Clinical trials: Infection, Surgical Site
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Surgical Site Infection, Sternal Wound Infection
Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation.
- Trial name
- SWAG (NCT04592328)
- Testing
- Bacterial cultures taken during surgery.
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Ostomy - Ileostomy or Colostomy, Stoma Complications
Suture Choice for Ostomy Creation
The goal of this clinical trial is to learn whether chromic gut or polyglactin 910 suture results in fewer stoma complications when used to mature an enterostomy in patients undergoing planned ostomy creation.
- Conditions
- Ostomy - Ileostomy or Colostomy, Stoma Complications, Stoma Site Dermatitis, Stoma Site Infection
- Trial name
- NCT07900711
- Testing
- Chromic Gut Suture, Polyglactin 910 Suture
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Southern California
Surgical Site Infection
Antibiotics for Prevention of SSI in Obese Women Undergoing CS
Effect of cephalexin plus metronidazole on SSI better than cephalexin alone in obese women undergoing CS
- Trial name
- NCT03736187
- Testing
- Cephalexin
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hepatitis C, Chronic
Low-dose Peg-interferon Plus Ribavirin (IFN/RBV) for Prevention of Hepatocellular Carcinoma (HCC) Recurrence in Patients Who Had Surgery to Remove Primary HCC
The purpose of this study is to determine whether low-dose peg-interferon plus ribavirin therapy is effective in the prevention of hepatocellular carcinoma (HCC) in patients who had the curative resection of primary HCC.
- Trial name
- NCT00375661
- Testing
- interferon-alfa-2b and ribavirin
- Where
- 2 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Kyoto University
Surgical Site Infections
Effect of Mupirocin Dressings Versus Island Dressings on Surgical Site Infections in Elective Colorectal Surgery
Infections at the site of surgical incisions (SSIs) are the most common infection among surgical patients. Although all patients undergoing surgical procedures are at risk for developing SSIs, colorectal surgery has had…
- Trial name
- NCT02619773
- Testing
- mupirocin ointment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Urethral Stricture
A Comparative Study of the Antibacterial Effects of Two Preoperative Hair Removal Methods in Male Patients With Urethral Stricture
Male urethral stricture is one of the common diseases in urology, with risk factors including a history of hypospadias surgery, indwelling urinary catheterization or instrumental manipulation, trauma, transurethral surgery, and…
- Trial name
- NCT07508566
- Testing
- Wiping with wet wipes containing 2% chlorhexidine gluconate (CHG).
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Prevention of Postpartum Sepsis
Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis
Randomised trial comparing the efficacy and feasibility of using a sterile closing pack to reduce postpartum sepsis
- Trial name
- NCT05632705
- Testing
- Closing pack
- Where
- South Africa
- Volunteers
- 1,000 people
- Sponsor
- University of Pretoria
Stomach Cancer, Corona Virus Infection
Does Coronavirus Disease 2019 (COVID-19) Pandemic Cause a Delay in the Diagnosis of Gastric Cancer Patients?
The aim of this study is to analyze whether COVID-19 causes a delay in the diagnosis of gastric cancer patients particularly in the TNM staging of the tumor, or not and to compare the number of newly diagnosed patients with…
- Trial name
- NCT04797624
- Testing
- Gastric cancer surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Adana City Training and Research Hospital
Surgical Site Infection, Colon Surgery
D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SoC), compared to a SoC treated…
- Conditions
- Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
- Trial name
- NCT04233424
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 62 sites in United States, Bulgaria and 8 more
- Volunteers
- 977 people
- Sponsor
- PolyPid Ltd.
Surgical Wound Infection, Postoperative Wound Infection
Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Colorectal Surgery
The main objective is to study the efficacy of topical antibiotic therapy with Amoxicillin / Clavulanic acid in the prevention of surgical wound infection in patients undergoing to colorectal surgery
- Conditions
- Surgical Wound Infection, Postoperative Wound Infection, Postoperative Wound Infection Superficial Incisional, Preventive Therapy
- Trial name
- PROTOP (NCT03574090)
- Testing
- Amoxicillin Clavulanate, Physiological Saline
- Where
- Spain
- Volunteers
- 268 people
- Sponsor
- Universitat Internacional de Catalunya
Postoperative Wound Infection
Wick vs. No Wick: Does Method of Closure Affect Rate of Wound Infection?
