Clinical trials: Infectious Disease of Abdomen
Gut Microbiota, Intra-abdominal Infections
Gut Microbiota Analysis in IAI Patients With Sepsis-associated Liver Dysfunction
With the rapid development of intensive care medicine, the mortality of patients with sepsis has decreased over the past decade, but it is still the leading cause of death in intensive care unit (ICU).
- Conditions
- Gut Microbiota, Intra-abdominal Infections, Acute Gastrointestinal Injury, Sepsis-associated Liver Dysfunction
- Trial name
- 2022-11-09 (NCT05628493)
- Testing
- Gut microbiota Analysis
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese Medical Association
Peritoneal Dialysis Catheter Infection
Reduction of Exit Site Infection in Peritoneal Dialysis Patients
In peritoneal dialysis patients, the presence of the catheter presents a risk of infection - exit site infection, tunnel infection or peritonitis.
- Trial name
- NCT03798171
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Appendicitis
The Safety and Pharmacokinetics of Intraperitoneal Administration in Patients Undergoing Appendectomy for Uncomplicated Appendicitis
The objective of this trial is to evaluate the safety of the intraperitoneal administration of the combination of fosfomycin, metronidazole, and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients undergoing…
- Trial name
- NCT03046758
- Testing
- A combination of fosfomycin, metronidazole and GM-CSF i.p.
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Herlev Hospital
Intraabdominal Infections
A Study of Levornidazole Disodium Phosphate for Injection vs. Ornidazole in Treatment of Postoperative Intra-Abdominal Infections Caused by Anaerobic Bacteria
Anaerobic infections are very common in clinical practice. Poor control of anaerobic infections in patients undergoing abdominal surgery may lead to the occurrence of complications.
- Trial name
- NCT06828874
- Testing
- Levornidazole Disodium Phosphate for Injection, Ornidazole and Sodium Chloride Injection
- Where
- 32 sites in China
- Volunteers
- 696 people
- Sponsor
- Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Acute Appendicitis
Laparoscopic Assisted or Total Laparoscopic Appendectomy
Acute appendicitis (AA), is a common intra-abdominal surgical pathology with the overall incidence of approximately 7% and mortality of 0.2-0.8%.
- Trial name
- NCT02673528
- Testing
- Laparoscopic appendectomy
- Volunteers
- 451 people
- Sponsor
- Medical Park Gaziantep Hospital
Low Gelsolin, Trauma
Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels
This study is designed to assess the pharmacokinetics and safety of an infusion of a single dose of recombinant plasma gelsolin (rhu-pGelsolin) when given to patients admitted to the Intensive Care Unit with documented low levels…
- Conditions
- Low Gelsolin, Trauma, Infection, Burns
- Trial name
- NCT00671307
- Testing
- rhu-pGelsolin
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Critical Biologics Corporation
Acute Appendicitis, Superficial SSI
Laparoscopic vs Open Appendectomy
his randomized controlled trial was conducted to compare the frequency of superficial surgical site infections (SSIs) following laparoscopic appendectomy and open appendectomy in patients undergoing surgical treatment for acute…
- Trial name
- NCT07841444
- Testing
- Laparoscopic appendectomy, Open Appendectomy
- Where
- Pakistan
- Volunteers
- 276 people
- Sponsor
- Quaid-e-Azam Medical College
Intra-Abdominal Infections, Skin Disease, Infectious
Tygacil Drug Use Investigation
Secondary Data Collection Study; safety and effectiveness of Tigecycline .under Japanese medical practice
- Trial name
- TIGER (NCT01789905)
- Testing
- Tigecycline (Tygacil)
- Volunteers
- 116 people
- Sponsor
- Pfizer
Acute Appendicitis
Endoscopic Retrograde Appendicitis Therapy
This is a prospective pilot study on the efficacy of endoscopic therapy for adult uncomplicated acute appendicitis. In recent years, antibiotics treatment has been a new alternative approach to surgical appendicectomy for acute…
- Trial name
- NCT04281251
- Testing
- Endoscopic retrograde appendicitis therapy
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Pneumonia, Necrotizing Soft Tissue Infection
The Role of Circadian Clock Proteins in Innate and Adaptive Immunity
Our data suggest that modulating the characteristics of light carries the potential to modify the host response to injury and critical illness and thus, improve outcome.
