Clinical trials: Infection and Inflammatory Reaction
Catheter Infection
Local Inflammation Does Not Correlate With Bacterial Colonization and Contamination of Perineural Catheters
The aim of this study was to investigate the influence of alcoholic skin disin-fection before PNC (perineural catheter)-removal on the detection of bacteria on the subcutaneous part of the PNC or on the tip.
- Trial name
- NCT02599181
- Testing
- propanol-biphenol: Kodan
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Sepsis
EARLY-MYO-SEPSIS Registry
The diagnosis and pathophysiology of sepsis-induced cardiac dysfunction remain unknown. This registry is to evaluate characteristics of sepsis patients by multi-modalities imaging, including echocardiography, cardiovascular…
- Trial name
- NCT04513795
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Gingivitis
Effects on Tablets Containing Probiotic Candidate Strains
The aim of the study is to investigate the effect of tablets containing probiotic candidate strains, on gingival inflammation and the levels of selected pro- and anti-inflammatory cytokines in gingival crevicular fluid (GCF).
- Trial name
- NCT02633345
- Testing
- Probiotic tablets
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Copenhagen
Sepsis
Clinical Evaluation of e- Ab Sensor - Based Real-time Diagnosis of Serum Procalcitonin Level
The purpose of this study is to develop a real-time diagnostic technique with e- Ab sensor for serum PCT level measurement will offer a test with lower cost, and increase the applicability of serum Procalcitonin (PCT) level in…
- Trial name
- NCT01388114
- Testing
- Electrosensing Antibody Probe System (e- Ab sensing)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
The Efficacy and Safety for Super High-flux Dialyzer in Case of Sepsis in ESKD, End Stage Kidney Disease (ESRD)
Comparing Super High-flux and High-flux Dialyzer Performance Among Hemodialysis Patient With Sepsis : a Randomized Control Trial
Comparing the efficacy of superhigh-flux dialyzer with high-flux dialyzer in ESKD patient who have sepsis to improve mortality and sepsis outcome, an open label randomized control trial.
- Conditions
- The Efficacy and Safety for Super High-flux Dialyzer in Case of Sepsis in ESKD, End Stage Kidney Disease (ESRD), Sepsis
- Trial name
- NCT06989892
- Testing
- Super High-flux dialyzer (Elisio 19HDx), High-flux dialyzer (Elisio 19H)
- Where
- Thailand
- Volunteers
- 202 people
- Sponsor
- Navamindradhiraj University
Sepsis, Bacteriemia
Safety and Efficacy of Immages System in Patients Recieving IV Therapy
The study will evaluate the functionality of IMMAGES , an intravenous infusion device system, in patients hospitalized in Bait Balev hospital.
- Conditions
- Sepsis, Bacteriemia, CHF
- Trial name
- IV (NCT02020811)
- Testing
- Sentinel
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- PRo-IV
Cancer Pediatric, Neutropenia
Safety of Acupuncture and Intracutaneous Needles in Pediatric Cancer Patients: a Retrospective Study (ACUSAFE2021)
This study aims to demonstrate the safety of intracutaneous needles in pediatric cancer patients. For this, a two-year retrospective study will be carried out to determine the incidence of adverse effects related to acupuncture…
- Conditions
- Cancer Pediatric, Neutropenia, Thrombocytopenia, Bacteremia
- Trial name
- ACUSAFE2021 (NCT05585463)
- Testing
- acupuncture
- Where
- Spain
- Volunteers
- 460 people
- Sponsor
- Fundació Sant Joan de Déu
Sepsis
The Ohio State University Sepsis Registry
Specific Aim #1: To collect follow-up information about patients with sepsis in the OSUMC MICU who survive to hospital discharge for future retrospective IRB-approved studies.
- Trial name
- NCT00837421
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Ohio State University
AKI - Acute Kidney Injury
Renal Cell Arrest and Damage Biomarkers in Progression and Outcome of Septic AKI
The aim of the current study is to assess the predictive value of renal cell arrest biomarkers (urinary TIMP2 and IGFBP7), renal damage biomarkers (urinary KIM-1) and microscopic examination of urinary sediment in progression and…
- Trial name
- NCT06064487
- Testing
- renal cell arrest and damage biomarkers assessment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Invasive Candidiasis, Candidemia
Micafungin Versus Fluconazole in the Treatment of Invasive Candidiasis and Candidemia
To determine the efficacy and safety of micafungin (FK463) versus fluconazole (Diflucan) in treating patients with invasive candidiasis or candidaemia
- Trial name
- NCT00189709
- Testing
- Micafungin, fluconazole
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Astellas Pharma Inc
Sepsis
Ubiquinol (Reduced COQ10) for Patients With Sepsis
This study aims to determine if Ubiquinol (reduced form of COQ10) will attenuate mitochondrial injury and decrease inflammatory response in patients suffering from sepsis.
