Clinical trials: Infection, Surgical Site
Head and Neck Cancer, Covid19
Impact of Covid-19 Pandemic on Management of Head and Neck Cancers
Since its emergence in late December 2019, the SARS-CoV-2 coronavirus has spread rapidly, causing a global health crisis. The disease caused by this highly contagious respiratory virus is called COVID-19.
- Conditions
- Head and Neck Cancer, Covid19, Patient Care
- Trial name
- VADS-Covid (NCT04704466)
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Surgical Site Infection, Surgical Complication
Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery
The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.
- Conditions
- Surgical Site Infection, Surgical Complication, Gynecologic Cancer
- Trial name
- NCT05210556
- Testing
- Diagnosed with Surgical Site Infection
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Colorectal Surgery
Safety and Efficacy of One Dose Prophylactic Antibiotic in Laparoscopic Colorectal Surgery
In colorectal surgery, the use of prophylactic antibiotics is recommended. The standard use of antibiotics for colorectal surgery is three doses.
- Trial name
- NCT01220661
- Testing
- Cefotetan
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- National Cancer Center, Korea
Surgical Wound Infection
Bacterial Colonization With and Without Iodophor-impregnated Adhesive Drapes in Hip Surgery: a Prospective, Randomized Trial
This is a prospective, randomized control trial evaluating the efficacy of iodophor-impregnated adhesive drapes for reducing bacterial count in hip surgery.
- Trial name
- NCT02919410
- Testing
- iodophor-impregnated adhesive drapes, No adhesive drapes
- Sponsor
- Rothman Institute Orthopaedics
Surgical Site Infection, Infection; Cesarean Section
Study to Evaluate DACC Dressings for the Prevention of Surgical Site Infections in Women Undergoing Caesarean Section.
Surgical site infections (SSIs) constitute an important medical and socioeconomic problem worldwide. Despite the fact that the risk factors for SSIs were identified and the continuously increasing medical knowledge in the fields…
- Trial name
- NCT02168023
- Testing
- DACC impregnated dressing, Standard surgical dressing
- Where
- Poland
- Volunteers
- 543 people
- Sponsor
- Medical University of Warsaw
Staphylococcus Aureus, Surgical Wound Infection
Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery
The most commonly identified organism for Surgical Site Infection (SSI) in orthopedic surgery is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known.
- Conditions
- Staphylococcus Aureus, Surgical Wound Infection, Orthopedic Disorder, Traumatology
- Trial name
- ISO (NCT03040960)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete
Thyroid Disease, Parathyroid Disease
Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery
The effectiveness of antimicrobial prophylaxis (AMP) for prevention of surgical site infection (SSI) following thyroid and parathyroid surgery remains uncertain.
- Trial name
- Ito-RCT1 (NCT01805856)
- Testing
- PIPC piperacillin sodium, CEZ, cefazolin sodium
- Where
- Japan
- Volunteers
- 2,164 people
- Sponsor
- Ito Hospital
Infection, Surgical Site
Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study
Patients randomly aligned in 2 groups.Vicryl plus sutures were used in group 1 for closing subperiostal flaps after dental implant surgeries and vicryl sutures were used in group 2.
- Trial name
- NCT03659344
- Testing
- Vicryl plus
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Emergency Surgery, Surgical Site Infections
Irrisept in Emergency General Surgery Patients
This is a single institution, randomized study conducted to determine if irrigation with Irrisept in emergency general surgery patients results in lower surgical site infections compared to normal saline irrigation.
