Clinical trials: Infectious Gastroenteritis
Ulcerative Colitis, Diet Habit
Micronutrient and Additive Modifications May Optimize Diet To Health
This is a prospective clinical intervention trial where patients with moderately active ulcerative colitis are randomized to either normal healthy diet or a diet with elimination of emulsifying agents within the E 400-group with…
- Conditions
- Ulcerative Colitis, Diet Habit, Microbial Colonization
- Trial name
- Mammoth (NCT05743374)
- Testing
- Normal diet, E400 elimination
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Region Skane
Gastric Atrophy, Gastric Cancer
Epidemiology of Helicobacter Pylori Infection in Moscow
H. pylori is transmitted from individual to individual and causes chronic active gastritis in all infected people. H. pylori infection can result in gastroduodenal ulcers, atrophic gastritis (AG), gastric carcinoma, and gastric…
- Conditions
- Gastric Atrophy, Gastric Cancer, Helicobacter Pylori Infection
- Trial name
- NCT05775120
- Testing
- OLGA and H.pylori culture
- Where
- Russia
- Volunteers
- 5,121 people, healthy volunteers welcome
- Sponsor
- Moscow Clinical Scientific Center
Diarrhea Infectious, Cholera
Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)
The findings from previous recent randomized controlled trials of The Cholera Hospital Based Intervention for 7 Days (CHoBI7) demonstrated that this intervention was effective in significantly reducing symptomatic cholera…
- Trial name
- CHoBI7 (NCT06498817)
- Testing
- Standard Recommendation, CHoBI7 Scale-Up Program
- Where
- Bangladesh
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Infectious Diseases
Prevention of Necrotizing Enterocolitis of Premature Newborns Under Less Than 1500 g Using Probiotics
The purpose of this study is to evaluate the incidence of necrotizing enterocolitis and its effect over the secreting immunoglobulin A in the feces with the use of probiotics of the strain Lactobacillus acidophilus boucardii vs.
- Trial name
- (PEPP) (NCT02245815)
- Testing
- use probiotics boucardii, use probiotics Multi-species
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Cholera, Water-Related Diseases
Preventative Intervention for Cholera for 7 Days
The first objective of our study is to develop a theory-driven evidence-based targeted water, sanitation, and hygiene (WASH) intervention for household members of diarrhea patients in South Kivu, Democratic Republic of the Congo…
- Conditions
- Cholera, Water-Related Diseases, Diarrhea Infectious
- Trial name
- PICHA-7 (NCT05166850)
- Testing
- PICHA7 mHealth program, Standard Arm
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 2,900 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Microbial Colonization, Peri-Implantitis
Microbiome Modulation by PEMF on Plaque Induced Mucositis in Human Jaws
To evaluate the impact of Pulsed Electromagnetic Field (PEMF) on mucositis induced in humans around dental implants and correlate these possible effects with the proteomic profile of implants with and without PEMF and teeth.
- Trial name
- NCT07045636
- Testing
- Teeth wih gingivits
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jamil awad shibli
Dysentery Amebic
Immunochromatography Versus Microscopy for Diagnosis of Entamoeba Histolytica/Dispar Infection.
Amoebiasis, an infection by the protozoan parasite Entamoeba histolytica is globally considered as the third leading parasitic cause of human mortality besides malaria and schistosomiasis. It is estimated that E.
- Trial name
- NCT04759937
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
COVID, Influenza
Innovative Tool to Limit Spread of COVID 19 in Residential Aged Care Facilities
This project is a randomised trial in order to determine if "gamification" can result in behaviour change for healthcare workers in the residential aged care setting.
- Conditions
- COVID, Influenza, Gastroenteritis
- Trial name
- NCT04377165
- Testing
- Gamification, Newsfeed function
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
LRTI, UTI
Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections
This is an observational prospective study of an in-vitro diagnostic (IVD) assay planned to enroll 632 subjects. The study will be conducted in two stages: Stage A is aimed at identifying individual biomarkers and constructing a…
- Conditions
- LRTI, UTI, Gastroenteritis, Systemic Infections/Bacteremia/Meningitis
- Trial name
- CURIOSITY (NCT01917461)
- Where
- 2 sites in Israel
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Diarrhea
Oral Rehydration Solution With Zinc and Prebiotics in Acute Diarrhea
Hypotonic oral rehydration solutions (ORS) containing zinc and/or prebiotics have been proposed for the treatment of pediatric acute diarrhea but conclusive clinical data about their effect are scanty, especially for children…
- Trial name
- NCT01025583
- Testing
- hypotonic oral rehydration solution, Hypotonic oral rehydration solution with Zn and prebiotics
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Federico II University
Gastritis, Atrophic, Helicobacter Pylori Infection
Diagnosis of Gastritis, H. Pylori Infection and Atrophic Gastritis in Dyspeptic Patients
Gastric cancer is the third most common cause of cancer-related death worldwide (1). Upper endoscopy is necessary to detect neoplastic macroscopic features at an early stage, but subtle abnormalities in the gastric mucosa are…
- Conditions
- Gastritis, Atrophic, Helicobacter Pylori Infection, Intestinal Metaplasia, Gastritis
- Trial name
- NCT04296513
- Testing
- High-Definition white light endoscopy., High-definition magnification with digital chromoendoscopy.
