Clinical trials: Infection Control / Methods
Urinary Tract Infection, Kidney Failure
Healthy.io Method Comparison & User Performance Study
The objectives of the Healthy.io Method Comparison and User Performance Study are: 1. To evaluate the performance of Dip.io Device in comparison to the ACON U500 Mission® U500 Urine Analyzer. 2.
- Conditions
- Urinary Tract Infection, Kidney Failure, Diabetes
- Trial name
- NCT02785445
- Testing
- Dip.io Home Based Dipstick Analyzer, ACON U500 Mission® U500 Urine Analyzer
- Where
- 2 sites in United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Healthy.io Ltd.
Surgical Site Infection Following Cesarean Delivery
The Mepilex Cesarean Delivery Trial
The goal of this clinical trial is to learn whether using a silver-containing antimicrobial foam dressing (Mepilex Ag) can help prevent surgical site infections in patients undergoing cesarean delivery.
- Trial name
- MEPIDEL (NCT07066254)
- Testing
- Mepilex Ag Dressing, Standard Surgical Dressing (Telfa non-adhesive dressing, gauze, and Primapore adhesive bandage)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Appendicitis, Surgical Wound Infection
Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)
The goal of this clinical trial is to compare primary wound closure (PC) versus delayed primary closure (DPC) after standardized wound decontamination using the High-Efficiency Incision and Drainage with Irrigation (HIEDI)…
- Conditions
- Appendicitis, Surgical Wound Infection, Postoperative Complications, Wound Healing
- Trial name
- HIEDI-Yemen (NCT07688109)
- Testing
- Primary Closure with HIEDI, Delayed Primary Closure with HIEDI
- Where
- 3 sites in Yemen
- Volunteers
- 200 people
- Sponsor
- Sana'a University
Surgical Wound Infection
Safe Hands at the Sharp End- Implementing Aseptic Technique in the Operating Room
The aim of this integrated Knowledge Translation (iKT) study is to develop and test a multifaceted implementation intervention for feasibility, acceptability and effectiveness.
- Trial name
- NCT02983136
- Testing
- Dialogue and inter-professional learning
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Göteborg University
Whooping Cough
A Phase 1/2 Clinical Trial of a GamLPV, a Live Intranasal Bordetella Pertussis Vaccine
The study should be leaded as a randomized double-blind placebo-controlled comparative research of potency and safety of a GamLPV, a live intranasal Bordetella pertussis vaccine, using two dosing schedules and methods of…
- Trial name
- NCT04036526
- Testing
- Vaccine GamLPV
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
HPV Vaccination, Uptake Vaccination
PREVENT Pilot HPV - Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT06738355
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Utah
Respiratory Tract Infections (RTI), Meningitis
Immune-Mitochondrial Correction in Military Recruits
The goal of this clinical trial is to learn if a new immune-mitochondrial correction strategy works better than standard vitamins to prevent infections in young male military recruits during their first 6 months of service.
- Conditions
- Respiratory Tract Infections (RTI), Meningitis, Primary Prevention/Methods, Primary Prevention
- Trial name
- IMMU-MITO (NCT07622147)
- Testing
- Multivitamin/Mineral supplements, Sodium nucleinate combination
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MIPO Clinic
Spinal Cord Injuries, Neurogenic Bladder Disorder
Medico-economical Impact of the Brindley Neurosurgical Technique in France
Bladder dysfunction is a major problem in patients with complete spinal cord lesions. For patients presenting incontinence or risk for kidney, two major conventional alternatives are possible : conservative therapies (muscarinic…
- Conditions
- Spinal Cord Injuries, Neurogenic Bladder Disorder, Paraplegia, Quadriplegia
- Trial name
- BRINDLEY (NCT00221767)
- Testing
- Brindley technique (bladder system)
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Bordeaux
Cerebrospinal Fluid Leakage, Subdural
Study to Evaluate Safety & Effectiveness of Spinal Sealant
To evaluate a spinal sealant as an adjunct to sutured dural repair compared to standard of care techniques.
- Trial name
- NCT00444067
- Testing
- Spinal Sealant, Standard of Care
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Integra LifeSciences Corporation
Dental Plaque, Calculus, Dental
Dental Isolation Methods in Pediatric Patients
The purpose of this study is to collect, measure, and assess the environmental spatter produced during dental appointments under different isolation methods used in pediatric dentistry, to compare the effectiveness of aerosol…
- Conditions
- Dental Plaque, Calculus, Dental, Aerosol Disease
- Trial name
- NCT04430387
- Testing
- The saliva ejector, The high-volume evacuator, The DryShield
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Suture Techniques, Wound Closure Techniques
Small Bites Vs Large Bites Abdominal Midline Incisional Closure
The goal of this trial is to compare the effectiveness of small bite versus large bite abdominal incision closure in emergency settings. It will also evaluate the safety and outcomes of each technique.
