Clinical trials: Infection Surgical Wound
Diabetes, Hyperglycemia
The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery
The purpose of this study was to investigate the effects of three different glycemic treatment conditions (tight, conventional, and standard) in the intraoperative period on: 1) postoperative surgical site infections, and 2)…
- Conditions
- Diabetes, Hyperglycemia, Surgical Site Infection
- Trial name
- NCT01831154
- Testing
- Tight Glycemic, Conventional Glycemic, Standard Glycemic
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- James A. Haley Veterans Administration Hospital
Bacterial Infections, Antibiotic Resistant Infection
Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan
The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.
- Conditions
- Bacterial Infections, Antibiotic Resistant Infection, Surgical Site Infection
- Trial name
- NCT05106803
- Testing
- ciprofloxacin
- Where
- Jordan
- Volunteers
- 24 people
- Sponsor
- Yarmouk University
Infection, Bacterial, Wound Infection
DACC in the REduction of Surgical Site INfection
Surgical site infection is an infection at a place in the body where surgery has taken place, and has been reported in around 5% of people undergoing an operation. In vascular surgery, infection rates are as high as 30%.
- Conditions
- Infection, Bacterial, Wound Infection, Wound Infection, Surgical, Surgical Incision
- Trial name
- DRESSINg (NCT02992951)
- Testing
- DACC-Coated Post Operative Dressing
- Where
- United Kingdom
- Volunteers
- 722 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Surgical Site Infections, ARSC Motivation Model
The Effect of an ARCS Model-Based Escape Room Simulation on Nursing Students' Knowledge, Motivation, and Self-Efficacy Regarding Surgical Site Infections
The study is designed as a randomized controlled trial with an experimental and control group, using a pre-test, post-test, and follow-up test design.
- Conditions
- Surgical Site Infections, ARSC Motivation Model, Escape Room Simulation
- Trial name
- NCT07551973
- Testing
- Escape Room Simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Surgical Wound Infection, Wound; Abdomen, Abdominal Wall
Surgical Site Infection Rate After Intra-Abdominal Surgery Using Negative Pressure Wound Therapy at Initial Closure
The goal of this study is to present a large single-institution experience reporting surgical site infection rates in patients who have undergone intra-abdominal surgery followed by wound closure with Negative Pressure Wound…
- Conditions
- Surgical Wound Infection, Wound; Abdomen, Abdominal Wall, Surgery
- Trial name
- NCT01924884
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Johns Hopkins University
Peritonitis, Surgical Site Infection
NPWT vs Primary Closure in SSI Prevention for Emergency Laparotomies for Peritonitis
The study aims to evaluate the efficacy of negative pressure wound therapy (NPWT) compared with primary closure (PC) in surgical site infection (SSI) prevention for laparotomy for peritonitis.
- Conditions
- Peritonitis, Surgical Site Infection, Infections, Wound Infection
- Trial name
- PRISTINE (NCT05684198)
- Testing
- subcutaneous NPWT
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Sternal Fracture, Sternal Wound Infection
Sternal Wound Infection in Patients Undergone Sternal Fixation Using Locking Compression Plates
Sternal Wound Infection (SWI) in open heart surgery is one of the most annoying and avoidable complications that one encounters during work.
- Conditions
- Sternal Fracture, Sternal Wound Infection, Surgical Site Infection
- Trial name
- NCT05040399
- Testing
- Locking Compression Plates, Sternal Wires
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Assiut University
Wounds and Injuries
Effect of Leukoreduced Blood Transfusions on Infection Following Trauma
The purpose of this study is to determine if leukoreduced blood transfusions reduce the risk of infection following trauma. Specifically, the investigators intend to evaluate whether there are clinically relevant differences in…
- Trial name
- NCT00135291
- Testing
- Leukoreduced blood transfusion
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Surgical Wound Infection
Prophylactic Negative Wound Pressure Therapy (PICO-7) Following Groin Incisions in Vascular Surgery (PICO-Vasc Study)
Comparison between waterproof sterile dressing OPSITE Post-Op Visible, Smith \& Nephew, UK and PICO-7, Smith \& Nephew, UK in terms of inguinal surgical wound infection and complications after lower limb revascularization.
