Clinical trials: Infection;Post Surg Procedure
Intraabdominal Abscess After Procedure
Specific Bile Microorganisms Caused Intra-abdominal Abscess on Pancreaticoduodenectomy Patients: Customized Antibiotics And Antifungal Medication May Be Necessary
Background Intra-abdominal abscess (IAA) is one of the most serious surgical infectious complications on pancreaticoduodenectomy (PD) patients.
- Trial name
- NCT05011630
- Testing
- Pancreaticoduodenectomy
- Volunteers
- 539 people
- Sponsor
- National Taiwan University Hospital
Wound Complication, Cardiac Surgery
Effectiveness of Topical Vancomycin in Reducing Sternal Wound Infections Post-Cardiac Surgery
Title: The Role of Vancomycin Powder in Reducing Sternal Wound Infections Following Cardiac Surgery: A Randomized Controlled Trial Introduction: Sternal wound infections (SWIs) are significant complications in cardiac surgery…
- Trial name
- NCT06651268
- Testing
- while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Liaquat National Hospital & Medical College
Surgical Site Infection, Antibiotics Prophylaxis
Cefuroxime vs Ceftriaxone for SSI Prevention in Neurosurgery
BACKGROUND: Surgical site infection (SSI) is potentially catastrophic in neurosurgical procedures, causing poor in-hospital outcomes in more than half of those affected and significantly increased length of hospital stay.
- Trial name
- NCT05398081
- Testing
- Cefuroxime (Zinnat®), Ceftriaxone (Rocephin®)
- Where
- Nigeria
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dr. Promise Tamunoipiriala Jaja
Post Operative Endophthalmitis
Effectiveness and Safety of 0.5% Moxifloxacin Hydrochloride Ophthalmic Solution in Perioperative Sterilization in Patients Undergoing Ophthalmic Surgery
This is a non-interventional, uncontrolled, prospective, multicenter, post marketing surveillance study.
- Trial name
- NCT05413980
- Testing
- Moxifloxacin hydrochloride ophthalmic solution
- Where
- 9 sites in India
- Volunteers
- 102 people
- Sponsor
- Novartis Pharmaceuticals
Surgical Wound Infection
Skin Perfusion After Abdominal Surgery
The purpose of this study is to evaluate the consequences of 3 selected surgical procedures on abdominal wall perfusion in order to help to reduce postoperative complication related to inadequate tissue perfusion.
- Trial name
- DIRTSURGERY (NCT03057249)
- Testing
- Dynamic infrared thermography (DIRT)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital of North Norway
Infection;Post Surg Procedure, Peritoneal Cancer
Post Splenectomy Infections After Surgery for Peritoneal Malignancies (OPSI)
The spleen is involved in maintaining immunity and plays an important role in the elimination of encapsulated bacteria and parasites.
- Trial name
- OPSI (NCT05718726)
- Testing
- Questionnaire, interview or observation study
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Pancreatic Cancer
Standard Versus Prolonged Antibiotic Prophylaxis After Pancreatoduodenectomy (SPARROW)
The goal of this multicenter randomized controlled trial is to evaluate the additional value of pre-emptive antibiotic treatment on clinically relevant organ/space surgical site infections (OSIs) in patients undergoing…
- Trial name
- SPARROW (NCT05784311)
- Testing
- Cefuroxime, Metronidazole
- Where
- 11 sites in Netherlands
- Volunteers
- 344 people
- Sponsor
- Leiden University Medical Center
Incisional Hernia, Ventral Hernia
Risk Factors for Mesh Infection After Abdominal Wall Reconstruction
Abdominal wall reconstruction (AWR) with mesh is the standard repair for ventral, incisional, parastomal and complex abdominal wall defects, but mesh-related infection remains one of its most serious complications - prolonging…
- Conditions
- Incisional Hernia, Ventral Hernia, Parastomal Hernia, Abdominal Wall Defect
- Trial name
- NCT07725718
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- Minia University
Infection Secondary to Surgical Procedure
Antimicrobial Efficacy of ALT005 Ophthalmic Prep Solution in Healthy Volunteers
This is an open-label, randomized, single-dose, placebo-controlled efficacy study to assess the antimicrobial efficacy of ALT005 ophthalmic prep solution following dermal administration in healthy volunteers.