- Where
- Ecuador
- Volunteers
- 150 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Meningitis, Meningococcal, Rotavirus Infections
RotaTeq® and Meningococcus C Vaccine in Healthy Infants (V260-016)
Primary objective: To check if RotaTeq® can be administered concomitantly with meningococcal Group C vaccine without impairing the efficacy of MCC vaccine.
- Trial name
- NCT00443846
- Testing
- RotaTeq®, NeisVac-C®
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Gastritis, H Pylori Infection
Helicobacter Pylori Eradication With Clostridum Butyricum Capsule and Bacillus Coagulans Tablets
This study aims at evaluating efficacy Clostridum Butyricum Capsule and Bacillus Coagulans Tablets in H. pylori eradication. It is hypothesized that Clostridum Butyricum Capsule , Bacillus Coagulans Tablets monotherapy or…
- Conditions
- Gastritis, H Pylori Infection, Dyspepsia
- Trial name
- NCT03857425
- Testing
- Clostridum Butyricum Capsule, Bacillus Coagulans Tablets, Clostridum Butyricum Capsule plus Bacillus Coagulans Tablets
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Appendicitis, Cholecystitis
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)
This is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment.
- Conditions
- Appendicitis, Cholecystitis, Diverticulitis, Intra-Abdominal Abscess
- Trial name
- NCT00230971
- Testing
- tigecycline, ceftriaxone plus metronidazole
- Where
- 68 sites in Australia, China and 17 more
- Volunteers
- 473 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Ulcerative Colitis, Cytomegalovirus Infections
Prevalence of Cytomegalovirus Infection in Patients With Quiescent Ulcerative Colitis
Colitis from reactivation of established cytomegalovirus (CMV) colonization can complicate the clinical course in patients with an acute flare of ulcerative colitis (UC).
- Trial name
- PROVE-UC (NCT02684734)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Acute Appendicitis, Surgical Site Infection
Are Double-ring Wound-edge Protectors Effective for Preventing Superficial Surgical Site Infection After Open Appendectomy?
This study aims to evaluate the utility of double-ring wound-edge protectors to prevent the development of superficial surgical site infections after open appendectomy.
- Trial name
- sSSI-2RWEPs (NCT04860570)
- Testing
- Double-ring wound-edge protector
- Where
- Spain
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- Hospital Medina del Campo
Ulcerative Colitis
Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative Colitis
Ulcerative Colitis (UC) is a chronic Inflammatory Bowel Disease characterized by chronic inflammation of the colon. Composition of gut microbiota of UC patients is abnormal (dysbiosis).
- Trial name
- ABRICO (NCT06228352)
- Testing
- Feces collection
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Appendicitis
A Randomized Controlled Trial on Wound Irrigation in Open Appendectomy.
A large retrospective study compared wound irrigation with antiseptic solution, with antimicrobial agent, and with normal saline in patients undergoing open appendectomy and concluded an evident superiority of antibiotic wound…
- Trial name
- NCT04332809
- Testing
- saline-gentamicin irrigation, saline irrigation
- Where
- Egypt
- Volunteers
- 208 people
- Sponsor
- Mansoura University
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University
Osteomyelitis, Pneumonia
Comparative Effectiveness of Intravenous v. Oral Antibiotic Therapy for Serious Bacterial Infections
Some children get serious bacterial infections that require hospitalization and then a long course of antibiotics to completely treat the infection.
- Conditions
- Osteomyelitis, Pneumonia, Appendicitis
- Trial name
- PIVVOT (NCT02311452)
- Testing
- Peripherally Inserted Central Catheter (PICC)
- Volunteers
- 15,000 people
- Sponsor
- Children's Hospital of Philadelphia