Clinical trials: Infection, Hospital
Gingivitis, Periodontitis
Oral Health Care in Stroke Patients in Tertiary Care Hospital
To investigate oral care provision in stroke care settings in Pakistan. Stroke can have adverse effects on oral care and health. Little is known about current oral care practices in stroke care settings.
- Conditions
- Gingivitis, Periodontitis, Dental Hygiene
- Trial name
- NCT05114681
- Testing
- Assessment of Oral care as per patient personal choice
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
COVID-19, Hypertension
Covid-19 Patients With Hypertension and/or Kidney Diseases
1. correlation between COVID-19 and Hypertension and/or kidney diseases. 2. Assess Assess the effect of COVID-19 on patients with Hypertension and/or kidney diseases. 3.
- Conditions
- COVID-19, Hypertension, Kidney Diseases
- Trial name
- NCT05465772
- Volunteers
- 180 people
- Sponsor
- Assiut University
Pneumonia, Bacterial Pneumonia
An Effectiveness, Safety, and Microbiology Study of Doripenem in Patients With Nosocomial (Hospital-acquired) Pneumonia
The purpose of this study is to evaluate the effectiveness and safety of doripenem monohydrate in the treatment of patients with nosocomial (hospital-acquired) pneumonia.
- Conditions
- Pneumonia, Bacterial Pneumonia, Ventilator-Associated Pneumonia, Infections, Nosocomial
- Trial name
- NCT00502801
- Testing
- doripenem
- Where
- 40 sites in United States, Argentina and 7 more
- Volunteers
- 185 people
- Sponsor
- PriCara, Unit of Ortho-McNeil, Inc.
Covid19, Cytokine Release Syndrome
Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan
Beyond supportive care, there are currently no proven treatment options for coronavirus disease (COVID-19) and related pneumonia, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).Investigators have seen…
- Conditions
- Covid19, Cytokine Release Syndrome, Critical Illness, ARDS
- Trial name
- NCT04492501
- Testing
- Therapeutic Plasma exchange, Convalescent Plasma, Tocilizumab
- Where
- Pakistan
- Volunteers
- 600 people
- Sponsor
- UNICEF
Severe Infection
Chinese PICU Collaborative Network on Pathogens and Drug Resistance of Severe Infections
To investigate PICUs in major cities in China by establishing a high-quality standardized clinical database of PICU inpatients Incidence, fatality rate, pathogen distribution, anti-infective treatment of…
- Trial name
- NCT04923828
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Children's Hospital of Fudan University
Bladder Cancer, Infections
Infectious Complications After Cystectomy: A Prospective Observational Study
Patients undergoing cystectomy for either oncological or non-oncological indications are prospectively enrolled following informed consent.
- Conditions
- Bladder Cancer, Infections, Infection, Bacterial, Infection, Hospital
- Trial name
- NCT05153694
- Testing
- Cystectomy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Infections, Cardiac Arrest
Steroids and Post-resuscitation Infectious (Septic) Complications
Postresuscitation disease is characterized by post-insult systemic inflammation, adrenal insufficiency, and circulatory failure.
- Trial name
- NCT02408939
- Testing
- Stress-dose hydrocortisone
- Where
- 5 sites in France, Greece
- Volunteers
- 191 people
- Sponsor
- University of Athens
COVID-19, SARS-CoV-2
Effect of Hydroxychloroquine in COVID-19 Positive Pregnant Women
COVID-19 was declared a pandemic on March 11th. Efforts to save lives are essential as we will face increasing morbidity with rising demands on health care resources.
- Conditions
- COVID-19, SARS-CoV-2, Pregnant Women, Hydroxychloroquine
- Trial name
- HyPreC (NCT04354441)
- Testing
- hydroxychloroquine sulfate 200 MG
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
COVID-19
Evaluation of the Outcome of COVID-19 Patients Discharged Home on Oxygen Therapy
The René Dubos Hospital in Pontoise has set up a home discharge system for oxygen-requiring patients in collaboration with PRADO, a health insurance organization, or private providers.
- Trial name
- COVAMBU (NCT05684575)
- Testing
- Phone satisfaction questionnaire
- Where
- 2 sites in France
- Volunteers
- 151 people
- Sponsor
- Hôpital NOVO
Bloodstream Infection (BSI)
Prolonged Cardiopulmonary Bypass Time as Predictive Factor for in Hospital Infection
This study is to analyse the demographics and microbiological factors concerning patients undergoing cardio surgical intervention using CPB complicated with bloodstream infection (BSI) postoperatively.