- Conditions
- Suture Techniques, Wound Closure Techniques, Laparotomy/Standerds, Surgical Wound Dehiscence
- Trial name
- NCT07154277
- Testing
- Small bite closure, Large bite closure
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Dow University of Health Sciences
Hand Hygiene, Health Care Associated Infection
Building an Optimal Hand Hygiene Bundle
Hand hygiene is the single most effective practice in preventing the spread of hospital-acquired infections. Despite the strength of the evidence, hospital staff continue to sanitize their hands less than half of the time…
- Conditions
- Hand Hygiene, Health Care Associated Infection, Compliance
- Trial name
- NCT02223455
- Testing
- Hand Hygiene Signs
- Where
- 10 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabetic Foot, Gangrene; Limb
MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation
Toe amputation is a commonly performed operation for infection and/or ischaemia (tissue death due to lack of blood flow). However, a large number of patients having this surgery ultimately require further amputation due to poor…
- Conditions
- Diabetic Foot, Gangrene; Limb, Wound Infection, Wound Healing Delayed
- Trial name
- MetaMet (NCT05804565)
- Testing
- Bone Saw, Bone Cutter
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Hospital Galway
Pilonidal Sinus Disease, Sacrococcygeal Pilonidal Sinus
Primary Closure vs Open Technique for Pilonidal Sinus
The purpose of this randomized controlled trial is to compare two commonly used surgical techniques for the treatment of pilonidal sinus disease: excision with primary closure and excision with open (lay-open) technique.
- Conditions
- Pilonidal Sinus Disease, Sacrococcygeal Pilonidal Sinus, Chronic Infected Sinus Tract, Post-surgical Wound Healing
- Trial name
- NCT07311707
- Testing
- Primary Suturing of Surgical Wound, Open Surgical Wound Management
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Schistosomiasis
Introduction of Arpraziquantel Treatment for Schistosomiasis Control in Preschool-aged Children in Endemic Areas: A Small-scale Public Health Intervention Study
The proposed small-scale pilot studies are public health intervention studies implemented through established routine programs and services in the frame of the mass drug administration (MDA) campaigns in Côte d'Ivoire, Kenya and…
- Trial name
- ADOPTpilot (NCT06698510)
- Testing
- Arpraziquantel 150mg dispersible tablet
- Where
- 7 sites in Côte d’Ivoire, Kenya and 1 more
- Volunteers
- 18,500 people, healthy volunteers welcome
- Sponsor
- Peter Steinmann
Pancreas Neoplasms, Lymphatic Metastasis
Comparing of Modified Wet Suction Technique and Dry Suction Technique for EUS-FNA of Solid Occupying Lesions
The purpose of this study is to compare the diagnosis accuracy of modified wet suction technique and 5ml dry suction technique on solid occupying lesions.
- Conditions
- Pancreas Neoplasms, Lymphatic Metastasis, Neoplasm Metastases, Unknown Primary Neoplasm Metastasis
- Trial name
- NCT02789371
- Testing
- the first pass is made with 5ml suction technique, the first pass is made with modified wet suction technique
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Bin Cheng
Influenza
A Randomized, Controlled, Unblinded, Clinical Trial of the Acceptability and Efficacy of Non-Pharmaceutical Methods in Preventing Spread of Influenza Within the Family
The proposed study will evaluate whether the use of non-pharmaceutical methods, such as surgical masks, isolation of patients and personal hygiene, are acceptable and effective in preventing the spread of influenza within the…
- Trial name
- NCT00410176
- Testing
- sanitation and personal hygiene
- Volunteers
- 400 people
- Sponsor
- Ministry of Health, Israel
Rabies
Clinical Trial of Freeze-dried Human Rabies Vaccine (Without Serum Vero Cells)
This study was intended to explore the safety and immunogenicity of the test vaccine compared to the control vaccine. The trial consisted of two phases. Phase I used an open-ended design.
- Trial name
- NCT05969626
- Testing
- 5-dose group of test vaccine, 5-dose group of control vaccine, 4-dose A group of test vaccine
- Where
- 4 sites in China
- Volunteers
- 2,460 people, healthy volunteers welcome
- Sponsor
- Ningbo Rongan Biological Pharmaceutical Co., Ltd.
Incisional Hernia/Prevention and Control, Surgical Site Infection (SSI)
Comparison of Small-bite Versus Conventional Midline Fascial Closure in Abdominal Surgeries
This study investigates how different incision and fascial closure (suture) techniques used in abdominal surgery are associated with the development of incisional hernia, a common long-term complication after laparotomy.
- Trial name
- NCT07340918
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Candida Auris Infection, Candida Auris Colonization
Evaluation of Rapid Diagnostic Device for the Detection of Candida Auris
"Candida auris is an emerging fungus that can cause severe infections, particularly in hospitalized patients, and is often resistant to multiple antifungal treatments.
- Conditions
- Candida Auris Infection, Candida Auris Colonization, Nosocomial Infections
- Trial name
- DiagRaMIE Caur (NCT07253311)
- Testing
- NG-TestⓇ C.auris kit
- Where
- Greece
- Volunteers
- 554 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris