Clinical trials: Infection, COVID-19
COVID-19
Hydroxychloroquine Use in Hospitalized Patients With COVID-19: Impact on Progression to Severe or Critical Disease
The primary objective is to assess the impact of hydroxychloroquine in hospitalized patients with COVID-19 and risk factors for severe/critical disease.
- Trial name
- NCT04429867
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- WellStar Health System
COVID-19, COVID19
A Study of Hydroxycholoroquine Compared to Placebo as Treatment for People With COVID-19
This study is being done to see if hydroxychloroquine is an effective treatment for COVID-19.
- Conditions
- COVID-19, COVID19, Sars-CoV2, SARS-Cov-2
- Trial name
- NCT04379492
- Testing
- Hydroxychloroquine
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Anxiety Depression, Alcohol Abuse
CBD Oil for Reducing Emotional Impact of COVID-19
Our purpose is to conduct a 4-arm placebo-controlled clinical trial to investigate the relative clinical efficacy of 300 mg. of pure hemp-derived CBD isolate, 300 mg. of full spectrum CBD oil, 300 mg.
- Conditions
- Anxiety Depression, Alcohol Abuse, Substance Abuse, Anger
- Trial name
- CBDOIL (NCT04603781)
- Testing
- CBD Isolate, Full Spectrum CBD Oil, Broad-Spectrum CBD Oil
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
HIV-1-infection, SARS-CoV Infection
SARS-CoV-2 (COVID-19) Antibody PrevalencE in an Adult London HIV Cohort
Prospective, observational SARS-CoV2 serological surveillance single London HIV outpatient center study using NHS participants
- Conditions
- HIV-1-infection, SARS-CoV Infection, Covid19
- Trial name
- SCAPE-HIV (NCT05067400)
- Where
- United Kingdom
- Volunteers
- 615 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
COVID-19
Classification of COVID-19 Infection in Posteroanterior Chest X-rays
The objective of this study is to assess three configurations of two convolutional deep neural network architectures for the classification of COVID-19 PCX images.
- Trial name
- NCT04358536
- Testing
- CovX
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Dascena
SARS-CoV 2, COVID-19
Assessment of the Psycho-social Impact of COVID-19 Outbreak
It has been shown in previous important outbreaks of infectious diseases that they have a huge impact on individuals and communities.
- Conditions
- SARS-CoV 2, COVID-19, Quality of Life, Mental Health Wellness 1
- Trial name
- COM-COVID (NCT04378452)
- Testing
- COM-COVID anonimous survey
- Where
- 4 sites in Spain
- Volunteers
- 56,656 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Healthy
A Trial to Learn if a COVID-19 Therapeutic is Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants
The primary objective of the study is to evaluate the safety and tolerability of REGN14284 in healthy participants, as measured by all treatment-emergent adverse events (TEAEs) and treatment-emergent serious adverse events…
- Trial name
- NCT05505448
- Testing
- REGN14284
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Disseminated Intravascular Coagulation, Critical Illness
Thrombomodulin-modified Thrombin Generation Assay (TGA-TM) in Patients With Critical Infections
Inflammation and abnormalities in laboratory coagulation tests are inseparably tied. For example, coagulation abnormalities are nearly universal in septic patients.
- Conditions
- Disseminated Intravascular Coagulation, Critical Illness, Sars-CoV2, Viral Infection
- Trial name
- NCT04356144
- Testing
- Thrombin Generation Assay (TGA), Thrombomodulin Modified Thrombin Generation Assay (TGA-TM)
- Where
- Austria
- Volunteers
- 58 people
- Sponsor
- Medical University of Vienna
Covid19
Clinical Trial Evaluating the Efficacy and Safety of Favipiravir in Moderate to Severe COVID-19 Patients
This is a prospective, interventional, multi-centre, phase III, randomized, double blind, placebo-controlled, parallel design trial to evaluate the efficacy, safety and tolerability of favipiravir as adjunct ('add on') to…
- Trial name
- NCT04529499
- Testing
- AVIGAN
- Where
- 2 sites in Kuwait
- Volunteers
- 353 people
- Sponsor
- Dr. Reddy's Laboratories Limited
COVID-19, SAR-CoV-2
Long-term Effects of COVID-19
The purpose of this study is to measure, monitor, and analyze long term effects of SARS-CoV-2. The main purpose is to assess the post-hospitalization outcomes of patients who were diagnosed with SAR-CoV-2 by comparing to patients…
- Trial name
- NCT05220514
- Testing
- (R)-1-(2-chlorophenyl)- N-[11C] ([11C] PK11195), 2-(4-[11C]methylamino phenyl)-6-hydroxybenzothiazole (11C]6-OH-BTA-1 or [11C]PIB)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Mayo Clinic
COVID-19
Assessment of Incidence of SARS-CoV-2 Infection and COVID-19 in Brazil (AVISA)
This is an observational study, meaning that no interventions is tested, to determine incidence of SARS-CoV-2 infection and COVID-19 in different clinical sites in Brazil in several age groups.