- Trial name
- NCT04548167
- Where
- Switzerland
- Volunteers
- 7,064 people
- Sponsor
- University Hospital, Basel, Switzerland
Upper Respiratory Tract Infection, Acute Tracheobronchitis
A Registry Study of 100 Thousand Cases of Pediatric Patients on Reduning Injection（a Chinese Medicine Injection）Used in Hospitals in China
This study was advocated by Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences in February 2018.
- Trial name
- NCT03461692
- Testing
- patients under 14 years of age using Reduning injeciton
- Volunteers
- 100,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
COVID-19
Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital Setting
The objectives of this study are to evaluate the safety, tolerability, antiviral activity and efficacy of AT-527 in adult subjects ≥18 years of age with moderate COVID-19 and risk factors for poor outcomes (such as obesity…
- Trial name
- NCT04396106
- Testing
- AT-527
- Where
- 37 sites in United States, Argentina and 8 more
- Volunteers
- 83 people
- Sponsor
- Atea Pharmaceuticals, Inc.
Bacterial Pneumonia
Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)
This study aims to compare treatment with a fixed-dose combination (FDC) of imipenem/relebactam/cilastatin (IMI/REL) with a FDC of piperacillin/tazobactam (PIP/TAZ) in participants with hospital-acquired or ventilator-associated…
- Trial name
- RESTORE-IMI 2 (NCT02493764)
- Testing
- Imipenem, Relebactam, Cilastatin
- Volunteers
- 537 people
- Sponsor
- Merck Sharp & Dohme LLC
Sepsis
Sepse: Critical Analysis of New Sepse Definitions and Retrospective Evaluation of Sepse Protocol at a Tertiary Hospital in Brazil
Research in the databases Lilacs, BIREME, SciELO by the terms: systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis and septic shock and their equivalents in the English language.
- Trial name
- HUVR (NCT03217981)
- Testing
- Sepsis protocol
- Where
- Brazil
- Volunteers
- 506 people
- Sponsor
- Unimed Volta Redonda
Pelvic Inflammatory Disease
Rate of Pelvic Inflammatory Disease at St. Michael's Hospital
A retrospective review of women who came through the ER at SMH with a pelvic inflammatory disease (PID) or tubo-ovarian abscess (TOA) between 1995-2005.
- Trial name
- NCT00783419
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Unity Health Toronto
Pneumonia
Anemia and Pneumonia
Assess prevalence of anemia among pneumonic children aged two months up to two years.
- Trial name
- NCT05586945
- Volunteers
- 156 people
- Sponsor
- Assiut University
Infection
Active Surveillance Cultures for Multidrug Resistant Gram-Negative Organisms at an Acute Care Hospital
Active Surveillance Culture programs (ASC) have been initiated in health-care systems in recent years as a mechanism for tracking multi-drug resistant organisms (MDRO), with a goal to reduce the transfer of those organisms to…
- Trial name
- NCT04715464
- Testing
- review of surveillance cultures within the past year
- Volunteers
- 2,878 people
- Sponsor
- Methodist Health System
Chronic Hepatitis b, Women
Efficacy and Adverse Effects of Nucleoside Analogues (TDF/LDT) in Preventing Mother-to-child Transmission of HBV
Mother-to-Child-Transmission (MTCT) of HBV is the most important route in high endemic countries. Although active-passive immune prophylaxis is generally administrated to infants delivered by HBsAg positive women, there are a lot…
- Trial name
- NCT03181607
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Xingfei Pan
Respiratory Tract Infections (RTI)
Retrospective Observational Multicenter Study on the Burden of Hospitalized Patients With Respiratory Tract Infection
This multicenter retrospective real-world data study will evaluate the burden of respiratory tract infection (RTI)-related hospitalizations in up to 10 Dutch hospitals between 2018 and 2026.
- Trial name
- NCT07691216
- Testing
- Respiratory tract infection hospitalisation
- Volunteers
- 70,000 people
- Sponsor
- LOGEX
Human Immunodeficiency Virus
Effect of Aerobic Training and Ginkgo Biloba on Lipids Levels in HIV-positive Patients Undergoing Antiretroviral Treatment
The administration of antiretroviral drugs (ART) has significantly prolonged the life expectancy of people living with human immunodeficiency virus (HIV) and delayed the progression towards Acquired Immune Deficiency Syndrome…
- Trial name
- NCT06403787
- Testing
- Aerobic exercise + Ginkgo Biloba Extract, Aerobic exercise + Atorvastatin
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- University of Guadalajara