- Trial name
- NCT07048899
- Testing
- Chlorhexidine, Normal Saline
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Surgical Wound Infection, Cross Infection
Reducing Intraoperative ESKAPE Transmission Through Use of a Personal Hand Hygiene System
The investigators hypothesize that the use of a personal hand hygiene system (SafeHavenTM) by anesthesia providers in the adult operating room, combined with a novel infectious pathogen tracking system (OR PathTrac) will decrease…
- Trial name
- ESKAPE (NCT04900298)
- Testing
- SafeHaven Automated Hand Hygiene Device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Postoperative Complications
The Effect of Telephone Nursing Education and Counseling Services Given to Satisfaction Level and Self-Care Strength
In the post-discharge period, it is important to follow the patients from home by telephone and to provide the necessary nursing education and counseling services, increasing the self-care powers of the patients, increasing their…
- Trial name
- NCT05487638
- Testing
- Nursing Education and Counseling Service Provided to Patients by Video Calling on the Phone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Postoperative Surgical Site Infections
Negative Pressure Wound Therapy Use to Decrease Surgical Nosocomial Events in Colorectal Resections
The purpose of this study is to determine, in patients who undergo an elective colorectal resection through a midline laparotomy incision, whether the use of negative pressure wound therapy (NPWT) applied to the site of the…
- Trial name
- NEPTUNE (NCT02007018)
- Testing
- Negative Pressure Wound Therapy, Usual Care of Surgical Wound
- Where
- 2 sites in Canada
- Volunteers
- 300 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Surgical Wound Infection
Comparison of Surgical Site Infection Rate Between Primary, Delayed Primary and Vacuum Assisted Closures.
The objective of the study is to compare infection rates between primary, delayed primary and vacuum assisted closures in contaminated and dirty/infected laparotomy wounds.
- Trial name
- NCT02649543
- Testing
- Primary Closure, Vacuum Assisted Closure, Delayed Primary Closure
- Where
- Mexico
- Volunteers
- 81 people
- Sponsor
- Eduardo Flores Villalba
Surgical Incision, Surgery--Complications
Zinc Oxide Versus Petrolatum Following Skin Surgery
Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this…
- Conditions
- Surgical Incision, Surgery--Complications, Surgical Wound, Surgical Site Infection
- Trial name
- NCT03561376
- Testing
- Topical zinc oxide vs. petrolatum post-surgical scars
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melissa Pugliano-Mauro
Post Operative Surgical Site Infection
Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA
The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections of tibial plateau and tibial pilon fractures at…
- Trial name
- TOBRA (NCT04597008)
- Testing
- Treatment group, Control group
- Where
- 41 sites in United States
- Volunteers
- 1,660 people
- Sponsor
- Major Extremity Trauma Research Consortium
Surgical Site Infection
Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections
Use of 2% chlorhexidine gluconate cloths pre-operatively and daily post-operatively jaw line to toes will decrease surgical site infections (SSI) by 30% when compared to patients who receive routine standard of care (use of…
- Trial name
- NCT02385708
- Testing
- 2% Chlorohexidine Gluconate Standard of Care, 2% Chlorohexidine Gluconate Chin to Toe
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Vanderbilt University
Surgical Site Infection
Intraoperative Oxygen Concentration on Incidence of Surgical Site Infection
Surgical site infections (SSI) are the most common healthcare-associated infections and sources of morbidity and over-mortality.
- Trial name
- NCT06108791
- Testing
- FIO2=0.8, FIO2=0.33
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Assiut University
Surgical Site Infection (SSI), Ileostomy Closure
Linear Versus Purse String Skin Closure at Loop Ileostomy Reversal.
This study is a randomized controlled trial designed to compare two commonly used skin closure techniques-linear closure and purse-string closure-after loop ileostomy reversal surgery.
- Conditions
- Surgical Site Infection (SSI), Ileostomy Closure, Surgical Technique Comparison
- Trial name
- NCT07573423
- Testing
- Linear Skin Closure, Purse-String Skin Closure
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Surgical Site Infection
Antibiotic Prophylaxis in Clean Surgery. Impact on Surgical Site Infection
This is a randomized control study of antibiotic uses in clean non prosthetic surgeries. One group will be given antibiotic prophylaxis, other will receive a placebo.
- Trial name
- NCT03595852
- Testing
- Cefazolin
- Where
- Rwanda
- Volunteers
- 138 people
- Sponsor
- University of Rwanda