Clinical trials: Infection, COVID-19
COVID-19
Therapeutic Plasmapheresis in Critically Ill Adult Patients With COVID-19 Confirmed Diagnosis
Introduction: The SARS-CoV-2 outbreak has left more than two million infected worldwide in the first four months of COVID-19 epidemic.
- Trial name
- PLASMA (NCT04480632)
- Testing
- Convalescent plasma
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación Cardiovascular de Colombia
Coronavirus Disease 2019 (COVID-19)
Increased Risk of Severe Coronavirus Disease 2019 in Patients With Vitamin D Deficiency
In this prospective observational study we aim to study the association of vitamin D deficiency with adverse clinical outcomes in patients infected with Coronavirus disease 2019
- Trial name
- COVIT-D (NCT04403932)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital San Carlos, Madrid
COVID-19
Evaluating Emetine for Viral Outbreaks (EVOLVE)
The goal of this clinical trial (phase 2/phase 3) is to evaluate the efficacy and safety of emetine administered orally for symptomatic Covid-19 patients in patients ages 30 years and above.
- Trial name
- EVOLVE (NCT05889793)
- Testing
- Emetine Hydrochloride
- Where
- 2 sites in United States, Nepal
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
COVID-19
Cannabidiol Treatment for Severe and Critical Coronavirus (COVID-19) Pulmonary Infection
Current management of COVID-19 (coronavirus) is mainly supportive, and respiratory failure from acute respiratory distress syndrome (ARDS) is the leading cause of mortality.
- Trial name
- NCT04731116
- Testing
- Cannabidiol
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
COVID 19 Disease
Tafenoquine in Patients With Mild to Moderate COVID-19
A clinical study to assess the efficacy and safety of oral tafenoquine compared to placebo in patients with mild to moderate COVID 19 disease.
- Trial name
- NCT04533347
- Testing
- Tafenoquine Oral Tablet
- Where
- 10 sites in United States
- Volunteers
- 86 people
- Sponsor
- 60 Degrees Pharmaceuticals LLC
COVID-19
Thorax Computed Tomography Severity Score and Outcome in COVID-19 Patients
The most common thorax Computed tomography (CT) findings are multifocal ground-glass opacities and peripheral consolidation in patients with COVID-19.
- Trial name
- NCT04424849
- Testing
- CT-Scan
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tepecik Training and Research Hospital
Covid-19, Coronavirus Infection
Physical Activity Level, Stress Level, Sleep Quality in Pregnant Women During Covid-19 Quarantine
We hypothesized: During the COVID-19 pandemic, the sleep quality of pregnant women decreases. During the COVID-19 epidemic, the stress level of pregnant women increases.
- Conditions
- Covid-19, Coronavirus Infection, Pregnancy Related
- Trial name
- NCT04336787
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Kültür University
Long COVID, PASC Post Acute Sequelae of COVID 19
Brain Stimulation in Long COVID
Cognitive problems and severe fatigue are two frequently occurring symptoms in long COVID, also known as Post-Covid Condition or Post-Acute Sequelae of COVID-19 (PASC), and their causes are currently unknown.
- Conditions
- Long COVID, PASC Post Acute Sequelae of COVID 19, Post COVID-19 Condition (PCC)
- Trial name
- MALIBU (NCT07278206)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Amsterdam UMC, location VUmc
COVID-19 Pandemic, Eating Habit
The Effect of the COVID-19 Epidemic Process on the Nutritional Habits and Body Weights of Adults
During the COVID-19 epidemic, the time spent by adults on the stomach has increased. Therefore, the likelihood of adverse changes in lifestyles has increased.
- Conditions
- COVID-19 Pandemic, Eating Habit, Weight Gain
- Trial name
- NCT05115084
- Testing
- no intervention
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Covid-19
Recovery After Critical Covid-19 Infection
The study focuses on the recovery of respiratory, cardiovascular and neurological/neuropsychological recovery after intensive care treatment for covid-19.