- Conditions
- Pneumonia, Necrotizing Soft Tissue Infection, Intraabdominal Infections, Infection Joint
- Trial name
- NCT03482245
- Testing
- Blue Light
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Washington University School of Medicine
Peritoneal Infection
Intervention to Reduce Infectious Complications of Peritoneal Dialysis
Peritonitis is a common and serious complication of peritoneal dialysis (PD) and is one of the main causes of peritoneal dialysis technique failure and long-term hemodialysis conversion.
- Trial name
- NCT06536673
- Testing
- Intervention to reduce infectious complications of peritoneal dialysis, Data collection from the patient's clinical history
- Volunteers
- 80 people
- Sponsor
- Universitat de Lleida
Septic Peritonitis
Effects of Dexmedetomidine vs Propofol in Patients With Intra-abdominal Sepsis
Sepsis is defined as systemic response to infection ,and it is a main problem in ICU and despite advance in supportive care, the mortality rate in patients with severe sepsis continues to exceed 30% [Bone RC 1993].The effects of…
- Trial name
- NCT04718714
- Testing
- Midazolam, Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Appendicitis, Laparoscopic
Solo and Non-solo Approach for Laparoscopic Appendectomy (SOLOAP)
To determine the safety and feasibility of solo laparoscopic appendectomy, which is defined as the application of solo surgery to laparoscopic appendectomy, by comparing consecutive non-solo procedures conducted by a surgeon in…
- Trial name
- NCT03224364
- Testing
- nonsolo LA, solo LA
- Volunteers
- 150 people
- Sponsor
- Say-June Kim
Acute Appendicitis
Perioperative Hyperoxygenation and Wound Site Infection Following Surgery for Acute Appendicitis
Patients undergoing open appendectomy for acute appendicitis were enrolled in a randomized prospective study.
- Trial name
- NCT01002365
- Testing
- Oxygen delivery, Oxygen administration
- Where
- Israel
- Sponsor
- Western Galilee Hospital-Nahariya
Abdominal Sepsis, Acute Respiratory Failure
Evaluation of Regional Ventilation Distribution in Patients Affected by Abdominal Sepsis After Emergent Laparotomy
The goal of this clinical trial is to evaluate regional ventilation distribution in patients admitted to the intensive care unit after emergent laparotomy due to abdominal sepsis.
- Conditions
- Abdominal Sepsis, Acute Respiratory Failure, Ventilation Therapy; Complications, Emergencies
- Trial name
- CHESTOMY (NCT05726500)
- Testing
- Arterial blood gas analysis, Venous blood gas analysis, Esophageal pressure monitoring
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Università degli Studi di Ferrara
Valid MeSH Conditions
Textbook Outcomes in Urgent Appendectomy
A "textbook outcome" patient is defined as one whose surgical course is uneventful, with no complications, readmissions, or mortality.
- Trial name
- APPX_TEXTBOOK (NCT06765044)
- Volunteers
- 500 people
- Sponsor
- Hospital del Mar
Appendicitis
Appendicitis With Medical Treatment
prospective study to collect data of patients with appendicitis, not receiving operation
- Trial name
- NCT00172822
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Appendicitis
Wound Infection Alexis Wound Retractor
The purpose of this study is to determine whether the incidence of surgical site wound infection will be reduced in open appendectomy patients through the use of the Alexis® wound retractor.
- Trial name
- NCT00323453
- Testing
- Open appendectomy using Alexis Wound Retractor followed by standardized wound closure, Open appendectomy with standardized wound closure
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Santa Barbara Cottage Hospital
Acute Appendicitis
Cost-effectiveness Analysis and Case-based Payment Norm Modeling on Appendicitis Patients at Hanoi Medical University Hospital
In the world, there are several studies comparing the cost-effectiveness between laparoscopic appendectomy and open appendectomy.
- Trial name
- NCT03504878
- Testing
- Laparoscopic appendectomy, Open appendectomy
- Where
- Vietnam
- Sponsor
- Hanoi Medical University