- Trial name
- PICO-Vasc (NCT04840576)
- Testing
- Regular waterproof sterile dressing., Prophylactic Negative Pressure Dressing
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Corporacion Parc Tauli
Cesarean Section, Surgical Wound
To Explore the Effectiveness and Feasibility of HERADERM Hydrogel Wound Dressing on Caesarean Section Surgical Site
The wound of cesarean section involves multiple layers of tissue and often cause significant postoperative pain. The epidermal wound typically heals within 1 to 2 weeks after surgery.
- Conditions
- Cesarean Section, Surgical Wound, Surgical Wound Infection, Wounds and Injuries
- Trial name
- NCT06558240
- Testing
- HERADERM Hydrogel Wound Dressing (Sterile)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Diverticulitis, Surgical Site Infection
Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial
The goal of this observational study is to learn if a new surgical technique, called the NICE procedure, is as safe as standard methods for treating benign left-sided colon and rectal diseases in adults.
- Conditions
- Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery
- Trial name
- NCT06957236
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Methodist Hospital Research Institute
Chlorhexidine Gluconate Cloths, Infection; Cesarean Section
STRIPES Study: Study To Reduce Infection Post cEsarean Section
The objective of this study is to determine if the use of chlorhexidine gluconate cloths prior to cesarean section reduce the rate of infectious morbidity (i.e. surgical site infections, endometritis).
- Conditions
- Chlorhexidine Gluconate Cloths, Infection; Cesarean Section, Infectious Morbidity, Surgical Site Infections
- Trial name
- NCT02402907
- Testing
- 2% chlorhexidine gluconate (CHG) cloth
- Where
- United States
- Volunteers
- 1,356 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Surgical Wound Infections, Colorectal Surgery
Subcuticular Continuous Suture Versus Skin Staples to Reduce Surgical Site Infections in Colorectal Surgery Patients
A comparison of skin closure techniques (standard skin closure with staples versus a continuous (subcuticular) absorbable suture), to determine if this changes the rate of post operative wound infections in elective colorectal…
- Trial name
- NCT02143336
- Testing
- subcuticular suture, Skin staples
- Where
- 2 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Surgical Site Infection
Study of the Incidence of Surgical Site Infections Developed by Patients Hospitalized in the Wards of a Large Teaching Hospital in Rome, Italy
The surgical departments of the hospital were included in the study on a rotational basis over a period of 5 months. All patients undergoing surgery during this period were enrolled in the study.
- Trial name
- NCT05788575
- Testing
- surgery
- Where
- Italy
- Volunteers
- 5,424 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgical Site Infections
Continuous v Bolus Infusion of Cefazolin During Ventral Hernia Repair
Patients undergoing an elective ventral hernia repair will be randomly assigned to receive either bolus infusion or continuous infusion of the cefazolin as the prophylactic antibiotic.
- Trial name
- NCT02666365
- Testing
- Bolus infusion of Cefazolin, Continuous infusion of Cefazolin
- Sponsor
- Milton S. Hershey Medical Center
Acute Appendicitis
Perioperative Hyperoxygenation and Wound Site Infection Following Surgery for Acute Appendicitis
Patients undergoing open appendectomy for acute appendicitis were enrolled in a randomized prospective study.
- Trial name
- NCT01002365
- Testing
- Oxygen delivery, Oxygen administration
- Where
- Israel
- Sponsor
- Western Galilee Hospital-Nahariya
C.Surgical Procedure; Cardiac
Acute Normovolemic Hemodilution in High Risk Cardiac Surgery Patients.
Transfusions are one of the most overused treatments in modern medicine, and saving blood is one important issue all around the world.
- Trial name
- ANH (NCT03913481)
- Testing
- Acute normovolemic hemodilution, Standard care
- Where
- 32 sites in United States, Bahrain and 9 more
- Volunteers
- 2,000 people
- Sponsor
- Università Vita-Salute San Raffaele
Infection, Surgical Site
Negative Pressure Therapy After Infected Mesh Removal.
Chronic mesh infection mesh is a complication with leads to a long hospital stays, reoperation and admissions through emergency department.
- Trial name
- ICROMA (NCT05247086)
- Testing
- Negative pressure therapy
- Volunteers
- 94 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Presence of Ileostomy
Need for Subcutaneous Wound Drains in Ileostomy Reversal
The purpose of this study is to find out whether the insertion of subcutaneous wound drains has an influence on postoperative hospital stay in ileostomy reversal.
- Trial name
- DRASTAR (NCT01050686)
- Testing
- insertion of subcutaneous wound drain, no insertion of subcutaneous wound drain
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Charite University, Berlin, Germany
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