Clinical trials: Infection Surgical Wound
Esophageal Cancer, Postoperative Pulmonary Atelectasis
High Flow Nasal Cannula After Esophagectomy
This study will compare the effect of HFNC versus standard oxygen administration after elective esophagectomy for cancer.
- Conditions
- Esophageal Cancer, Postoperative Pulmonary Atelectasis, Postoperative Pneumonia, Postoperative Pneumothorax
- Trial name
- OSSIGENA1V (NCT05718284)
- Testing
- AIRVO2, STANDARD CARE
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- Cristian Deana
Sepsis
Preclinical Detection of Sepsis Early in Hospitalized Patients Following Surgery, Injury or Severe Illness
This clinical study is to evaluate a novel biomarker - CNA Rapid Sepsis Dx - to predict the development of sepsis in patients admitted to the hospital with non-sepsis conditions.
- Trial name
- Pre-SEPSIS (NCT04189549)
- Testing
- CNA Rapid Sepsis Dx
- Where
- 5 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Robert Ehrman
Ankle Fractures
Cryotherapy Reduces Time to Surgery and Local Complication in Patients With Ankle Fractures
Ankle fractures are common injuries and cryotherapy is routinely used to reduce pain, swelling and local skin complications, both before and after surgery. However, the results on ankle surgery are contradictory.
- Trial name
- Cryotherapy (NCT06396364)
- Testing
- Cryotherapy
- Where
- 2 sites in Italy
- Volunteers
- 169 people
- Sponsor
- Azienda Ospedaliera San Camillo Forlanini
Surgical Wound Infection, Hematoma
Comparing Outcomes Of Single Layer Versus Multilayer Leg Closure Techniques Following Great Saphenous Vein Harvesting For CABG
This study aims to address the knowledge gap by comparing the outcomes of single-layer and multi-layer leg closure techniques following great saphenous vein harvesting for Coronary artery bypass grafting. Research question: 1.
- Conditions
- Surgical Wound Infection, Hematoma, Seroma Following Procedure, Prolonged Hospital Stay
- Trial name
- CABG (NCT07355452)
- Testing
- Multi-layer closure (MLC), singlelayer closure for leg wound
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Surgical Wound Infection
Surgical Site Infections at a West Cameroon Hospital
Surgical site infections (SSI) constitute an important health concern in low and middle income countries, leading to prolonged hospital stay and increased costs.
- Trial name
- SSI Mbouo (NCT05018884)
- Testing
- Observation of surgical site infections
- Where
- Cameroon
- Volunteers
- 148 people
- Sponsor
- Christian Doll
Postoperative Hernia
Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR)
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Trial name
- (PROTOP-PAR) (NCT05508152)
- Testing
- Wound irrigation with amoxicillin-clavulanate in saline solution, Wound irrigation with a saline solution
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital de Granollers
Anti-bacterial Agents, Pharmacokinetics
The Expected Advantage of Administering Prophylactic Antibiotics Using Target- Concentration Controlled Infusion
Preoperative antimicrobial prophylaxis is a key element for the prevention of surgical site infection, the most common type of nosocomial infection in surgical patients.
- Conditions
- Anti-bacterial Agents, Pharmacokinetics, General Surgery
- Trial name
- NCT05253339
- Testing
- target-controlled infusion (one of the administration methods), Standard administration method
- Where
- South Korea
- Volunteers
- 2,494 people
- Sponsor
- Asan Medical Center
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Surgical Procedure, Unspecified, Soft Tissue Infections
Three-dimensional Bone Regeneration Using Custom-made Meshes With and Without Collagen Membrane
The presence of alveolar ridge deficiencies is considered major limitation to achieve an implant-prosthetic restoration with high aesthetics and stability over time.
- Conditions
- Surgical Procedure, Unspecified, Soft Tissue Infections, Surgical Wound Dehiscence, Bone Density
- Trial name
- NCT04286334
- Testing
- Bone augmentation with cad-cam laser-sintered mesh
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- GBR Academy
Colorectal Cancer, Lung Cancer
The Effects of Preoperative Bevacizumab on Perioperative Complications
This is a nationwide multicenter,retrospective,observational real-world study. 1. To assess the risk of perioperative complications in patients with tumor who received bevacizumab prior to unexpected operation. 2.
