Clinical trials: Infection Post Op
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Vascular Postoperative Complications, Urological System Complication of Procedure
Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplantation
Globally there have been about 45,000 kidney transplants last year. Currently, the overall survival of renal transplant receptors is 95% in the first year and 85% at 5 years.
- Conditions
- Vascular Postoperative Complications, Urological System Complication of Procedure, Lymphocele, Postoperative Infection
- Trial name
- NCT01631448
- Testing
- Fibrin Glue
- Where
- 2 sites in Mexico
- Volunteers
- 152 people
- Sponsor
- Alejandro Gonzalez-Ojeda
Direct Costs Excluding Capital Equipment Purchase, Operator (Surgeon) Completed Questionnaire
Prostate Vaporization Techniques in Canadian Hospital
Kingston General Hospital is committed to upgrading the surgical treatment platform for benign prostate surgery. Vaporization Surgery, either laser-vaporization or electo-vaporization is becoming a "standard" of therapy for…
- Conditions
- Direct Costs Excluding Capital Equipment Purchase, Operator (Surgeon) Completed Questionnaire, Operative Parameters (Time, Bleeding Etc), Complications (Post-op Retention, Bleeding, Re-admission to Hospital, Infection Etc)
- Trial name
- NCT03495258
- Testing
- Clarion Evolve Laser Vaporization System, Olympus TURis Plasma Vaporization
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Queen's University
Cataract, Endophthalmitis
The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision).
- Trial name
- NCT00730938
- Testing
- cefuroxime
- Where
- Kenya
- Volunteers
- 45 people
- Sponsor
- Presbyterian Church East Africa Kikuyu Hospital
Cardiac Surgery, Infection, Postoperative Wound
Management Practices and the Risk of Infection Following Cardiac Surgery
The purpose of the study is to determine the best ways to prevent infections after heart surgery. Participation in the study will last at most 3 months after heart surgery.
- Conditions
- Cardiac Surgery, Infection, Postoperative Wound, Postoperative Wound Infection, Infections, Nosocomial
- Trial name
- NCT01089712
- Where
- 10 sites in United States, Canada
- Volunteers
- 5,158 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Infection
Postoperative Supplemental Oxygen in Liver Transplantation
The aim of this prospective randomized controlled trial is to evaluate the impact of high concentration supplemental postoperative oxygen therapy on short-term and long-term results of liver transplantation, particularly with…
- Trial name
- PSOLT (NCT02857855)
- Testing
- 80% fraction of inspired oxygen for 6 postoperative hours, 28% fraction of inspired oxygen for 6 postoperative hours
- Where
- Poland
- Volunteers
- 193 people
- Sponsor
- Medical University of Warsaw
Cesarean Section
The Effect of Forced Air Warming During Cesarean Section on Postoperative Infectious Morbidity
The purpose of this study will be to assess whether forced air warming decreases the rate of surgical site infections following cesarean section.
- Trial name
- NCT00696462
- Testing
- forced-air warming
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University
Post-Op Infection, Adherence, Patient
The Digital Incentive Spirometer (DIS): Improving Adherence to Incentive Spirometry
The purpose of the protocol is to assess how incentive spirometer data gathered via a smartphone platform can be utilized to improve participant adherence to prescribed incentive spirometer exercises in the post-operative period.
- Conditions
- Post-Op Infection, Adherence, Patient, Pulmonary Atelectasis, Incentive Spirometry
- Trial name
- DIS (NCT03686631)
- Testing
- Smartphone Arm
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Beth Israel Deaconess Medical Center
Tooth Extraction, Post-Op Complication
Antibiotic Therapy in Erupted Tooth Extractions
Evaluation of the efficacy of amox+clav and of a probiotic after tooth extraction. the aim is to evaluate efficacy of antibiotic therapy after tooth extractions in preventing infections as compared to no therapy, and efficacy of…
- Conditions
- Tooth Extraction, Post-Op Complication, Amoxicillin
- Trial name
- NCT04082598
- Testing
- Amoxicillin Clavulanate, Bifidobacterium longum and Lactoferrin
- Volunteers
- 165 people
- Sponsor
- Antonio Barone
Postoperative Infection Rates
Powder Topical Rifampicin on Reducing Infections After Neural Tube Defect Surgery in Infants
The correct timing and technique of neural tube defect (NTD) repairs significantly decreases the morbidity and mortality of NTD cases. However, infections related to the surgery are still common.
