Clinical trials: Infections, Upper Respiratory Tract
Virus Diseases in Children
A Study to Investigate the Effect of Probiotics (Limosilactobacillus Reuteri DSM 17938 and Limosilactobacillus Reuteri DSM 33633) on Symptoms of Viral Upper Respiratory Tract Infections in Children
This study investigates the effect of Limosilactobacillus reuteri probiotic strains (DSM 17938 and DSM 33633) on symptoms of viral upper-respiratory tract infections in children.
- Trial name
- NCT07870824
- Testing
- Probiotics (L. reuteri DSM 17938 and L. reuteri DSM 33633)
- Where
- Hungary
- Volunteers
- 194 people
- Sponsor
- Milosevits Gergely
Respiratory Distress Syndrome, Lower Respiratory Tract Infection
A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits
Purpose: Using a novel oxygen blender prototype with modified bCPAP to manage children 1 month to 5 years of age hospitalized with respiratory distress due to lower respiratory tract infection (LRTI) in low-resource settings is…
- Trial name
- NCT04311320
- Testing
- Low-Resource Oxygen Blender
- Where
- Cambodia
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Acute Rhinosinusitis, Allergic Rhinitis
An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms
This is a study to learn more about the common cold from studying the nasal secretions produced during a cold or episode of allergic rhinitis.
- Trial name
- NCT01553110
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Virginia Commonwealth University
Upper Respiratory Tract Infections
Vitamin D Supplementation and Upper Respiratory Tract Infections in Adolescent Swimmers
Background: The medical and economic burden of upper respiratory tract infections (URTIs) is extremely high, while prevention and treatment options are limited.
- Trial name
- NCT01215682
- Testing
- vitamin D
- Where
- 4 sites in Israel
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Exercise Induced Asthma, Exercise Induced Pharyngeal Collapse
Diagnostics and Quality of Life With EIA and EILO
The purpose of this study is to investigate the quality of life of subjects suffering from dyspnoea while exercising and quantify the number of diagnoses of Exercise induced Asthma (EIA) and Exercise induced laryngeal obstruction…
- Trial name
- NCT03550456
- Testing
- ECC, ECC with CLE, Speech therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Respiratory Tract Infections (RTI), Lower Respiratory Tract Infection (LRTI)
Respiratory Infections in Young Children
The goal of this observational study is to learn about the causes, severity, and long-term effects of respiratory tract infections (RTIs) in young children from birth to five years of age in Colombia and Panamá.
- Conditions
- Respiratory Tract Infections (RTI), Lower Respiratory Tract Infection (LRTI), Viral Infections, Cohort Study
- Trial name
- MINERVAL (NCT07249996)
- Where
- 2 sites in Colombia, Panama
- Volunteers
- 1,088 people, healthy volunteers welcome
- Sponsor
- Eduardo Lopez -Medina
Lower Respiratory Tract Infection, Community Acquired Pneumonia
The Effect of Focused Lung Ultrasonography on Antibiotic Prescribing in General Practice
The goal of this randomised controlled trial is to determine if adults presenting with symptoms of an acute lower respiratory tract infection in general practice where the general practitioner suspects CAP, who have FLUS…
- Trial name
- PLUS-FLUS (NCT06210282)
- Testing
- Focused lung ultrasound (FLUS), Usual Care
- Where
- Denmark
- Volunteers
- 391 people
- Sponsor
- Aalborg University
Upper Respiratory Tract Infections, Urinary Tract Infections
Routine Prescription Feedback and Peer Comparison to Lower Antibiotic Prescriptions in Primary Care
To evaluate the effect of a continuous postal and web-based feedback and peer comparison system of individual antibiotic prescription rates on the prescription behaviour of primary care physicians in Switzerland.
