Clinical trials: Infertile Patients
Fertility Issues, Breast Cancer
Effects of Naturalistic Decision-Making Model-based Oncofertility Care Education
his study examined the effects of an oncofertility education program on decisional conflict in nurses caring for breast cancer patients and patients with breast cancer. Other predictors of decisional conflict were also examined.
- Conditions
- Fertility Issues, Breast Cancer, Education
- Trial name
- NCT04600869
- Testing
- Naturalistic Decision-Making Model-based Oncofertility Care Education
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Unexplained Infertility
The Effect of LMWH on ICSI in Patients With Unexplained Infertility and Negative Immunological Markers
The purpose of this study is to assess the efficacy of LMWH treatment in women with unexplained infertility and negative immunological markers undergoing ICSI.
- Trial name
- NCT02861105
- Testing
- LMWH, 0.9% saline solution
- Volunteers
- 716 people
- Sponsor
- Ain Shams University
Thyroiditis, Autoimmune, Infertility
Effect of Prednisone and Aspirin on IVF-ET Outcome Among Patients With Thyroid Autoimmunity
This trial was a 1:1 (active:placebo) randomized, double-blind, placebo-controlled trial to evaluate the safety and efficacy of prednisone and aspirin for the in vitro fertilization and embryo transfer outcome among patients with…
- Trial name
- NCT05578456
- Testing
- Prednisone and Aspirin
- Volunteers
- 540 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Non-obstructive Azoospermia
Intra-Testicular Transplantation of Autologous Stem Cells for Treatment of Non-Obstructive Azoospermia Male Infertility.
This is an open label, single arm, single center investigation to assess the safety and efficacy of purified adult autologous, bone marrow derived, highly specialized, differentiation specific into spermatogonial lineages, and…
- Trial name
- NCT02641769
- Testing
- Stem Cell Transplantation
- Where
- Jordan
- Volunteers
- 600 people
- Sponsor
- Stem Cells Arabia
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
Estradiol 8 vs 12 mg for Endometrial Preparation in HRT-FET
The goal of this clinical trial is to learn whether 12 mg or 8 mg of oral estradiol valerate is better for preparing the endometrium in women undergoing hormone replacement frozen embryo transfer (HRT-FET) cycles.
- Conditions
- Infertility (IVF Patients), Infertility Assisted Reproductive Technology, Frozen Embryo Transfer (FET), Endometrial Preparation
- Trial name
- NCT07526207
- Testing
- Progynova®
- Where
- 2 sites in Egypt
- Volunteers
- 850 people
- Sponsor
- Cairo University
Infertility
Effect of Recombinant Follicular Stimulating Hormone (FSH) Dosing Following Cori-follitropin Alfa
In the trial, women planned to be treated with 150μg corifollitropin alfa followed by rFSH in a fixed GnRH antagonist protocol will be asked to participate and sign the ICF.
- Trial name
- TBC (NCT03686852)
- Testing
- same medications but different dosages
- Where
- Belgium
- Volunteers
- 167 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Female
Clinical Trial to Assess the Effect of Testosterone in Patients With Poor Ovarian Response (TESTOPRIM)
Trial to determine the absolute and relative efficacy of two follicular preparation regimens with transdermal testosterone during the cycle (s) prior to the initiation of COS (controlled ovarian stimulation) in patients diagnosed…
- Trial name
- TESTOPRIM (NCT03378713)
- Testing
- GROUP 1: Long testosterone, GROUP 2: Short testosterone, GROUP 3: Control
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Unexplained Infertility
A Therapeutic Protocol in Previous Failed ART Patients With High Total NK Cells
patients with previous failed ART cycles with high peripheral NK cells will be divided into 2 groups: one group of patients with previous failed ART cyles will undergo standard treatment but the other group will have in addition…
- Trial name
- NCT03792997
- Testing
- combination therapy for high peripheral NK cells
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Ovarian Hyperstimulation Syndrome, Infertility, Female
Dual Trigger" in IVF Patients at High Risk of Ovarian Hyper Stimulation Syndrome
The present study aims to evaluate whether the use of a "dual trigger" can improve IVF outcomes, compared to GnRH agonist (GnRH-a) alone, in patients at high risk of OHSS undergoing a freeze-all cycle.
- Trial name
- NCT05638529
- Testing
- Pregnyl (1,500) IU, 1.5 mL of normal saline
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Mount Sinai Hospital, Canada
Advanced Age, Recurrent Pregnancy Loss(RPL)
Noninvasive Implantation Potential vs Morphology-Based Selection in IVF Single Blastocyst Transfer
Background: Morphology-based embryo selection cannot detect aneuploidy, which is common in advanced maternal age and recurrent pregnancy loss.
