Clinical trials: Infection, COVID-19
Covid19
Effect of Tenofovir/Emtricitabine in Patients Recently Infected With SARS-COV2 (Covid-19) Discharged Home
COVID-19 pandemic is currently affecting the globe. To date, there is no effective oral therapy against SARS-CoV2 infection. The investigators propose to test as a repurposing drug combination, a short course of tenofovir…
- Trial name
- AR0-CORONA (NCT04685512)
- Testing
- tenofovir disoproxil and emtricitabine
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Anxiety and Fear, Anxiety Depression
Psychological Well-being of Patients Awaiting for Cardiac Surgery During the COVID-19 Pandemic
The effect and impact of postponing cardiac surgery / creating a waiting list as a result of COVID-19 on patients, both psychologically and symptomatically on three groups of patients: 1.
- Conditions
- Anxiety and Fear, Anxiety Depression, Anxiety Postoperative, Psychological Stress
- Trial name
- NCT04406181
- Testing
- HADS, a survey
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Mental Health, COVID-19
Leveraging Community Health Workers to Combat COVID-19 and Mental Health Misinformation in Haiti, Malawi, and Rwanda
Partners In Health (PIH), in collaboration with Harvard Medical School, aims to develop and evaluate an SMS-based intervention for Community Health Workers (CHWs) to combat COVID-19 and mental health-related misinformation in…
- Conditions
- Mental Health, COVID-19, Misinformation
- Trial name
- NCT05997511
- Testing
- Card-Sorting Activity (Pre-intervention design), SMS Crafting (Pre-intervention design), SMS Messaging
- Where
- 3 sites in Haiti, Malawi and 1 more
- Volunteers
- 5,109 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
COVID-19 Pandemic
SARS-CoV-2 OTC At Home Test
The objective of this study is to evaluate the 3EO Health COVID-19 Test in individuals presenting at a medical facility. In eligible subjects, nasal samples will be collected for use with the 3EO Health COVID-19 Test, which will…
- Trial name
- NCT05553964
- Testing
- In Vitro
- Where
- 5 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- 3EO Health
Heart Failure, Covid19
Impact of COVID-19 on the Benefit of Cardiac Rehabilitation
The COVID-19 attack is polymorphic with otorhinolaryngological, pneumological, cardiac, digestive, neurological, muscular attacks with a higher mortality in subjects with comorbidity [> 70 years old, cardiovascular history in…
- Trial name
- REACARDIOCOVID (NCT04513964)
- Sponsor
- Fondation Hôpital Saint-Joseph
COVID-19
COVID-19 Surveillance in Rural Mozambique for Prompt and Effective Response
Extraordinary times require extraordinary measures. The current COVID-19 pandemic is the paradigmatic example of how infectious diseases may menace the world's health and economy, and particularly contribute to enhancing current…
- Trial name
- MozCOVID (NCT05228639)
- Where
- Mozambique
- Volunteers
- 6,494 people, healthy volunteers welcome
- Sponsor
- Centro de Investigacao em Saude de Manhica
SARS-Cov2
COVID-19 Epidemiological Surveillance on Healthcare Workers and Patients in a Rehabilitation Medicine Facility
The recent SARS-CoV2 pandemic has highlighted that the transmission of the virus within health care facilities plays a fundamental role in its propagation and, therefore, in the increase in COVID-19 cases registered among…
- Trial name
- COVID-19 (NCT04913701)
- Testing
- Observation group 1
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Public Health, Demography
COVID-19 Health Messaging Efficacy and Its Impact on Public Perception, Anxiety, and Behavior
Effective communication is a critical component of managing pandemic outbreaks like COVID-19. This study explores COVID-19 related public knowledge, perceptions, belief in public health recommendations, intent to comply with…
- Conditions
- Public Health, Demography, Pandemics, Corona Virus Infection
- Trial name
- NCT04377581
- Where
- United States
- Volunteers
- 18,251 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
SARS-CoV 2
Severe Acute Respiratory Syndrome-Coronavirus-2 and Loss of Autonomy in the Elderly
In most diseases, older people have less typical symptomatology than that described for younger people. The investigators therefore hypothesize that within the framework of coronavirus disease 19, the clinical pictures in the…
- Trial name
- CovAged (NCT04414319)
- Where
- 5 sites in France, Guadeloupe and 1 more
- Volunteers
- 170 people
- Sponsor
- University Hospital Center of Martinique
Covid19
Hematology and Clinical Picture in Pediatric COVID-19 Infection
This study is to discuss the different clinical presentations, hematological and laboratory abnormalities in pediatric COVID-19 infection.