- Trial name
- NCT03198819
- Testing
- Local Rifampisin and İnrtravenous cefotaxime
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yuzuncu Yil University
Postoperative Infection
RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean Section
Background Women undergoing Caesarean Section (CS) have an increased risk of postpartum infections compared to women undergoing vaginal delivery. In Denmark the incidence of post-CS infections is 7-10%.
- Trial name
- APIPICS (NCT02009098)
- Testing
- Cefuroxime
- Where
- 3 sites in Denmark
- Sponsor
- Odense University Hospital
Surgery, Covid19
GlobalSurg-CovidSurg Week
Observational study to determine the optimal timing for surgery following SARS-CoV-2 infection and assess key global surgery indicators.
- Conditions
- Surgery, Covid19, Post-Op Complication
- Trial name
- NCT04509986
- Volunteers
- 1,000 people
- Sponsor
- University of Birmingham
Esophagectomy, Postoperative Complications
Infectious Complications After Esophagectomy
Infectious complications represent the most common postoperative adverse events following esophagectomy for cancer, such as pneumonia (15% of cases).
- Conditions
- Esophagectomy, Postoperative Complications, Infections, Pneumonia
- Trial name
- CIFO (NCT06911658)
- Where
- 2 sites in France
- Volunteers
- 1,029 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Postoperative Complications
Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery
This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery.
- Conditions
- Coronary Artery Disease, Postoperative Complications, Aortic Valve Stenosis, Mitral Valve Disease
- Trial name
- PREFER-CABG (NCT03574311)
- Testing
- Ferric carboxymaltose, Physiological saline
- Where
- Finland
- Volunteers
- 210 people
- Sponsor
- Turku University Hospital
Iron-deficiency, Postoperative Complications
Impact of Iron Deficiency on the Incidence of Postoperative Infections
Iron deficiency is a common state during the perioperative period. Data from literature do not allow us to conclude on how perioperative iron deficiency influences postoperative infections occurrence.
- Conditions
- Iron-deficiency, Postoperative Complications, Postoperative Infection
- Trial name
- CARIPO (NCT04994275)
- Testing
- no intervention, but presence of ID or not
- Where
- France
- Volunteers
- 413 people
- Sponsor
- University Hospital, Angers
Postoperative Infection
Safety of 1 g and 2 g of Cefazolin in Pediatric Subjects
This is a Phase 4, open-label, single-dose, parallel-group, multicenter, safety study of cefazolin (1 g or 2 g) in pediatric subjects between 10 and 17 years of age (inclusive) scheduled for surgery.
- Trial name
- NCT03231228
- Testing
- Cefazolin 1 g Infusion, Cefazolin 2 g Infusion
- Where
- 5 sites in United States
- Volunteers
- 61 people
- Sponsor
- B. Braun Medical Inc.
Organ Transplantation, Immunosuppressive Agents
Immunosuppressants to Postoperative Infection and Death
The goal of this observational study is to explore the different immunosuppressive agents and related outcomes in organ transplantation patients in Taiwan.
- Conditions
- Organ Transplantation, Immunosuppressive Agents, Cohort Study
- Trial name
- NCT06121804
- Testing
- Immunosuppressive Agents
- Where
- Taiwan
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Postoperative Infection, Lactate
Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes
Intra-abdominal infection is one of the most serious complications after pancreatic resection. The preventive use of antibiotics intraoperatively could reduce the incidence rate of postoperative intra-abdominal infection.
- Conditions
- Postoperative Infection, Lactate, Antibiotics
- Trial name
- NCT05052619
- Testing
- Preventive use of advanced antibiotics, Routine
- Where
- China
- Volunteers
- 297 people
- Sponsor
- Peking Union Medical College Hospital
Postoperative Infection
Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery
Currently there is little consensus regarding postoperative antibiotic prophylactic treatment and its effect on the postoperative infection rate after Cochlear implantation.
- Trial name
- NCT06177444
- Testing
- Antibiotic
- Where
- Denmark
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Abdominal Surgery, Colon Surgery
D-PLEX 310: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Subjects who are planned to undergo an abdominal (colon) surgery and who will meet the study entry criteria will be randomly divided into 2 groups: for half D-PLEX will be administered concomitantly with the standard of care…
- Conditions
- Abdominal Surgery, Colon Surgery, Post-Op Infection
- Trial name
- NCT03633123
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 8 sites in Israel
- Volunteers
- 202 people
- Sponsor
- PolyPid Ltd.