- Trial name
- NCT01531699
- Testing
- ALT005 Ophthalmic Prep Solution, saline control, Betadine ophthalmic prep solution
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Altacor Ltd.
Surgical Wound Infection
Impact of Early Post-Operative Water Exposure on Complications of Cutaneous Surgeries
Patients are often counseled to keep a surgical wound dry for 2 to 3 days. The rationale is likely to decrease the risk of infection and bleeding. However, this has never been formally studied.
- Trial name
- NCT01773694
- Testing
- Early Water Exposure
- Where
- United States
- Volunteers
- 507 people
- Sponsor
- Milton S. Hershey Medical Center
Osteomyelitis
CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure
The study is a prospective cohort study of subjects where CERAMENT G was used as part of the surgical treatment of osteomyelitis in a single stage procedure.
- Trial name
- CERTITUDE (NCT06555848)
- Testing
- CERAMENT G
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- BONESUPPORT AB
Wound Infection and Wound Healing
Post-Surgery Wound Healing Tracking With MyHealthPal App
The investigators want to explore the use of a smartphone app that allows patients to take photos of their wounds in early stages of healing, so that clinicians can monitor wound-healing remotely with the assistance of an AI…
- Trial name
- NCT07391735
- Testing
- MyHealthPal App
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Brigham and Women's Hospital
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Aortic Valve Disease, Surgery--Complications
Immune Responsiveness and Outcome After Aortic Valve Surgery (Measure)
There is considerable morbidity and mortality associated with cardiac surgery. Currently little effort is made to quantify how well the immune system of an individual can cope with inflammation or infection to which they are…
- Conditions
- Aortic Valve Disease, Surgery--Complications, Immune System Disorder
- Trial name
- Measure (NCT04430972)
- Testing
- Aortic valve replacement
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Barts & The London NHS Trust
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Wound Infection Post-Traumatic, Wound Infection
Patient Education at Dismissal After Surgical Procedure
Can improvements in patient dismissal education materials reduce incidence of wound non-healing and infection.
- Conditions
- Wound Infection Post-Traumatic, Wound Infection, Wound Complication, Wound Breakdown
- Trial name
- NCT03815500
- Testing
- Enhanced Education
- Sponsor
- Mayo Clinic
Drug Effect, Rib Fractures
Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures
Rib fractures represent a common injury pattern this is highly associated with patient morbidity and mortality, as pain control remains a challenge.
- Conditions
- Drug Effect, Rib Fractures, Rib Trauma, Surgical Procedure, Unspecified
- Trial name
- NCT03305666
- Testing
- Liposomal bupivacaine injection, Bupivacaine indwelling catheter
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Denver Health and Hospital Authority
Dural Defect, Cerebrospinal Fluid Leak
Immiseal™ Dural Sealant Post-Market Registry Study
This is a multicentre, prospective, open-label, single-arm, observational, post-market clinical follow-up registry study designed to observe the safety and performance of the Immiseal™ Dural Sealant System when used as an adjunct…
- Conditions
- Dural Defect, Cerebrospinal Fluid Leak, Neurosurgical Procedures
- Trial name
- NCT07651826
- Where
- Latvia
- Volunteers
- 85 people
- Sponsor
- Medprin Regenerative Medical Technologies Co., Ltd.
Surgical Site Infection, Surgical Procedures, Operative
Polihexanide SSIs Measures Bundle (PSMB) During Enhanced Recovery After Major Digestive Surgery
This is a randomized controlled, prospective, multicenter superiority trial with two parallel treatment groups and single blinding (local investigators performing postoperative follow up will be blinded for group allocation)…
- Trial name
- POSSIBLE (NCT06338163)
- Testing
- Polihexanide-based bundle, Standard bundle
- Where
- 3 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- Marco Catarci
Cataract Surgery, Ocular Infections
Efficacy of EPD-09-25 for Eyelid Hygiene Before and After Eye Surgery.
This is an interventional, open-label, two-arms clinical trial, randomized 1:1 (EPD treatment or no eyelid hygiene treatment) in patients scheduled for eye surgery (cataract surgery).
- Trial name
- NCT07418333
- Testing
- EPD Eyelid wipes
- Volunteers
- 100 people
- Sponsor
- VISUfarma SpA