- Trial name
- NCT04487119
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Benha University
Anxiety, Pandemic, COVID-19
Preoperative Anxiety During COVID-19
The modified Preoperative Anxiety Scale (mPAS) questionnaire as given in the article by Viola et al, will be used after permission from the authors, to investigate the preoperative anxiety of patients undergoing surgery during…
- Trial name
- NCT05114967
- Testing
- mPAS questionnaire
- Where
- Greece
- Volunteers
- 116 people
- Sponsor
- University of Thessaly
SARS-CoV-2 Infection
Tocilizumab in the Treatment of Coronavirus Induced Disease (COVID-19)
The mortality rate of the disease caused by the corona virus induced disease (COVID-19) has been estimated to be 3.7% (WHO), which is more than 10-fold higher than the mortality of influenza.
- Trial name
- CORON-ACT (NCT04335071)
- Testing
- Tocilizumab (TCZ)
- Where
- 4 sites in Switzerland
- Volunteers
- 5 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
COVID
Telerehabilitation After Coronavirus
The aim of the study is to investigate the effects of telerehabilitation program on COVID-19 symptoms, quality of life, level of depression, perception of dyspnea, sleep, fatigue, kinesiophobia and patient satisfaction in…
- Trial name
- NCT04473898
- Testing
- Aerobic Exercise Training, Patient Education, Respiratory Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- KTO Karatay University
Solid Organ Transplant Recipients
TIXAGEVIMAB/CILGAVIMAB Protection of Covid-19 in Transplanted Patients
Covid-19 has a very bad prognosis in solid organ transplant recipients with a 60 days-mortality exceeding 20%. For this reason, transplant patients were prioritized to receive Covid-19 vaccination since December 2020 in France.
- Trial name
- TIXCI-TRANS (NCT05234398)
- Testing
- Blood and saliva samplings
- Where
- 2 sites in France
- Sponsor
- Hospices Civils de Lyon
COVID-19
Relationship Between CT- Value With Prognosis in COVID-19 Patients
evaluate the relationship between cycle threshold number with final prognosis in COVID-19 patients
- Trial name
- NCT04902157
- Testing
- Cycle threshold
- Where
- 2 sites in Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
COVID-19
Safety and Immunogenicity Study of AdCLD-CoV19: A COVID-19 Preventive Vaccine in Healthy Volunteers
This is a Phase 1/2a clinical trial to assess the safety and immunogenicity of AdCLD-CoV19 in healthy adults.
- Trial name
- NCT04666012
- Testing
- AdCLD-CoV19
- Where
- 5 sites in South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cellid Co., Ltd.
Covid19
Protecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019
The purpose of this study is to determine the effect of sacubitril/valsartan versus placebo on markers of cardiac injury, structure, and function among patients who recovered from acute COVID-19 infection.
- Trial name
- PARACOR-19 (NCT04883528)
- Testing
- Sacubitril / Valsartan Oral Tablet [Entresto]
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Duke University
COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
This is a phase I trial followed by a phase II randomized trial. The purpose of phase I study is the feasibility of treating patients with acute respiratory distress syndrome (ARDS) related to COVID-19 infection (COVID-19) with…
- Conditions
- COVID-19 Infection, COVID-19-Associated Acute Respiratory Distress Syndrome, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04565665
- Testing
- Best Practice, Mesenchymal Stem Cell
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- M.D. Anderson Cancer Center
Vaccine Hesitancy
Investigation on the Hesitancy of COVID-19 Vaccination Among Liver Transplant Recipients in China
On WeChat platform, through a point-to-point connection, and carry on the questionnaire survey to collect information of liver transplant recipients followed-up by the department of Liver Surgery, Renji Hospital Shanghai Jiao…
- Trial name
- NCT05532592
- Testing
- Perceptions and attitudes towards COVID-19 and COVID-19 vaccine
- Where
- China
- Volunteers
- 449 people
- Sponsor
- RenJi Hospital
Covid19
Long-term Effects of COVID-19 in Adolescents
The overarching objective for this prospective cohort study of COVID-19 in adolescents is to study the long-term effects, with particular emphasis on post-infectious chronic fatigue.
- Trial name
- LoTECA (NCT04686734)
- Testing
- No active intervention (observational only)
- Where
- Norway
- Volunteers
- 516 people
- Sponsor
- University Hospital, Akershus
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