- Trial name
- NCT01948063
- Testing
- Ubiquinol
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Hemoperfusion, Sepsis
EAA-Guided AN69-oXiris and PMX-HP Therapy in Septic Patients
Sepsis and septic shock are life-threatening conditions in which the body's response to infection can cause dangerously low blood pressure and organ failure.
- Conditions
- Hemoperfusion, Sepsis, ICU, Endotoxin Levels
- Trial name
- NCT07788144
- Testing
- Adsorptive Hemofilter for Continuous Renal Replacement Therapy, Polymyxin B-Immobilized Hemoperfusion Cartridge
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyoung Moo Im
Bronchopulmonary Dysplasia, Preterm Infant Development
PremaBiom: Metatranscriptomics of the Respiratory Microbiome to Predict the Occurrence of Bronchopulmonary Dysplasia in Preterm Infants
The goal of this clinical trial is to understand the impact of respiratory microbiome maturation in respiratory health of preterm infants under 32 gestational weeks.
- Conditions
- Bronchopulmonary Dysplasia, Preterm Infant Development, Asthma Childhood, Bronchiolitis
- Trial name
- PremaBiom (NCT07411261)
- Testing
- Nasal swab, blood sampling, Mother milk sampling
- Where
- 6 sites in France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Caen
Hepatitis B Infection, Congenital Malformation
Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission
Immunoprophylaxis with two hepatitis B vaccinations following the hepatitis B immune globulin (HBIg) and hepatitis B vaccine at birth is largely effective in protecting infants from hepatitis B virus (HBV) infection.
- Conditions
- Hepatitis B Infection, Congenital Malformation, Birth Defect, Viremia
- Trial name
- NCT03476083
- Testing
- Tenofovir Disoproxil Fumarate (TDF) 300 mg oral daily.
- Where
- 7 sites in China
- Volunteers
- 280 people
- Sponsor
- New Discovery LLC
Sepsis, AKI
Effect of Antibiotic Choice On ReNal Outcomes (ACORN)
Sepsis is one of the most common causes of acute illness and death in the United States. Early, empiric broad-spectrum antibiotics are a mainstay of sepsis treatment.
- Conditions
- Sepsis, AKI, Neurotoxicity
- Trial name
- ACORN (NCT05094154)
- Testing
- anti-pseudomonal cephalosporin, anti-pseudomonal penicillin
- Where
- United States
- Volunteers
- 2,634 people
- Sponsor
- Vanderbilt University Medical Center
Sepsis, Shock
Assessment of Transcutaneous Oxygen Tension/Oxygen Challenge Test in Intensive Care Unit (ICU) Patients
The lack of subcutaneous partial pressure of oxygen (PO2) rise in response to high fraction of inspired oxygen (FiO2), called the "oxygen challenge test (OCT)", was associated with higher morbidity and mortality in human…
- Trial name
- ICUPtO2OCT (NCT01174966)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Infection
Effectiveness of Topical Glycerine Sulphate Paste, Hirudoid Cream and Nil Application on Superficial Phlebitis
The aim of the interventional study is to compare the different treatment modalities in reducing erythema size and rate of resolving phlebitis.
- Trial name
- NCT01226069
- Testing
- Glycerine Magnesium sulphate paste, Mucopolysaccharide polysulphate, No application
- Where
- Singapore
- Volunteers
- 147 people
- Sponsor
- Tan Tock Seng Hospital
Sepsis
Evaluation of biomArkers for Quick SEpsis Diagnosis - ErASED Study
Since the "Sepsis-3" consensus statement in 2016, sepsis has been defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Recognition of sepsis is mostly based on clinical criteria.
- Trial name
- NCT07655154
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Urinary Tract Infection, Fluoroquinolone
Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin
The information collected will optimize the management of patients with urinary tract infections with secondary bacteremia, primarily with gram negative bacteria especially Escherichia coli.
- Conditions
- Urinary Tract Infection, Fluoroquinolone, Bacteremia
- Trial name
- NCT00414362
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Pittsburgh
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.