- Conditions
- Advanced Age, Recurrent Pregnancy Loss(RPL), Infertility (IVF Patients), Sequence Analysis
- Trial name
- NICSAI-SBT-RCT (NCT07461077)
- Testing
- NICS-AI, Morphology group
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Phlebitis, Catheter Complications
Peripheral IV Dressing and Phlebitis in Patients From Amazon
Pragmatic, randomized, single-blinded, controlled clinical trial of the effect of dressing and stabilization of peripheral intravenous catheters on the occurrence of phlebitis in adult patients attended at a hospital from the…
- Trial name
- IVDRESAMAZON (NCT04569474)
- Testing
- Transparent dressing
- Where
- 2 sites in Brazil
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hysteroscopy
Use of Music in Reducing Pain During Outpatient Hysteroscopy in Primarily Infertile Patients
The aim of this study is to demonstrate the value of music in outpatient hysteroscopy on patients' level of pain and satisfaction in primarily infertile patients.
- Trial name
- NCT05069025
- Testing
- music, no-music
- Volunteers
- 130 people
- Sponsor
- Cairo University
Recurrent Implantation Failure
ERA in Young Primary Infertile RIF Patients
This study aims to evaluate the clinical efficacy of transcriptome-based endometrial receptivity analysis (tb-ERA) and investigate the molecular mechanisms of abnormal receptivity in young women with unexplained recurrent…
- Trial name
- ERA (NCT07767240)
- Testing
- tb-ERA and personalized embryo transfer
- Where
- China
- Volunteers
- 400 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility (IVF Patients), BMI
BMI Versus Body Fat Percentage - Which is the Better Predictor of Fertility Outcomes in IVF Cycles?
The goal of this prospective observational cohort study is to evaluate whether body composition measured using bioelectrical impedance analysis (BIA) (including measures of body fat% and visceral fat) serve as a better predictor…
- Conditions
- Infertility (IVF Patients), BMI, Bioelectrical Impedance Analysis, IVF Outcomes
- Trial name
- NCT07765368
- Testing
- Measurement of BIA (Body Fat and Visceral Fat Percentage)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Male Infertility
Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: a Randomized, Placebo-controlled, Double-blind Clinical Study
Korean Red ginseng (KRG) has long been applied to various diseases as a health-promoting herbal medicine in Korea. Many clinical studies of ginseng have been performed to elucidate its therapeutic characteristics.
- Trial name
- NCT02204826
- Testing
- Korean Red Ginseng (KRG), Varicocelectomy
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Pusan National University Hospital
Infertility
Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients
In this study, the investigators aimed to evaluate to the efficacy of the needle type used in follicular flushing in oocyte retrieval in the poorest responders undergoing IVF.
- Trial name
- needles(opu) (NCT02391155)
- Testing
- single lumen needle in oocyte retrieval, double lumen needle in oocyte retrieval
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baskent University
Infertility, Embryo Development
Use of G-CSF Supplemented IVF Medium in Patients Undergoing IVF
The purpose of this study is to determine whether in Assisted Reproductive Technologies the use of culture medium supplemented with G-CSF, a growth factor working on stem cells, may improve the embryo implantation and pregnancy…
- Conditions
- Infertility, Embryo Development, IVF
- Trial name
- NCT02651285
- Testing
- G-CSF medium, Control
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Turner Syndrome, Ovarian Insufficiency
Cryopreservation of Ovarian Cortex in Girls With Turner Syndrome
Ovarian insufficiency is common in Turner syndrome related to premature and rapid follicular apoptosis and spontaneous pregnancies are rare in this population.
- Trial name
- CRYO-X0 (NCT01410045)
- Testing
- Ovariectomy
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
Medically Assisted Procreation and Choice of the Embryo: How Far Would French People Like to go
In today's context of bioethics laws revision concerning Medically Assisted Procreation, the investigators focus on the opinion of couples resorting to In Vitro Fertilization on a fundamental, much debated issue ; the choice of…
- Trial name
- NCT04763551
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Male Infertility, Female Infertility
Patient-Centered Implementation Trial for Single Embryo Transfer
Background: The number of multiple pregnancies is considered to be the most important adverse effect of in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI).
- Conditions
- Male Infertility, Female Infertility, Pregnancy
- Trial name
- NCT00315029
- Testing
- evidence based decision aid, Possible reimbursement 4th IVF/ICSI cycle when necessary
- Where
- 2 sites in Netherlands
- Volunteers
- 230 people
- Sponsor
- Radboud University Medical Center