Clinical trials: Infection, COVID-19
Development, Infant, Development Delay
The Effect of the Covid 19 Pandemic Process on the Neuromotor Developments of 6-24 Month-old Babies
Development; It covers the areas of physical, mental, emotional and social development. Development in one area affects other areas as well. Infancy is the period in which children grow and develop the fastest.
- Trial name
- NCT05778357
- Testing
- Group1
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Covid19, Anxiety
COVID-19 (Coronavirus Disease-2019) Psychiatric Outcomes
The goal of this longitudinal and observational study is to better understand the psychiatric consequences of COVID-19 over time.
- Conditions
- Covid19, Anxiety, Mood, Cognitive Impairment
- Trial name
- NCT05119400
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Weill Medical College of Cornell University
Coronavirus
Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19)
This multi-center, open-label, 2 arm parallel-group, randomized, interventional prospective exploratory study in 40 patients aimed to evaluate safety and explore putative clinical benefits of Silmitasertib 1000 mg BID dose in…
- Trial name
- CX4945 (NCT04668209)
- Testing
- Silmitasertib
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Arizona
SARS-CoV2 Infection, SARS-CoV-2 Acute Respiratory Disease
SABRE: A Single-arm Prospective Study Measuring Safety and Tolerability of SARS-CoV-2 Neutralising Antibodies in High-risk Populations
The SABRE study is a single-arm prospective study measuring safety, tolerability and pharmacokinetics of two SARS-CoV-2 neutralising antibodies (BMS-986414 and BMS-986413) amongst high-risk special populations of vaccine…
- Conditions
- SARS-CoV2 Infection, SARS-CoV-2 Acute Respiratory Disease, Myeloma, Leukemia
- Trial name
- SABRE (NCT05393999)
- Testing
- BMS-986414, BMS-986413
- Where
- United Kingdom
- Sponsor
- Imperial College Healthcare NHS Trust
Covid19, Anxiety
COVID-19 - No Health Without Mental Health
The Corona pandemic is affecting the whole world and since March 12.th 2020 there has been strict qurantene and social isolation interventions in Norway.
- Trial name
- Co-COVID-19 (NCT04421612)
- Testing
- Co-mestring (co-coping)
- Where
- Norway
- Volunteers
- 91 people
- Sponsor
- Haukeland University Hospital
Myocarditis, Pericarditis
A Study on the Clinical Course, Outcomes and Risk Factors of Myocarditis and Pericarditis After Moderna COVID-19 Vaccine
The main goal of this study is to describe the clinical course, outcomes and risk factors for myocarditis and pericarditis associated with Moderna vaccination targeting SARS-CoV-2.
- Trial name
- NCT06113692
- Testing
- mRNA-1273
- Where
- 5 sites in Denmark, Norway and 2 more
- Volunteers
- 1,169 people
- Sponsor
- ModernaTX, Inc.
Covid19
Colchicine for the Treatment of Cardiac Injury in Hospitalized Patients With COVID-19 (COLHEART-19)
This is an open-label unblinded, randomized study to treat hospitalized covid-19 patients with colchicine plus current care (per institution treating physicians) vs.
- Trial name
- Colheart-19 (NCT04762771)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Baptist Health South Florida
Alzheimer Disease, Telerehabilitation
Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease
Our aim has been determined to investigate the effect of physical exercise alone and in combination with cognitive exercise, on cognitive, physical function and quality of life in individuals with Alzheimer's Disease during the…
- Conditions
- Alzheimer Disease, Telerehabilitation, Online Physical Exercise, Computerized Cognitive Stimulation
- Trial name
- NCT04842734
- Testing
- Physical exercise, Physical exercise and computerized cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yeditepe University
COVID-19, Vaccination Hesitancy
An Online Game to Help Canadian Adults Identify COVID-19 Vaccine Misinformation With One-Month Follow-Up
COVID-19 vaccine misinformation contributed to vaccine hesitancy and preventable illness. This study tested whether a brief online game helps Canadian adults identify COVID-19 vaccine misinformation, and whether effects last one…
- Conditions
- COVID-19, Vaccination Hesitancy, Health Misinformation, Communication
- Trial name
- NCT07758296
- Testing
- Gamified misinformation refutation quiz, Refutational text blog post (active control)
- Where
- United States
- Volunteers
- 4,071 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Covid19, Telerehabilitation
The Effectiveness of Telerehabilitation-Based Physiotherapy in COVID 19 Patients
Problems such as breathlessness, exercise intolerance and loss of peripheral muscle strength can be observed in individuals who have been diagnosed with COVID19 and have been discharged.
- Conditions
- Covid19, Telerehabilitation, Physical Therapy
- Trial name
- NCT04402983
- Testing
- Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul Medipol University Hospital
SARS-Cov-2, Covid19
Clinical Evaluation of a Point-of-Care (POC), SARS-CoV-2 (COVID-19) IgG Antibody Test in Fingerstick Whole Blood
Prospective, multi-center, observational, blinded clinical trial to compare a new point of care (POC) SARS-CoV-2 IgG antibody test to a reference SARS-CoV-2 PCR test using fingerstick whole blood.
