT04551781
- Testing
- 20 Mg Prednisone for 14 days, control
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- South Valley University
Loneliness
Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness
The primary aim of this study is to examine the efficacy of a one-session, hour-long HIPAA-compliant video platform-based mindfulness + compassion telehealth intervention on reducing feelings of loneliness during COVID-19…
- Trial name
- NCT04414826
- Testing
- Mindfulness Alone (MO) Intervention, Mindfulness + Compassion Intervention (MC)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
COVID-19
Evaluating the Safety and Efficacy of AD17002 Intranasal Spray in Treating Participants With Mild to Moderate COVID-19
AD17002 enhances nasal mucosal innate immunity and has met safety and efficacy endpoints in studies of nasal adjuvants or intranasal immunomodulators.
- Trial name
- NCT05541510
- Testing
- AD17002 + Formulation buffer
- Where
- 3 sites in Indonesia
- Volunteers
- 180 people
- Sponsor
- Advagene Biopharma Co. Ltd.
Covid19, ARDS
Noninvasive Ventilation in Moderate-to-severe COVID-19-associated Acute Respiratory Distress-syndrome
Non-invasive ventilation can allow to avoid intubation and improve outcomes in moderate-to-severe COVID-19-associated acute respiratory distress-syndrome (ARDS).
- Trial name
- COVID-NIV (NCT04667923)
- Testing
- Respiratory monitoring, Respiratory muscles ultrasound, Electro impedance tomography
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
COVID-19 Pneumonia, COVID-19 Respiratory Infection
Safety and Effectiveness of an Immunobiological Drug in CoViD-19
The aims of this study is to analyze the efficacy and safety of a passive immunotherapy strategy using hyperimmune equine serum known as Anti-SARS-CoV-2 elaborated by the National Institute for the Production of Biologicals…
- Conditions
- COVID-19 Pneumonia, COVID-19 Respiratory Infection, Covid19
- Trial name
- INPB001 (NCT04913779)
- Testing
- Anti-SARS-CoV-2
- Where
- Argentina
- Volunteers
- 200 people
- Sponsor
- Administracion Nacional de Laboratorios e Institutos de Salud Dr. Carlos G. Malbran
Covid19
Evaluation of the Efficacy of High Doses of Methylprednisolone in SARS-CoV2 ( COVID-19) Pneumonia Patients
This double blind, randomized study is aiming to evaluate the efficacy of three doses (1gr/day) of methylpredisolone added to standard therapy in patients, with documented COVID-19 pneumonia, requiring hospitalization but not…
- Trial name
- NCT04673162
- Where
- 20 sites in Italy
- Volunteers
- 260 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Covid19, Corona Virus Infection
SPI-1005 Treatment in Moderate COVID-19 Patients
The study is a randomized, double-blind, placebo-controlled, dose escalation, multi-center clinical trial (RCT) of SPI-1005 in adult subjects with positive PCR test for novel SARS-CoV-2 (nCoV2) and moderate symptoms of COVID-19…
- Conditions
- Covid19, Corona Virus Infection, Coronavirus, Coronavirus Infection
- Trial name
- NCT04484025
- Testing
- Ebselen
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Aging, SARS-CoV-2 Infection
Impact of the COVID-19 Pandemic on the Health Status of People Aged 75 and Over and Their Caregivers
The measures to control the transmissibility of the Covid-19 pandemic have changed the daily routines of the population, increasing sedentary lifestyles, decreasing outdoor physical activity and limiting contact with neighbors…
- Conditions
- Aging, SARS-CoV-2 Infection, Caregivers, Frailty
- Trial name
- CUIDAMOS+75 (NCT05249868)
- Testing
- Exposure SARS-CoV-2 Infection
- Where
- 2 sites in Spain
- Volunteers
- 1,035 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Covid19
DYNamic Assessment of Multi Organ Level Dysfunction in Patients Recovering From Covid-19
In this study the investigators are hoping to the find out what changes occur within the body of people recovering from Covid-19 at 5-7 months and 11-13 months following discharge from hospital, compared to healthy controls, and…
- Trial name
- DYNAMOCovid-19 (NCT05060497)
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Covid19, Exercise
Inspiratory Muscle Training in COVID-19 Patients
This study aims to investigate whether adjunctive inspiratory muscle training (IMT) can enhance the benefits of pulmonary rehabilitation (PR) in patients with COVID-19.
- Trial name
- ADDIMTCOVID (NCT04595097)
- Testing
- inspiratory muscle traiing
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- Escola Superior de Ciencias da Saude
COVID-19, Severe Acute Respiratory Syndrome
Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection (HYDRA Trial)
Double blinded randomized clinical trial designed to evaluate the security and efficacy of hydroxychloroquine as treatment for COVID-19 severe respiratory disease.
- Trial name
- HYDRA (NCT04315896)
- Testing
- Hydroxychloroquine
- Where
- Mexico
- Volunteers
- 320 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Corona Virus Infection
Persistence of Symptoms After Improvement of Acute COVID-19
Coronavirus disease pandemic has been started in late 2019. Survivors of COVID-19 are significantly more likely to develop clinical sequelae three months after discharge from the hospital than those without COVID-19 infection.
- Trial name
- COVID-19 (NCT04764773)
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Sohag University
COVID-19, Acute Respiratory Distress Syndrome
Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure
This is a research study to see how safe and effective decidual stromal cells are in treating patients with respiratory failure (breathing problem where not enough oxygen is passed from the lungs into the blood) caused by…
- Trial name
- NCT04451291
- Testing
- Decidual Stromal Cells (DSC)
- Where
- 3 sites in Canada
- Volunteers
- 19 people
- Sponsor
- University Health Network, Toronto
COVID19
Evaluation of the AudibleHealth Dx AI/ML-Based Dx SaMD Using FCV-SDS in the Diagnosis of COVID-19 Illness
The AudibleHealth Dx is a diagnostic software as a medical device (Dx SaMD) consisting of an ensemble of software subroutines that interacts with a proprietary database of Signal Data Signatures (SDS), using Artificial…
- Trial name
- NCT05175690
- Testing
- Diagnostic Software as Medical Device
- Where
- United States
- Volunteers
- 1,126 people, healthy volunteers welcome
- Sponsor
- AudibleHealth AI, Inc.
Sars Cov 2
Outpatient Treatment With CoVid-19 With Prexablu
Within the epidemic context of phase 3 in Mexico, the implementation of new treatments that have been shown to be beneficial for patients in other countries is an urgent need.
- Trial name
- NCT04619290
- Testing
- Sublingual Methylene blue, Control patients
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Hospital Reg. Lic. Adolfo Lopez Mateos
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