- Trial name
- RECOVID (NCT04864938)
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
COVID-19
Contagiousness and Immunogenicity Status of COVID-19 in Asymptomatic Population (COVID-19 CONDITION)
In late December 2019, a new coronavirus strain emerged in China causing coronavirus disease 2019 (COVID-19). Since then, COVID-19 has become a global pandemic outbreak being declared a "public health emergency of international…
- Trial name
- CONDITION (NCT04389658)
- Where
- Spain
- Volunteers
- 1,526 people, healthy volunteers welcome
- Sponsor
- Igenomix
Covid19, Atherosclerosis
A Pragmatic Randomized Trial of Icosapent Ethyl for High-Cardiovascular Risk Adults
MITIGATE is a prospective, open-label, parallel-group, randomized, pragmatic clinical trial. The MITIGATE Study has been designed to evaluate the real-world clinical effectiveness of pre-treatment with icosapent ethyl (IPE), also…
- Conditions
- Covid19, Atherosclerosis, Cardiovascular Diseases, Upper Respiratory Tract Infections
- Trial name
- MITIGATE (NCT04505098)
- Testing
- Icosapent ethyl
- Where
- United States
- Volunteers
- 39,600 people
- Sponsor
- Kaiser Permanente
Healthy Volunteers
Study to Assess Adverse Events and How Oral ABBV-990 Moves Through the Body of Adult Healthy Participants
This study will assess how safe ABBV-990 is and how ABBV-990 moves through the body of adult healthy participants. Adverse Events will be assessed.
- Trial name
- NCT05475821
- Testing
- ABBV-990
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AbbVie
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
COVID-19 Pandemic
With Continuity of Covid-19 Pandemic, Have Our Anethetic Choices for Caesrean Section Changed ?
This retrospective analytic study will be petformed to investigate if there was a change in the choice of anaethetic technique for caesarean sections with continuation of the COVID-19 pandemic .
- Trial name
- NCT05513287
- Testing
- On the period of covid 19
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shereen salah
Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV2
Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19
The COVID-19 pandemic has had a dramatic effect in public health worldwide. In Brazil, there have been more than 2 million confirmed cases and over 75,000 deaths since February 26, 2020.
- Trial name
- RUXO-COVID (NCT04477993)
- Testing
- Janus Kinase Inhibitor (ruxolitinib)
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- Vanderson Geraldo Rocha
COVID-19, Pulmonary Fibrosis
Comparison of Pulmonary Telerehabilitation and Physical Activity Recommendations in Patients With Post Covid Fibrosis
Rehabilitation plays a very important role in the management of patients with COVID-19, focusing on respiratory and motor functions, and therefore the importance of establishing treatment strategies to ensure optimal recovery of…
- Trial name
- NCT05299333
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
COVID-19
Pulmonary Vascular Dysfunction as a Cause of Persistent Exertional Dyspnea After Coronavirus Disease (COVID-19)
To identify pulmonary vascular disease in post/long-COVID-19 patients as a cause of dyspnea/exercise limitation and to differentiate it from other causes of dyspnea
- Trial name
- PulmVasC (NCT05374577)
- Testing
- pulmonary vascular dysfunction, pulmonary vascular function
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Giessen
SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome)
High Flow Nasal Cannula HFNC In Covid-19 Patients
Many non-invasive ventilatory choices are available for COVID-19 patient who are having mild to moderate respiratory distress and their use will decrease the chance of ICU admission, intubation and mechanical ventilation in…
- Trial name
- HFNC19LGH (NCT04560257)
- Testing
- High flow nasal cannula HFNC
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Lahore General Hospital
Covid19
Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Treatment of COVID-19 Acute Respiratory Distress
This is a Phase 2 study to assess COVI-MSC in the setting of current standard of care in hospitalized subjects with RT-PCR confirmed SARS-CoV-2 (COVID-19) infection and acute respiratory distress / acute respiratory distress…
- Trial name
- NCT04905836
- Testing
- COVI-MSC
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Sorrento Therapeutics, Inc.
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