- Trial name
- NCT04699903
- Testing
- POC SARS-Cov-2 IgG Antibody test
- Where
- 3 sites in United States
- Volunteers
- 201 people
- Sponsor
- Lumos Diagnostics
COVID-19
Duvelisib Ameliorates Manifestations of Pneumonia in Established Novel Coronavirus Infection (COVID-19)
In this study, patients with severe coronavirus disease 2019 (COVID-19) infection will be randomized to receive duvelisib or a placebo.
- Trial name
- DAMPEN-CI (NCT04487886)
- Testing
- Duvelisib
- Where
- 3 sites in United States
- Volunteers
- 47 people
- Sponsor
- Emory University
Smell Dysfunction, Olfactory Disorder
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
Persistent smell loss that can include diminished or distorted smell function is a common symptom of long COVID syndrome. There are limited treatment options for long COVID-related smell loss.
- Conditions
- Smell Dysfunction, Olfactory Disorder, Long COVID
- Trial name
- NCT05855369
- Testing
- Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Medical University of South Carolina
Mental Health Impairment
National Survey of Mental Health After COVID-19 Outbreak
The Serbian national survey - acronym CoV2Soul.RS - has been launched to document mental health (MH) status and understand needs of the population in relation to the prolonged global public health crisis.
- Trial name
- CoV2SoulRS (NCT04896983)
- Where
- 3 sites in Serbia
- Volunteers
- 1,200 people
- Sponsor
- University of Belgrade
Mental Health Wellness 1, Addiction
Finding Wellness in the Pandemic
There is an immediate need for population-level intervention research to address the impacts of the coronavirus disease 2019 (COVID-19) pandemic and its containment measures on mental health and substance use (MHSU).
- Conditions
- Mental Health Wellness 1, Addiction, Stress, Psychological, Covid19
- Trial name
- NCT04615741
- Testing
- Trauma Informed Yoga, Trauma Informed Psychotherapy
- Where
- Canada
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Respiratory Tract Infections (RTI), Mucosal Immunity
To Evaluate Mucosal and Systematic Immune Response to Acute Respiratory Tract Infections of South African Children
The goal of this observational study is to answer a few questions about respiratory tract infections in South African children: 1.
- Trial name
- Muco-Kids (NCT06902194)
- Where
- 2 sites in South Africa
- Volunteers
- 250 people
- Sponsor
- Desmond Tutu TB Centre
COVID-19, Hypoxemic Respiratory Failure
The Effect of Non-invasive Respiratory Support on Outcome and Its Risks in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2)-Related Hypoxemic Respiratory Failure
Coronavirus disease (COVID-19) can result in severe hypoxemic respiratory failure that ultimately may require invasive mechanical ventilation in the Intensive Care Unit (ICU).
- Trial name
- NORMO2 (NCT06033560)
- Testing
- High flow nasal oxygen (HFNO, more than 15 L/min)
- Where
- Netherlands
- Volunteers
- 6,000 people
- Sponsor
- Amsterdam UMC, location VUmc
COVID-19
A Phase III Study of COVID-19 Vaccine EuCorVac-19 in Healthy Adults
This is a phase III, randomized, observer-blind, active-controlled, parallel group, multi-center study to compare the immunogenicity and safety of a preventive COVID-19 vaccine EuCorVac-19 to ChAdOx1 in healthy adults aged 18…
- Trial name
- NCT05572879
- Testing
- EuCorVac-19, ChAdOx1 nCoV-19
- Where
- Philippines
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- EuBiologics Co.,Ltd
COVID-19, COVID-19 Pneumonia
Retrospective Evaluation of Lung Pathology in Subjects With COVID-19
Non-interventional, retrospective, multi-center, follow-up study evaluating the effect of C21 on lung pathology in subjects previously hospitalised with COVID-19 and enrolled in the VP-C21-006 trial.
- Trial name
- ATTRACT-2 (NCT04878913)
- Testing
- C21
- Where
- 4 sites in India
- Volunteers
- 35 people
- Sponsor
- Vicore Pharma AB
Lifestyle-related Condition, COVID-19 Pandemic
Lifestyle Changes by the COVID-19 (Coronavirus Disease 2019) Pandemic in Children With Developmental Delays
To evaluate the lifestyle changes caused by the COVID-19 pandemic in children with developmental delays in Taiwan.
- Conditions
- Lifestyle-related Condition, COVID-19 Pandemic, Children With Developmental Delays
- Trial name
- COVID-19 (NCT05770362)
- Testing
- lifestyle questionnaire
- Where
- Taiwan
- Volunteers
- 260 people
- Sponsor
- Taipei Medical University
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