Clinical trials: Infections, Coronavirus
Covid-19
Correlation of Antibody Response to COVID-19 Vaccination in Pregnant Woman and Transplacental Passage Into Cord Blood.
The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV.
- Trial name
- NCT06259656
- Testing
- COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vachira Phuket Hospital
Severe Acute Respiratory Syndrome Coronavirus 2
An Exploratory Study of ADR-001 in Patients with Severe Pneumonia Caused by SARS-CoV-2 Infection
Safety and efficacy of ADR-001 are evaluated in Patients with Severe Pneumonia caused by SARS-CoV-2 infection.
- Trial name
- COVID-19 (NCT04522986)
- Testing
- Mesenchymal stem cell
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Rohto Pharmaceutical Co., Ltd.
SARS-CoV-2, Covid19
National Survey Concerning Vaccination Against COVID-19 in Nursing Homes and Long-Term Care Units
The COVID-19 pandemic is a challenge for the French healthcare system, particularly among the elderly due to their particular vulnerability to the serious consequences of the disease, with an estimated mortality rate of around…
- Trial name
- VACOVID-SENIOR (NCT04779541)
- Testing
- observation
- Where
- France
- Volunteers
- 323 people
- Sponsor
- University Hospital, Angers
SARS-CoV Infection
Efficacy of L. Plantarum and P. Acidilactici in Adults With SARS-CoV-2 and COVID-19
Clinical research focused to evaluate the effect as coadyuvant of a combination of L. plantarum and P. acidilactici in adults positive for SARS-CoV-2 with mild clinical COVID-19 symptoms.
- Trial name
- NCT04517422
- Testing
- Probiotics
- Where
- Mexico
- Volunteers
- 300 people
- Sponsor
- AB Biotics, SA
COVID-19
INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19
INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19 The purpose of this Interventional study is to investigate the effect of high frequency chest wall oscillation in hospitalized COVID-19…
- Trial name
- HFCWO IN COVID (NCT05705661)
- Testing
- HIGH FREQUENCY CHEST WALL OSCILLATION
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Covid-19 Infection
Awake Pronation for Covid-19 Treatment
Observational studies have shown that prone position (PP) in spontaneously breathing patients, may improve oxygenation in individuals with Acute Respiratory Failure (ARF), due to Covid-19 infection.
- Trial name
- NCT04667286
- Testing
- Prone Position (PP)
- Where
- 3 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Coronavirus, Pneumonia
Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19)
There is a high risk of transmission of COVID-19 to healthcare workers. In a recent cohort, 29% of the patients hospitalized were healthcare workers.
- Conditions
- Coronavirus, Pneumonia, Oxygen Toxicity
- Trial name
- NCT04320056
- Testing
- Standard administration of oxygen flow, Automated oxygen administration - FreeO2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Laval University
Vaccine Hesitancy
Motivational Interviewing for Vaccine Uptake in Latinx Adults
The goal of this clinical trial is to test whether modified behavioral health services, integrating motivational interviewing, will reduce vaccine hesitancy and increase uptake for the COVID-19 and influenza vaccines among Latinx…
- Trial name
- MIVacuna (NCT06062056)
- Testing
- EHR alert, Motivational Interviewing, Warm hand off to nurse
- Where
- 2 sites in United States
- Volunteers
- 3,698 people, healthy volunteers welcome
- Sponsor
- Boston College
Covid19, Post-COVID / Long-COVID
Post-coronavirus Disease-2019 Fatigue
Background: COVID-19 is consistently spreading throughout the world, and the number of recovered patients is steadily increasing.
- Trial name
- NCT04851561
- Testing
- Cardiopulmonary stress test (CPET)
- Where
- Israel
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Covid19
Phase 1 Study to Assess Safety, Tolerability, PD, PK, Immunogenicity of IV NTR-441 Solution in Healthy Volunteers and COVID-19 Patients
This first-in-human clinical study is a Phase 1a/ 1b, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, and PK/PD of NTR-441 in healthy subjects and patients with COVID-19 after single…
- Trial name
- NCT04941183
- Testing
- NTR-441
- Where
- 4 sites in Austria, Ukraine
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Neutrolis
COVID-19
Reduction in COVID-19 Infection Using Surgical Facial Masks Outside the Healthcare System
In the current COVID-19 pandemic with coronavirus, SARS-COV2, the Danish Health Authorities recommend using facial masks in the health care system when handling patients presumed or proven to be infected with the virus.
