Clinical trials: Inferior Alveolar Nerve Block
Symptomatic Irreversible Pulpitis
Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpitis
The aim of the study is to evaluate the effect of preoperative administration of acetaminophen- codeine -caffeine combination on the success of the inferior alveolar nerve block versus bacetaminophen alone or placebo in patients…
- Trial name
- NCT04202406
- Testing
- Acetaminophen and codeine and caffeine, Acetaminophen
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Cairo University
Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis
Effect of preoperative oral Ibuprofen on anesthetic efficacy of inferior alveolar nerve block with supplemental buccal and lingual infiltrations using articaine in mandibular molar teeth with irreversible pulpitis.
- Trial name
- NCT05927922
- Testing
- Oral Ibuprofen (Abbott, Egypt)
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars
The purpose of this trial is to study the ability of a frequently used dental anesthetic (articaine) to achieve complete numbness of a diseased tooth with the most commonly used injection technique in the lower jaw (inferior…
- Trial name
- ARTIC (NCT01496846)
- Testing
- IANB Articaine, SUP Articaine, SUP Lidocaine
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Michigan
Tooth Extraction
Infiltration Anesthesia vs. Block Anesthesia
Checking the effectiveness of the infiltration technique of local anesthetic agent as an alternative to inferior dental nerve block during tooth extraction
- Trial name
- LAI (NCT06766981)
- Testing
- Infiltration with Articain 4%, Inferior Alveolar Nerve Block
- Where
- 2 sites in Iraq
- Volunteers
- 100 people
- Sponsor
- Sinan A. Shwailiya
Tooth Extraction, Dental Anesthesia
Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?
This study is a Randomized Controlled Trial (RCT) which objective is to compare the effectiveness, efficacy and complication associated to an infiltrative anesthetic technique for the removal of lower third molars comparing it to…
- Trial name
- NCT03443726
- Testing
- Nerve block technique, Infiltrative technique, 4% articaine 1:100.000 epinephrine
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Anesthesia; Reaction, Pain
Anesthetic Efficacy of Gow-Gates Versus Conventional Inferior Alveolar Nerve Block Techniques
The purpose of this study is to determine whether Gow Gates block injection is more effective than conventional alveolar nerve block in anesthetising mandibular molars with acute pulpitis.
- Trial name
- NCT01329874
- Testing
- Type of block injection
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Irreversible Pulpitis
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis
This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with…
- Trial name
- NCT04157036
- Testing
- Ibuprofen, Methylprednisolone
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Pain
Efficiency Evaluation of Intradiploic Intra-osseus Anesthesia Versus Inferior Alveolar Nerve Block
Management of dental pain emergencies is a challenge for the clinician, particularly when pain is due to endodontic infection. Tested hypothesis is intradiploic anesthesia is more effective and quicker than inferior alveolar…
- Trial name
- NCT01177423
- Testing
- Dental anesthesia
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Anesthesia
Comparison of Articaine Mandibular Infiltration to Lidocaine Inferior Alveolar Nerve Block in Pediatric Patients
This is a prospective, single-blind, parallel-design randomized controlled clinical trial that aims compare the effectiveness of articaine local infiltration to lidocaine inferior alveolar nerve block (IANB) for restorative…
- Trial name
- NCT04865848
- Testing
- Dental local anesthesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Irreversible Pulpitis, Failed Inferior Alveolar Nerve Block
Articaine Versus Lidocaine for Supplemental Buccal Infiltration in Lower First Molars With Irreversible Pulpitis
Local anesthetic is used to numb a tooth before a root canal treatment. In lower back teeth with irreversible pulpitis (a painful, inflamed tooth nerve), the standard numbing injection near the jaw nerve, called an inferior…
- Trial name
- ARTLID-IP (NCT07869394)
- Testing
- Articaine 4% with epinephrine 1:100,000, Lidocaine 2% with Epinephrine 1:100,000
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Rehman Medical Institute - RMI
Local Anesthetic Complication
Buccal Infiltration Technique Compared to Inferior Alveolar Technique
This study was conducted to compare the efficacy of the buccal infiltration technique with inferior alveolar nerve block technique for alleviation of intraoperative pain during pulpal treatment of second mandibular primary molars…
- Trial name
- NCT04812639
- Testing
- Buccal infiltration technique, Inferior alveolar nerve block technique
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandibular Nerve, Mandibular Nerve Blocks
Comparative Assessment of Mental/Incisive and Inferior Alveolar Nerve Block Anesthesia in Root Canal Treatment of Mandibular Premolars
The goal of this clinical trial is to systematically compare the pain scores and anesthesia efficacy of IANB and MNB in the treatment of symptomatic mandibular first and second premolars.