- Trial name
- NCT01773824
- Testing
- Antibiotic prescription feedback, No Feedback
- Where
- Switzerland
- Volunteers
- 2,900 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Upper Respiratory Tract Infection, Influenza
Kagocel® for the Prevention of ARVI and Influenza in Adults Health Care Workers
this study evaluates the use of Kagocel for the prevention of acute respiratory viral infections (ARVI) and influenza during the epidemic rise in morbidity in Russia in the 2017-2018 season (epidemiology: number of cases during…
- Conditions
- Acute Upper Respiratory Tract Infection, Influenza, Respiratory Viral Infection
- Trial name
- NCT04611061
- Testing
- Kagocel, No one
- Where
- Russia
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Nearmedic Plus LLC
Respiratory Tract Infections
A Study of Rilematovir in Infants and Children and Subsequently in Neonates Hospitalized With Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus (RSV)
The purpose of the study is to evaluate the efficacy of rilematovir compared to placebo treatment with respect to the clinical outcome on the RSV Recovery Scale (RRS).
- Trial name
- DAISY (NCT04583280)
- Testing
- Rilematovir, Rilematovir X mg/kg
- Where
- 142 sites in United States, Argentina and 24 more
- Volunteers
- 28 people
- Sponsor
- Janssen Research & Development, LLC
Sore Throat
The Effect of Cold Vapor Application on Postoperative Sore Throat
To determine the effect of cold vapor given in the post-extubation period on sore throat.
- Trial name
- NCT05317520
- Testing
- Cold vapor
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
COVID-19 Pneumonia, COVID-19
Immuno-bridging Study of Inactivated SARS-CoV-2 Vaccine in Healthy Population Aged 3-17 vs Aged 18 Years Old and Above
This is a open label clinical trial to evaluate the efficacy, safety and immunogenicity of inactivated SARS-CoV-2 vaccines (Vero cell) in healthy people aged 3-17 years old in comparison with healthy population aged 18 years old…
- Trial name
- COVID-19 (NCT04917523)
- Testing
- SARS-CoV-2 Vaccine (Vero Cell), Inactivated
- Where
- United Arab Emirates
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Fever, Respiratory Tract Infections
Diagnostic Accuracy of a Host-response Based Diagnostic Tool for Distinguishing Between Bacterial and Viral Etiologies in Pediatric Patients
This is a prospective clinical validation study of a novel regulatory approved (CE-IVD) diagnostic assay called ImmunoXpert™ that will enroll 1222 pediatric patients.
- Trial name
- AutoPilot (NCT03052088)
- Where
- 2 sites in Germany, Italy
- Volunteers
- 1,140 people
- Sponsor
- MeMed Diagnostics Ltd.
Cardiovascular Disease
A Study Exploring the Effect of Adjuvanted RZV or RSVPreF3 Vaccines on Coronary Plaque Progression in Adults >=50 Years of Age at Risk for Cardiovascular Events
This study is designed to evaluate whether the adjuvanted recombinant zoster vaccine (RZV) or the adjuvanted respiratory syncytial virus PreFusion protein 3 (RSVPreF3) vaccine can attenuate the progression of coronary plaque in…
- Trial name
- NCT07712380
- Testing
- Adjuvanted RZV vaccine, Adjuvanted RSVPreF3 vaccine
- Volunteers
- 450 people
- Sponsor
- GlaxoSmithKline
Viral Gastro Enteritis, Pharyngitis
Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption
In France, patients with benign viral infections (ie: gastro enteritis and/or rhinopharyngitis, etc.) often receive several prescriptions from their doctors, although there is evidence that these medicines are not efficient.
- Trial name
- NCT02237573
- Testing
- Written medical report and standardized medical advices, Control
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Paris 7 - Denis Diderot
COVID-19
Immunogenicity and Safety of a Third Dose of COVID-19 Vaccine(Vero Cell), Inactivated in the Elderly
This is an open phase Ⅲ clinical trial of COVID-19 vaccine (Vero cell), inactivated manufactured by Sinovac Research \& Development Co., Ltd.The purpose of this study is to evaluate Immunogenicity and safety of a third dose at…
- Trial name
- NCT05398926
- Testing
- COVID-19 Vaccine (Vero cell), Inactivated
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.