- Trial name
- NCT04337541
- Testing
- Surgical facial mask
- Where
- Denmark
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Covid19
Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection
The COVID-19 infection primarily manifests itself as a respiratory tract infection, although new evidence indicates that this disease has systemic involvement involving multiple systems including the cardiovascular, respiratory…
- Trial name
- HEPMAB (NCT04600141)
- Testing
- Tocilizumab, Heparin - Therapeutic dosage, Heparin - Prophylactic dosage
- Where
- 3 sites in Brazil
- Volunteers
- 308 people
- Sponsor
- University of Sao Paulo
SARS-CoV-2 (Covid19)
Safety and Efficacy of Trans Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects
This study will assess the safety and efficacy of TSC as a treatment for participants who are infected with SARS-CoV-2 (COVID-19).
- Trial name
- NCT04573322
- Testing
- Trans Sodium Crocetinate, Normal saline
- Where
- Romania
- Volunteers
- 25 people
- Sponsor
- Diffusion Pharmaceuticals Inc
Olfactory Disorder, Olfaction Disorders
Intranasal Injection of PRP Versus Saline for Treatment of Olfactory Dysfunction
This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PrP) in the treatment of olfactory dysfunction.
- Conditions
- Olfactory Disorder, Olfaction Disorders, Olfactory Nerve Injuries, Olfactory Nerve Disorder
- Trial name
- NCT04406584
- Testing
- Injection into olfactory cleft
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Long COVID, Long COVID-19
RECOVER-NEURO: Platform Protocol to Measure the Effects of Cognitive Dysfunction Interventions on Long COVID Symptoms
This platform protocol is designed to be flexible so that it is suitable for a wide range of settings within health care systems, for remote settings, and in community settings where it can be integrated into COVID-19 programs…
- Conditions
- Long COVID, Long COVID-19, Long COVID19
- Trial name
- NCT05965752
- Testing
- BrainHQ/Active Comparator Activity, BrainHQ, PASC CoRE
- Where
- 24 sites in United States
- Volunteers
- 328 people
- Sponsor
- Duke University
Covid-19
Octagam 10% Therapy in COVID-19 Patients With Severe Disease Progression
This is a randomized, double-blind, placebo-controlled, multicenter, Phase 3 study to evaluate if high-dose Octagam 10% therapy can stabilize or improve clinical status in patients with severe Coronavirus disease
- Trial name
- NCT04400058
- Testing
- Octagam 10%, Saline Solution
- Where
- 22 sites in United States, Russia and 1 more
- Volunteers
- 207 people
- Sponsor
- Octapharma
Antiphospholipid Syndrome, COVID-19 Infection
Prospective Observational Study to Evaluate a Possible Change in APS Antibody Profiles After COVID-19 Infection or Vaccination
Prospective observational study to evaluate a possible change in APS antibody profiles after COVID-19 infection or vaccination
- Conditions
- Antiphospholipid Syndrome, COVID-19 Infection, COVID-19 Vaccination
- Trial name
- APSantiCo (NCT05313048)
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Cardioangiologisches Centrum Bethanien
Corona Virus Infection
Demographics and Outcomes of COVID 19 in Pregnancy at a Community Based Hospital
Demographics of pregnant COVID persons under investigation and those who were positive from March-May 2020. Looking at demographics including age, socio-economic status and pregnancy outcomes in these groups.
- Trial name
- NCT04385914
- Testing
- COVID positive via testing
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
COVID-19, Venous Thromboembolism
Clinical Trial of Dimolegin (DD217) in Prevention of Thrombotic Complications in Patients With COVID-19
Study purpose was to study the safety and efficacy of Dimolegin - DD217 as a drug for prevention of thrombotic complications compared to Clexane (enoxaparin sodium) - the standard therapy currently prescribed to patients…
- Trial name
- NCT05185804
- Testing
- Dimolegin, Clexane
- Where
- 6 sites in Russia
- Volunteers
- 399 people
- Sponsor
- PharmaDiall Ltd.
COVID-19, Desaturation of Blood
Hyperbaric Oxygen Therapy Effect in COVID-19 RCT (HBOTCOVID19)
The 2019-20 coronavirus disease, caused by COVID-19, is an ongoing pandemic.So far, no specific treatment has proven efficacy. Recent case series reported the use of Hyperbaric Oxygen Therapy (HBOT) on 5 severe COVID-19 patients…
- Trial name
- HBOTCOVID19 (NCT04358926)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
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