Clinical trials: Infectious Keratitis
Infectious Keratitis
Non-invasive Diagnostics of Microbial Keratitis
Infectious keratitis is a significant cause of partial vision loss and blindness and places a large burden on eye care professionals.
- Trial name
- NCT06364878
- Testing
- In vivo confocal microscopy, Tear film sampling
- Where
- Norway
- Volunteers
- 125 people
- Sponsor
- Sorlandet Hospital HF
Bacterial Keratitis, Fungal Keratitis
Safety and Efficacity of Corneal Collagen Crosslinking in Infectious Keratitis (Bacterial and Fungal ): Randomized,Controlled, Prospective Study. (CXL)
The corneal collagen cross linking is currently used in the treatment of keratoconus but this procedure has also a sterilizing non-specific effect on bacteria and fungus.
- Trial name
- CXL (NCT02088970)
- Testing
- Crosslinking, antibiotic treatment
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Nantes University Hospital
Infectious Keratitis
Microbiological Diagnosis of Infectious Keratitis to Pathogenic Fastidious Germs
Infectious keratitis are favored by the circumstances causing the small trauma of the corneal epithelium, corneal surgery, corneal dryness under health system such as Sjögren's syndrome rheumatoid arthritis, or much more…
- Trial name
- Keratite (NCT02819232)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 442 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Keratitis, Myopia
Safety of Overnight Corneal Reshaping Lenses
This retrospective chart review study compares the incidence of corneal inflammation due to infection in children vs. adult patients wearing overnight corneal reshaping lenses.
- Trial name
- NCT01272271
- Volunteers
- 1,317 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Keratitis; Infectious Disease (Manifestation)
Pseudomonal Type Three Secretion System and Contact Lens Associated Microbial Keratitis
Microbial infection of the cornea, also known as microbial keratitis, causes severe corneal inflammation that could result in permanent visual loss.
- Trial name
- NCT01925846
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Limbal Stem Cell Deficiency
Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft
The main aim of the study is to determine the safety and feasibility of a cultivated autologous limbal epithelial cell (CALEC) transplantation in the treatment of limbal stem cell deficiency.
- Trial name
- CALEC (NCT02592330)
- Testing
- Biopsy to collect limbal epithelial stem cells that will be cultivated into a graft, Cultivation of Limbal epithelial cells into a graft, CALEC Transplant
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Dry Eye Syndrome, Infectious Keratoconjunctivitis
Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface
This study aims to obtain the lacrimal fingerprint for frequent pathologies of the ocular surface and establish a normative base for each of them.
- Conditions
- Dry Eye Syndrome, Infectious Keratoconjunctivitis, Mucous Membrane Pemphigoid, Allergic Conjunctivitis
- Trial name
- EML-MSO (NCT04198740)
- Testing
- Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry
- Where
- 2 sites in Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Infectious Keratitis
Crosslinking in Infectious Keratitis
Microbial keratitis is an infection of the cornea that is associated with risk of permanent visual impairment. It can be caused by bacteria, virus, fungus, protozoa and parasites.
- Trial name
- NCT03801590
- Testing
- Crosslinking with Riboflavin and UV-A
- Volunteers
- 20 people
- Sponsor
- Assiut University
Infectious Keratitis
Cross-linking as Treatment in Infectious Keratitis
To compare between SCXL and ACXL for treatment of infectious keratitis
- Trial name
- NCT04383431
- Testing
- PACK-CXL
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Sohag University