- Conditions
- Mandibular Nerve, Mandibular Nerve Blocks, Premolars, Mental Nerve Block
- Trial name
- NCT06679660
- Testing
- inferior alveolar nerve block with 4% articaine, Mental/Incisive Nerve Block (%4 Articaine)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Pain Perception, Local Anesthesia
Pain Perception Comparison of Computerized vs Conventional Injection Methods
This study was conducted to a Comparison of Pain Perception for Nerve Block and Infiltration Injection Using the Conventional Method and Two Computerized Control Systems.
- Trial name
- NCT06129162
- Testing
- Conventional Syringe, STA Single Tooth Anesthesia® System., Star Pen anesthesia device.
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Extraction, Tooth Extraction Site Healing
Comparison of Intraligamentary Anesthesia With the Inferior Alveolar Nerve Block for the Extraction of Mandibular Molars.
Local anaesthesia or numbing is done before tooth extraction. This study compares two different methods of numbing molar teeth before extraction.
- Trial name
- NCT06611865
- Testing
- Intraligamentary anaesthesia, Inferior alveolar nerve block
- Where
- Pakistan
- Volunteers
- 535 people
- Sponsor
- Hamza Zia Ahmed
Drug Effect, Pulpitis - Irreversible
Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis
This is a randomized controlled trial comparing the anaesthetic efficacy of 1.8 and 3.6 mL of Articaine for inferior alveolar nerve block when treating mandibular molars with Irreversible Pulpitis
- Trial name
- IANB (NCT05840913)
- Testing
- Articaine HCl 4 % / EPINEPHrine 1:100,000 in 1.8 mL Dental Cartridge
- Where
- 2 sites in Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Procedural Pain
A Combined 2% Lidocaine Anesthetic Technique for Mandibular Molar Procedures Without Inferior Alveolar Nerve Block
This prospective single-arm pilot study evaluated the clinical effectiveness of a combined local anesthetic technique using 2% lidocaine with 1:100,000 epinephrine for dental procedures involving mandibular molars.
- Trial name
- NCT07771452
- Testing
- Lidocaine 2% with 1:100 000 epinephrine
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Herat University
Irreversible Pulpitis
Effect of Addition of Mannitol to Bupivacaine on IANB Success and Post-endodontic Pain
Inferior alveolar nerve block using either 0.5% bupivacaine alone or in addittion to mannitol in patients with irreversible pulpitis in mandibular molars.
- Trial name
- NCT03749408
- Testing
- bupivacaine plus mannitol, bupivacaine alone
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pain, Procedural
Two Approaches in Enhancing the Efficacy of Inferior Alveolar Nerve Block During Treatment of Mandibular First Permanent Molars With Symptomatic Irreversible Pulpitis
The study is designed as a randomized parallel controlled trial with three groups. Participants aged above 18 years with the first permanent molars with symptomatic signs of irreversible pulpitis will be randomly assigned into 3…
- Trial name
- NCT05427903
- Testing
- Cryotherapy, Buccal local anesthetic infiltration using articaine 4% 1:100000 epinephrine
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Failed Mechanical Induction
Efficacy of Two Injection Techniques on Success Rate of Inferior Alveolar Nerve Anesthesia
Forty healthy patients with including criteria who failed to infra alveolar nerve block injection (without lip numbness) have been randomly divided into two groups on a random basis and have received Gow-Gates or another inferior…
- Trial name
- NCT02543619
- Testing
- Injection technique
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences