Clinical trials: Infectious Mononucleosis
PTLD, Lymphoid Tumor
A Risk Stratified Sequential Treatment With Rituximab, Brentuximab Vedotin and Bendamustine (RBvB)
This is an open label, risk-stratified, sequential treatment, phase 2 study of newly diagnosed post-transplant lymphoproliferative disorders with positive CD20 and CD30 expression.
- Conditions
- PTLD, Lymphoid Tumor, Hematopoietic/Lymphoid Cancer, Plasmacytic Hyperplasia PTLD
- Trial name
- NCT04138875
- Testing
- Rituximab, Brentuximab Vedotin, Bendamustine
- Where
- 2 sites in United States
- Sponsor
- Yale University
Epstein-Barr Virus (EBV) Infection
Occurrence of Antibodies Cross-reacting With Autoantigens in Primary EBV Infection
The aim of this study is to assess the occurrence of antibodies cross-reacting with autoantigens that have been detected in the context of SLE in patients with primary EBV infection over time compared to a control group.
- Trial name
- NCT05127980
- Testing
- Data collection: Participant characteristics (Illness course, complications of primary EBV infection and provided treatments), Data collection: blood samples (analysed for EBV serology, auto-antibody-testing/biobanking, RNA expression analyses, procalcitonin), Data collection: Patient reported outcome (Fatigue questionnaires)
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University Hospital, Basel, Switzerland
EBV, Epstein-Barr Virus Infection
Safety and Immunogenicity of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine in Healthy Adults
Background: Epstein-Barr virus (EBV) causes most cases of infectious mononucleosis (mono). Up to 1 in 10 people who get mono can have fatigue that lasts more than 6 months. One out of 100 people can have severe complications.
- Conditions
- EBV, Epstein-Barr Virus Infection, Infectious Mononucleosis
- Trial name
- NCT04645147
- Testing
- EBV gp350-Ferritin Vaccine
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Primary Health Care
HIV Indicator Diseases in Hospital and Primary Care
Patients are frequently evaluated by physicians for medical work-up of HIV indicator conditions in hospital and in primary care at the general practitioner.
- Conditions
- HIV Infections, Primary Health Care, Acquired Immunodeficiency Syndrome, Sexually Transmitted Diseases, Viral
- Trial name
- #AwareHIV (NCT05225493)
- Testing
- Peer to peer feedback, HIV rapid test
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- Erasmus Medical Center
Post-transplant Lymphoproliferative Disorder, Mononucleosis
Early Detection of Epstein-Barr Virus Related Disease.
Epstein-Barr virus (EBV) is one of several herpesviruses that cause disease in humans. EBV virus has an oncogenic potential, and it has been associated with the development of a wide range of cancers.
- Conditions
- Post-transplant Lymphoproliferative Disorder, Mononucleosis, Epstein-Barr Virus Infections, Epstein-Barr Virus Related Malignancy
- Trial name
- NCT03546101
- Where
- Denmark
- Volunteers
- 1,527 people
- Sponsor
- University of Aarhus