Clinical trials: Infections, Coronavirus
COVID-19, Vaccine Adverse Reaction
Adverse Events Report of Inactivated COVID-19 Vaccine
Numerous vaccination studies are conducted to protect against COVID-19 infection, and preclinical and clinical studies are still ongoing worldwide.
- Trial name
- NCT05026879
- Testing
- Inactivated COVID-19 vaccine (CoronaVac)
- Where
- Turkey (Türkiye)
- Volunteers
- 4,040 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Acute Respiratory Distress Syndrome, ARDS (Moderate or Severe)
Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)
This is a multi-center, randomized, placebo controlled, interventional phase 2A trial to evaluate the safety profile and potential efficacy of multi-dosing of mesenchymal stromal cells (MSC) for patients with SARS-CoV-2…
- Conditions
- Acute Respiratory Distress Syndrome, ARDS (Moderate or Severe), COVID-19 Pneumonia
- Trial name
- NCT04466098
- Testing
- Mesenchymal stromal cells
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
CoV2 SARS Pneumonia
Predicting the Progression to Chronic Fibrosis of Lung Lesions Related to Covid-19 Infection From Chest CT Images
The main differences observed between SARSCoV-2 pneumonia and other epidemic viral pneumopathies (e.g., seasonal influenza) are the greater infectivity of SARSCoV-2, the clinical severity of the disease, particularly in young…
- Trial name
- PREDISCAN (NCT04483752)
- Testing
- CHEST CT SCAN
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Coronavirus Disease 2019
Inhaled Interferon α2b for the Treatment of Coronavirus Disease 19 (COVID-19)
The IN2COVID Study is a 2-staged phase I/II double-blind, randomized, placebo-controlled trial to evaluate the efficacy and safety of AP-003 (Interferon α2b) when administered via inhalation twice daily for 10 days.
- Trial name
- IN2COVID (NCT04988217)
- Testing
- Interferon-Alpha2B
- Where
- Chile
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
COVID-19
Decitabine for Coronavirus (COVID-19) Pneumonia- Acute Respiratory Distress Syndrome (ARDS) Treatment: DART Trial
This is a a randomized double blind placebo controlled Phase 2 trial with a 12 patient lead-in to evaluate safety, prior to full enrollment to an additional 28 patients (for a total of 40 patients) to assess efficacy of…
- Trial name
- DART (NCT04482621)
- Testing
- Decitabine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Johns Hopkins University
COVID-19, Complicated Appendicitis
Complicated Appendicitis During the COVID-19 Pandemic in Jordan
Comparing the incidence of complicated appendicitis between two groups, the pandemic and pre-pandemic groups.
- Trial name
- NCT05375058
- Testing
- Observational Study
- Where
- Jordan
- Volunteers
- 257 people
- Sponsor
- Jordan University Hospital
Long COVID
Effect of Lithium Therapy on Long COVID Symptoms
This study will assess low-dose lithium's effects on several different symptoms experienced by long COVID patients.
- Trial name
- NCT05618587
- Testing
- Lithium
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- State University of New York at Buffalo
a Randomized Double-blind Study, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
The Effectiveness of Phytotherapy in SARS-COV2(COVID-19)
Quercetin is one of the flavonoids. Quercetin as well as rutin are recognized to be among the most active of the flavonoids. It is to quercetin that several medicinal plants, including ginkgo and St.
- Conditions
- a Randomized Double-blind Study, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), PHYTOTHERAPIE
- Trial name
- Quercetix (NCT04851821)
- Testing
- Quercetin
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- Hôpital Universitaire Sahloul
Covid19, SARS-CoV Infection
Initial CT Findings and CO-RADS Stage in COVID-19
This study aims to determine whether patients with different real-time reverse transcriptase-polymerase chain reaction (PCR), chest computed tomography (CT) and laboratory findings have different clinical outcomes.