Countless children undergo surgery annually for management of what clinicians consider to be a "dirty wound". One frequently encountered example is the ostomy reversal.
- Trial name
- NCT01691352
- Testing
- Wick dressing, No Wick
- Where
- United States
- Sponsor
- Children's Healthcare of Atlanta
Degenerative Disc Disease (DDD), Spinal Stenosis
PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials
This is a prospective, multi-center, observational Post-Market Clinical Follow-Up (PMCF) study designed to collect additional safety and clinical performance data on CE-marked Titania® spinal instrumentation and fusion systems…
- Conditions
- Degenerative Disc Disease (DDD), Spinal Stenosis, Spondylolisthesis, Spinal Deformities
- Trial name
- INFO SPINE (NCT07615491)
- Testing
- Titania® Cervical Interbody Fusion Cage (Titanium), Titania® Cervical Interbody Fusion Cage (PEEK), Titania® Posterior Cervical Stabilization System
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 561 people
- Sponsor
- Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co.
Surgical Site Infection, Surgical Wound Infection
Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections
A Randomized controlled trail to To assess the efficacy of povidone-iodine wash before wound closure in preventing surgical site infections.
- Trial name
- NCT05077592
- Testing
- 10% Povidone Iodine
- Where
- Egypt
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Wound Infection, Surgical Site Infection
Assessing Parenteral Antibiotics Versus Single-time Intra-operative Intra-dermal Antibiotic Administration for Prevention of SSI
The purpose of the study is to study the incidence of surgical site infection when patients are given local versus parenteral antibiotics
- Trial name
- NCT04975945
- Testing
- Ceftriaxone Sodium
- Where
- India
- Sponsor
- The Grant Medical College & Sir J.J. Group of Hospitals
Surgical Site Infection
Delafloxacin IV and OS Administration Compared to Best Available Therapy in Patients With Surgical Site Infections
The purpose of this study is to assess the efficacy and safety of delafloxacin administered as IV and oral formulation in comparison with Best Available Therapy (BAT) in patients with superficial or deep incisional surgical site…
- Trial name
- DRESS (NCT04042077)
- Testing
- Delafloxacin, Vancomycin, Linezolid
- Where
- Italy
- Volunteers
- 268 people
- Sponsor
- Menarini Group
Wound Closure, Brain Tumor Adult
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
This research is studying a device already approved by the Food and Drug Administration (FDA) to treat wound closures. Researchers are studying a large group of people to continue to learn information about the safety of the…
- Conditions
- Wound Closure, Brain Tumor Adult, Spine, Neurovascular
- Trial name
- NCT07225101
- Testing
- STRATAFIX PDS and Monocryl suture
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Michigan
Skin Cancer, Skin Cancer Face
Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery
The purpose of this study is to compare surgical site infection rates for patients treated with Mohs micrographic surgery after bilateral nasal swab with povidone iodine versus standard treatment including the use of a…
- Conditions
- Skin Cancer, Skin Cancer Face, Malignant Cutaneous Adnexal Neoplasm
- Trial name
- NCT06207786
- Testing
- Povidone-Iodine Swabs, Staphylococcus nasal swab, Antibiotic
- Sponsor
- Mayo Clinic
Pulmonary Disease, Postoperative Respiratory Complications
Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography
The purpose of this study is to determine whether Electrical Impedance Tomography can be used as sensitive and specific predictor in the detection of postoperative pulmonary complications (e.g.
- Conditions
- Pulmonary Disease, Postoperative Respiratory Complications, Malignant Neoplasm of Stomach, Liver Diseases
- Trial name
- NCT02337673
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Johannes Gutenberg University Mainz
Surgical Site Infection, Groin Hernia
Prophylactic Antibiotics in Groin Hernioplasty
The role of prophylactic antibiotics in preventing surgical site infections (SSI) for clean procedures like groin hernia repair remains controversial.
- Conditions
- Surgical Site Infection, Groin Hernia, Hernioplasty
- Trial name
- NCT07111702
- Testing
- Cefazolin
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University