Clinical trials: Infection, Surgical Site
Surgical Site Infections
Review of Surgical Site Infection Registration Routine at Surgery Departments in Sweden and Validation of One of the Used Routines
This study explores the routines of registration of surgical site infections (SSI) at different surgical centers in Sweden. It explores the sensitivity and specificity of the registration routines of SSI are at Halmstad County…
- Trial name
- NCT01971138
- Testing
- this is a survey
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Halmstad County Hospital
Diabetic Foot Ulcer, Venous Leg Ulcer
PLASOMA Ultimate Safety & Efficacy Study
The purpose of the PULSE study are the followingL A.To perform post market clinical follow up (PMCF) on safety and efficacy: 1. Safety: To confirm transient short-terms side effects and verify long-term/outstanding risks. 2.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Burn Wound
- Trial name
- PULSE (NCT04828304)
- Testing
- PLASOMA
- Where
- 6 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Plasmacure
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Surgical Wound Infection, Traumatic Wound Infection
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections
The goal of this Phase 1 clinical trial is to learn about the safety profile of Amicidin-β topical solution applied directly into infected surgical or traumatic wounds during a surgical procedure.
- Trial name
- NCT07379684
- Testing
- Amicidin-β topical solution - 15 mL, Amicidin-β topical solution - 50 mL, Standard of Care (SOC)
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Macro Biologics, Inc.
Hyperoxia
Hyperoxygenation in Anesthetized Children
This study is aiming at assessing the effect of inspired oxygen fraction during general anesthesia on children's lung mechanics and volume.
- Trial name
- OXPED (NCT02384616)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Walid HABRE
Orthopedic Surgery
Biofilm Formation and Antibiotic Sensitivity Patterns
Detection of bacteria that form biofilm and its sensitivity to antibiotics in patients with surgical site infection after orthopedic surgery.
- Trial name
- NCT05181163
- Testing
- swab
- Volunteers
- 100 people
- Sponsor
- Sohag University
Surgical Site Infection
Nasal Decolonization for Orthopedic Trauma Patients
Many surgical site infections are caused by bacteria that is transferred from a patient's nose to their open surgical wound. Some small studies have shown that putting povidone-iodine in a patient's nose reduces this risk.
- Trial name
- NCT04146116
- Testing
- intranasal povidone-iodine
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Iowa
Post-operative Complications, Surgical Site Infection
The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
The purpose of this study is to compare the post-surgical standard-of-care dressing to the Prevena™ Incision Management System in women undergoing Cesarean section surgery.
- Conditions
- Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
- Trial name
- NCT01450631
- Testing
- Prevena™ Incision Management System (PIMS), Standard-of-care Dressing
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- KCI USA, Inc
Surgery, Multiorgan Failure
The Influence of Nursing Technique Applied at the Central Venous Catheter Insertion Site Upon the Incidence of Infection
Assessing the impact of the nursing technique applied at the insertion site of the central venous catheter using hydrophilic methacrylate gel (HMG) and 2% Chlorhexidine (CHG) upon the incidence of inflammatory complications when…
- Conditions
- Surgery, Multiorgan Failure, Haematologic Disease
- Trial name
- NCT03875352
- Testing
- CHG technique, HMG technique
- Where
- Czechia
- Volunteers
- 221 people
- Sponsor
- University Hospital Ostrava
Surgical Wound Infection
Surgical Site Infections at a West Cameroon Hospital
Surgical site infections (SSI) constitute an important health concern in low and middle income countries, leading to prolonged hospital stay and increased costs.
- Trial name
- SSI Mbouo (NCT05018884)
- Testing
- Observation of surgical site infections
- Where
- Cameroon
- Volunteers
- 148 people
- Sponsor
- Christian Doll
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Obesity, Surgical Site Infections
Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery
The investigators aim to show that single use negative pressure dressings can decrease the rate of wound complications in obese women (BMI > 40 kg/m2) undergoing cesarean delivery at a tertiary medical center by randomizing women…
- Conditions
- Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
- Trial name
- NCT02799667
- Testing
- Standard Dressing, Negative Pressure Wound Therapy Dressing
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Surgical Site Infection, Surgical Procedures, Operative
Polihexanide SSIs Measures Bundle (PSMB) During Enhanced Recovery After Major Digestive Surgery
This is a randomized controlled, prospective, multicenter superiority trial with two parallel treatment groups and single blinding (local investigators performing postoperative follow up will be blinded for group allocation)…
- Trial name
- POSSIBLE (NCT06338163)
- Testing
- Polihexanide-based bundle, Standard bundle
- Where
- 3 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- Marco Catarci
Efficacy Povidone Soaked Suture in Reducing Surgical Site Infection
Title: Povidone-soaked Sutures Versus Ordinary Sutures for Reducing Surgical Site Infection
To determine efficacy of using 3 minutes povidone-soaked suture in reducing surgical site infection during wound closure in elective surgery.
- Trial name
- NCT05090176
- Testing
- povidone-soaked suture, ordinary suture
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Colon Cancer
Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis
This study is a randomized controlled trial conducted at University Medical Center Ho Chi Minh City to evaluate the role of mechanical bowel preparation (MBP) in patients undergoing laparoscopic right hemicolectomy with totally…
- Trial name
- UMC-Colprep (NCT07546565)
- Testing
- Mechanical Bowel Preparation, No mechanical bowel preparation
- Where
- Vietnam
- Volunteers
- 74 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Surgical Site Infections, Hypothermia
Feedback on Perioperative Temperature Management and Patient Outcomes: Three-arm Trial to Compare Feedback
The investigators aim to assess the impact of benchmarked and ranked feedback on anesthesiologists' perioperative temperature management and subsequent patient outcomes.
- Trial name
- NCT02414191
- Testing
- Benchmarked Feedback, Ranked Feedback
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Lung Neoplasm, Adult ALL
LUS to Assess Lung Injury After Lung Lobectomy
The purpose of the study is to assess whether lung ultrasound is able to detect lung injury after lung resection surgery.
- Conditions
- Lung Neoplasm, Adult ALL, Lung Injury, Lung Inflammation
- Trial name
- OPEN THORUS (NCT04755478)
- Testing
- Thoracotomy, VATS
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital General Universitario de Valencia
Site Infection
Incidence of Ssi After c.s
aim of the work is to evaluate adherence to preoperative , intraoperative, and postoperative infection preventive measures during cesarean section and to assess it s impact on the incidence of surgical site infection and maternal…
- Trial name
- NCT07476261
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Assiut University
Surgical Site Infection
The Use of Diluted Povidone Iodine Irrigation in Spine Surgery
The purpose of the study is to determine whether diluted Povidone Iodine solution used to irrigate surgical wounds during spine surgery decreases the incidence of surgical site infections.
- Trial name
- NCT01577524
- Testing
- Povidone-Iodine, Saline
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Attabib, Najmedden, M.D.
Surgical Site Infection
Continuous Antibiotic Prophylaxis in Colorectal Surgery
We propose to randomise patients due to undergo colorectal surgery to standard antibiotic prophylaxis or an interventional antibiotic prophylaxis regimen and assess surgical wound infection rates.
- Trial name
- Colo-Pro (NCT02445859)
- Testing
- Cefuroxime 4 hourly bolus
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Leeds