- Conditions
- Covid19, SARS-CoV Infection, Pneumonia, Viral
- Trial name
- NCT04789447
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 895 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
COVID-19
Canadian Adaptive Platform Trial of Treatments for COVID-19 in Community Settings
CanTreatCOVID is an open-label, individually randomized, multi-centre, national trial. CanTreatCOVID aims to establish an adaptive platform trial aimed at evaluating the clinical- and cost-effectiveness, practical challenges, and…
- Trial name
- CanTreatCOVID (NCT05614349)
- Testing
- Paxlovid, Antioxidant
- Where
- 6 sites in Canada
- Volunteers
- 797 people
- Sponsor
- Unity Health Toronto
COVID-19, Type 2 Diabetes Mellitus
Effects of Telerehabilitative Aerobic and Relaxation Exercises Patients With Type 2 Diabetes With and Without COVID-19
Type-2 Diabetes Mellitus (DM) disease, like other chronic diseases, is a group of diseases that are adversely affected by the COVID-19 pandemic.This study was planned to examine the effect of COVID-19 disease on patients with…
- Trial name
- NCT05411458
- Testing
- Aerobic and Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bozyaka Training and Research Hospital
Covid19, Myeloma Multiple
Impact of COVID-19 After Autologous Hematopoietic Stem Cell Transplantation in Sweden
This retrospective observational cohort study aims to describe the impact of COVID-19 in patients treated with autologous stem cell transplantation (ASCT) for malignant disease in terms of risk factors, morbidity, need for…
- Conditions
- Covid19, Myeloma Multiple, Malignant Lymphoma, Hematologic Neoplasms
- Trial name
- AutoCOVID-19 (NCT04760184)
- Testing
- Autologous stem cell transplantation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University
Coronavirus Infection
Treating COVID-19 With a Bidirectional Oxygenation Valve
This study will utilize a single center internal control study design. The objective of this study is to determine the feasibility and safety of a bidirectional oxygenation PEEP generating mouthpiece when combined with oxygen by…
- Trial name
- NCT04326452
- Testing
- bidirectional oxygenation mouthpiece
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- TMC HealthCare
Covid19
A Immuno-bridging and Immunization Schedules Study of COVID-19 Vaccine (Vero Cell), Inactivated
This trial is a randomized study to evaluate the immunogenicity of COVID-19 Vaccine (Vero Cell), Inactivated and in population aged 60 years old and 3-17 years old with different schedules compared to that in population aged…
- Trial name
- COVID-19 (NCT04863638)
- Testing
- 3-doses schedule 1 of COVID-19 Vaccine (Vero Cell), Inactivated, 3-doses schedule 2 of COVID-19 Vaccine (Vero Cell), Inactivated, 3-doses schedule 3 of COVID-19 Vaccine (Vero Cell), Inactivated
- Where
- China
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Covid19, SARS-CoV Infection
Collection of the Thrombo-VaxCov Cohort
In the context of anti-Covid19 vaccination, atypical thrombosis have occured and potential link with vaccination is under investigation.
- Conditions
- Covid19, SARS-CoV Infection, Venous Thrombosis, Thrombocytopenia
- Trial name
- THROMBO-VAXCOV (NCT04889326)
- Testing
- Retrospective data and biological samples
- Where
- France
- Sponsor
- University Hospital, Lille
COVID-19
Transfusion and COVID-19
Alsace was particularly and early on affected by SARS-CoV-2 and quickly implemented a reduction in scheduled admissions and non-urgent surgical interventions, making it possible to reduce requests for labile blood products linked…
- Trial name
- TRANSCOV-19 (NCT05075915)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Covid19
Clinical Study Spartan COVID-19 V2 System (Canada Alternate)
This multicentre prospective study will enroll a sufficient number of patients to afford approximately 30 positives and > 30 negatives (as determined by the SOC - Comparator method) in the United States and/or Canada.
- Trial name
- NCT04628208
- Testing
- Spartan COVID-19 v2 System
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Spartan Bioscience Inc.
Pneumonia, Influenza
ACTIVATE in Public Housing
This multilevel, multidisciplinary, theoretically based, culturally sensitive, community-engaged intervention sets out to mitigate uptake barriers and non-adherence to vaccination schedules as recommended by the CDC and increase…
- Conditions
- Pneumonia, Influenza, Varicella Zoster, Meningitis
- Trial name
- NCT06075732
- Testing
- Increasing Willingness and Uptake of Influenza, Pneumonia, Meningitis, HZV, and COVID-19 Vaccination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
COVID-19 Testing, CNS Disease
Determination of COVID-19 Related Virus in Central Nervous System
Coronavirus disease 2019 (COVID-19) is a highly infectious pandemic disease caused by SARS-CoV-2 virus. Central Nervous System (CNS) complications associated with COVID-19 might be secondary sequelae due to exuberant systemic…
- Conditions
- COVID-19 Testing, CNS Disease, CNS Infection
- Trial name
- NCT04775784
- Testing
- Determination of SARS-CoV2 presence in CNS
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele
Solid Carcinoma, Post Traumatic Stress Disorder
Psychological Care of Oncology Patients With Post-traumatic Stress in the Context of a COVID-19
In the context of the COVID-19 pandemic, concerns of the risk of infection may lead to fear, anxiety or psychological disorders that may become generalised and long-lasting, corresponding to post-traumatic stress disorder (PTSD).
- Conditions
- Solid Carcinoma, Post Traumatic Stress Disorder, Covid19
- Trial name
- COVIPACT 2 (NCT04747249)
- Testing
- Psychological support
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Francois Baclesse
The first 5,000 results can be paged through. Add a filter or change the sort order to reach the rest.