- Trial name
- AVISA (NCT04355338)
- Where
- 11 sites in Brazil
- Volunteers
- 3,520 people, healthy volunteers welcome
- Sponsor
- Butantan Institute
Coronavirus Infection
Covid-19, Hospitalized, PatIents, Nasafytol
The objective of this study is to evaluate the effect and safety of NASAFYTOL® on COVID-19 positive hospitalized patients as a supportive supplementation to standard-of-care in improving clinical parameters safely during hospital…
- Trial name
- NCT04844658
- Testing
- NASAFYTOL®, FULTIUM® -D3 800, Strandard of care treatment
- Where
- Belgium
- Volunteers
- 51 people
- Sponsor
- Tilman S.A.
Type2 Diabetes, Covid19
Advancing DSME/S and COVID-19 Prevention and Protection Through "emPOWERed to Change" Program
African Americans (AA)/People of Color (POC) are disproportionately impacted by COVID-19 to an extent not observed in other racial/ethnic subgroups.
- Trial name
- NCT04993326
- Testing
- emPOWERed To Change Program
- Sponsor
- Charles Drew University of Medicine and Science
Covid19
Prevalence of Thrombosis in COVID-Patients
Examination of the prevalence of thrombosis in COVID-patients, especially in an out-patient setting. Assessment by duplex sonography. If thrombosis is detected, we will correlate it with immunity status.
- Trial name
- NCT04615026
- Testing
- duplex sonography
- Where
- Germany
- Volunteers
- 525 people
- Sponsor
- University Hospital Augsburg
Covid19, SARS-CoV Infection
COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes
The purpose of this study is to test whether Fisetin, a senolytic drug, can assist in preventing an increase in the disease's progression and alleviate complications of coronavirus due to an excessive inflammatory reaction.
- Trial name
- COVID-FIS (NCT04537299)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
SARS-CoV-2 Infection
Asymptomatic COVID-19 Trial
The coronavirus disease-2019 (COVID-19) is spreading throughout the United States. While there are no known therapies to treat those who have become sick, there have been some reports that a medication currently used to treat…
- Trial name
- ACT (NCT04374552)
- Testing
- Hydroxychloroquine sulfate &Azithromycin
- Where
- United States
- Sponsor
- Rutgers, The State University of New Jersey
Post-acute Covid-19 Syndrome
Homeopathic Treatment of Post-acute COVID-19 Syndrome
To determine whether an individually prescribed homeopathic medicine has an effect greater than a placebo and is a viable treatment option to improve fatigue and quality of life for patients suffering from the symptoms of…
- Trial name
- NCT05104749
- Testing
- Homeopathic Medication
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Southwest College of Naturopathic Medicine
Renal Insufficiency
Association Between COVID-19 and UTIs Caused by ESBL Organism in Infants
Urinary tract infections (UTIs) in infants and young children are one of the most common bacterial infections, usually febrile illness without source, frequently due to Enterobacteriaceae, mainly Escherichia coli.
- Trial name
- ABCUCEOI (NCT05630326)
- Testing
- comparing, prevalence, assessment, association
- Where
- Qatar
- Volunteers
- 5,600 people
- Sponsor
- Hamad Medical Corporation
Covid19, Viral Pneumonia Human Coronavirus
Methylprednisolone vs. Dexamethasone in COVID-19 Pneumonia (MEDEAS RCT)
Low-dose glucocorticoid treatment is the only intervention shown to significantly reduce mortality in cases of COVID-19 pneumonia requiring oxygen supplementation or ventilatory support.
- Conditions
- Covid19, Viral Pneumonia Human Coronavirus, Severe Acute Respiratory Syndrome
- Trial name
- MEDEAS (NCT04636671)
- Testing
- Methylprednisolone, Dexamethasone
- Where
- Italy
- Volunteers
- 690 people
- Sponsor
- University of Trieste
COVID-19
Ivermectin for Severe COVID-19 Management
In this multicenter study; it was aimed to investigate the effectiveness and safety of ivermectin use in the treatment of patients with severe COVID-19 pneumonia that have no mutations which alter ivermectin metabolism and cause…
- Trial name
- NCT04646109
- Testing
- Ivermectin
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
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