- Conditions
- Colorectal Cancer, Lung Cancer, Operation Wound; Infection, Bevacizumab
- Trial name
- NCT04788381
- Testing
- Bevacizumab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Surgical Infection, Cesarean Section Wound
Evaluation of Surgical Site Infection After Cesarean Section
This study aims to investigate surgical site monitoring after cesarean section using a mobile application currently being developed.
- Trial name
- NCT07205939
- Testing
- Mobile Application usage
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sibel Bulut Haklı
Infection, Surgical Site Infection
Changing of Dressing for Periprosthetic Joint Infection in Total Knee Arthroplasty
The primary aim of the study is to compare two methods for a relationship with total knee infection: regular changing of dressings and not changing dressings.
- Conditions
- Infection, Surgical Site Infection, Prosthetic Infection, Wound Infection
- Trial name
- NCT04346875
- Testing
- Regularly changing of dressing, No application
- Volunteers
- 842 people
- Sponsor
- Bezmialem Vakif University
Postoperative Wound Infection, Postoperative Complications
Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study)
This is a prospective randomized, controlled, unblinded, interventional feasibility study to evaluate if showering with post operative drains in place leads to an increase in complications.
- Conditions
- Postoperative Wound Infection, Postoperative Complications, Surgical Site Infection, Drain Site Complication
- Trial name
- SHOWER (NCT04725916)
- Testing
- Showering, Restriction of Showering
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Sean Devitt
Wound Complications, Wound Infection
A Study to Evaluate a Quality Improvement Intervention to Reduce Wound Separation Rates in Obese Gynecologic Oncology Service Patients Undergoing Abdominal Surgery
Approximately 500,000 surgical site infections occur annually in the US. These lead to worse patient quality of life, more outpatient and emergency room visits, readmissions and home services, with an estimated increase in costs…
- Conditions
- Wound Complications, Wound Infection, Wound Separation
- Trial name
- NCT02071251
- Testing
- Prospective wound complication protocol
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Washington University School of Medicine
Surgical Site Infection
Supplemental Oxygen and the Risk of Surgical Site Infection
This is a study to see whether increasing the oxygen concentration during and after a cesarean section decreases the infection rate.
- Trial name
- PORSSI (NCT00876005)
- Testing
- Oxygen by mask
- Where
- United States
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- Santa Clara Valley Health & Hospital System
Surgical Wound Infection, Cesarean Wound; Dehiscence
Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time
It is a randomized, single-blind clinical trial, whose population to be studied will be randomized patients with a diagnosis of dehiscence and infection of a cesarean surgical wound who meet the inclusion and exclusion criteria.
- Trial name
- SAGRA (NCT06477770)
- Testing
- Clorhexidine soap, Sucrose
- Where
- Honduras
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Abscess, Wound Infection
Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections
To compare the efficacy of treatment with a single dose of dalbavancin 1500 mg to treatment with a two dose regimen of dalbavancin (1000 mg on Day 1 followed by 500 mg on Day 8) in participants with known or suspected…
- Conditions
- Abscess, Wound Infection, Surgical Site Infection, Cellulitis
- Trial name
- NCT02127970
- Testing
- Dalbavancin
- Where
- 78 sites in United States, Bulgaria and 10 more
- Volunteers
- 698 people
- Sponsor
- Durata Therapeutics Inc., an affiliate of Allergan plc
Head Trauma, Polytrauma
Comparative Study for the Validity of Various Severity Scoring System
Scoring systems for use in intensive care unit (ICU) patients have been introduced and developed over the last 30 years. They allow an assessment of the severity of disease and provide an estimate of in-hospital mortality
- Conditions
- Head Trauma, Polytrauma, Pre-Eclampsia, Sepsis
- Trial name
- NCT04683094
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Surgical Wound Infection
48 Hours After Surgery Shower Patient's Wound Infection Rate, Pain Score, Patient Satisfaction and Cost.
Background and Purpose:The level of the surgical wound healing of the epidermis takes 6-12 hours, and the peak period of 48 hours to achieve healing.The traditional postoperative wound care was every 1-3 days clean with saline…
- Trial name
- NCT01846598
- Where
- Taiwan
- Volunteers
- 444 people
- Sponsor
- National Taiwan University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.