Clinical trials: Infertility, Male
Azoospermia
FSH Treatment for Non-obstructive Azoospermic Patients
Aim of the study is to evaluate the effect of highly purified human follicle-stimulating hormone treatment on the chance of retrieving testicular sperm (sperm retrieval rate) from infertile male patients with non-obstructive…
- Trial name
- NCT02275169
- Testing
- Urofollitropin
- Volunteers
- 200 people
- Sponsor
- Azienda Sanitaria Locale Bari
Azoospermia, Nonobstructive, Infertility, Male
Retrieval of Sperm From Men With Azoospermia Using Ultrasound-guided Rete Testis Aspiration
The objective of this study is to use ultrasound-guided rete testis flushing and aspiration technique to retrieve sperm, non-surgically, from the testes of azoospermic men.
- Trial name
- NCT03291522
- Testing
- Ultrasound-guided rete testis flushing and aspiration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Human Papilloma Virus, Infertility, Male
Detection and Prevalence of Human Papillomavirus (HPV) in Seminal Plasma and/or on Sperm in Men Undergoing Treatment With IVF/ICSI.
This observational study aims to investigate the presence of HPV DNA in semen samples from men undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment.
- Trial name
- NCT06161727
- Testing
- HPV exposure
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Vastra Gotaland Region
Klinefelter Syndrome
Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome
The study seeks primarily to determine whether modulation of systemic and testicular sex steroids balance by aromatase inhibitors will positively affect the metabolic health and spermatogenesis of men with Klinefelter syndrome…
- Trial name
- KLIN-HEALTH (NCT05586802)
- Testing
- Anastrozole, Semaglutide, human chorionic gonadotropin
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Georgios Papadakis
Infertility Unexplained, Oligospermia
Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia
- Trial name
- infertility (NCT06342856)
- Testing
- co enzyme Q10 , L- Carnitine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Infertility, Female, Infertility, Male
Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing
The goal of this observational study is to discern if there is a relationship between timelapse imagery of human oocytes/embryos and PGT results.
- Conditions
- Infertility, Female, Infertility, Male, Infertility, IVF
- Trial name
- NCT06419127
- Testing
- Timelapse incubation and PGT
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Gattaca Genomics
Endometriosis
A Study to Evaluate the Safety and Effectiveness of Three Asoprisnil Doses in the Treatment of Women With Endometriosis
The objective of this study is to determine the safety and effectiveness of three doses of asoprisnil, compared to placebo, in the treatment of women with endometriosis.
- Trial name
- NCT00160446
- Testing
- Asoprisnil
- Volunteers
- 130 people
- Sponsor
- Abbott
Infertility Unexplained
Effect of Oral Zinc Sulfate Supplementation on Enzymes of Urate Pathway
Although many reports have investigated the relationship between subfertility and uric acid levels in semen, to the best of author knowledge, there is no study have been published to yet focus on the effects of asthenospermia…
- Trial name
- NCT03361618
- Testing
- Zinc Sulfate
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Babylon University
Male Infertility
Spermatogonial Stem Cells in Azoospermic Patients: a Comparison Between Obstructive and Non-obstructive Azoospermia
The researchers hypothesized that nonobstructive azoospermia might be associated with a reduction OF SSCs in seminiferous tubules as compared with obstructive azoospermia.
- Trial name
- NCT01178463
- Testing
- Biospecimen staining
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Hillel Yaffe Medical Center
Male Sterility Due to Y-chromosome Deletions
Aneuploidies in Embryos and Spermatozoa From Patients With Y-chromosome Microdeletions
In this study, investigators assess, using Fluorescence in situ Hybridization (FISH) and Comparative Genomic Hybridization (CGH) arrays for Preimplantation Genetic Screening (PGS), the incidence of aneuploidies in spermatozoa and…
- Trial name
- NCT02527954
- Where
- 3 sites in Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Infertility, Male
G-IVF and Sperm Parameters
The aim of this study is to investigate if adding a fixed volume of a physiological solution to a freshly produced sperm sample will affect sperm characteristics.
- Trial name
- NCT05597631
- Testing
- G-IVF PLUS
- Where
- Greece
- Volunteers
- 118 people
- Sponsor
- Vitrolife
Infertility, Male
Clomiphene Citrate in Infertile Men With Idiopathic Oligoasthenozoospermia
The goal of this clinical trial is to learn if drug clomiphene citrate improves sperm parameters in infertile men with idiopathic oligoasthenozoospermia. It will also learn about the safety of clomiphene citrate.
- Trial name
- NCT06564961
- Testing
- Clomiphene Citrate
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Shakeela Ishrat
Infertility, Male
Yeast Cells as Antioxidant-Producing Probiotics
The purpose of this study is to evaluate the efficacy of Baker's yeast extractions , probiotic antioxidant, in scavenging the oxidative stress status mediated damage on sperm motility,progressive motility and vitality as well as…
- Trial name
- Probiotics (NCT02814695)
- Testing
- Vit E, Yeast, Vit C 1
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Periodontitis, Sub-fertility
Association Study Between Periodontal Disease and Male Infertility
The aim of the present study is to examine the association between fertility parameters and the periodontal status of men attending fertility and in vitro fertilization clinic.
- Trial name
- NCT01140945
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Infertility
Quantitative MRI for Functional Imaging of the Testis: A New Methodology for Evaluation of the Infertile Male
Infertility-the inability to conceive despite one year of properly timed unprotected intercourse-is a common problem. Of all types of male factor infertility, non-obstructive azoospermia may be the most difficult for couples.
- Trial name
- NCT02756325
- Testing
- MRI
- Sponsor
- NYU Langone Health
Endometriosis, Quality of Life
Quality of Life in Endometriosis - a Case Control Study
Endometriosis, one of the most common diseases of women during their reproductive period., may present a chronic disabling disease with major impact on women's life.
- Conditions
- Endometriosis, Quality of Life, Pain, Sexuality
- Trial name
- NCT02511626
- Where
- Switzerland
- Volunteers
- 1,267 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Male Infertility
Metabolic Syndrome and Male Infertility
Multidisciplinary, multicentric, cross-sectional study on men in infertile couples who conduct their sperm test through their diagnosis of infertility
- Trial name
- Metasperme (NCT01974947)
- Testing
- Blood sample, sperm sample and clinical examens
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Azoospermia or Severe Oligozoospermia, Infertility
Fertility Restoration With Autografting of Cryopreserved Immature Testicular Tissue
This is a pilot clinical trial to evaluate the feasibility and outcome of autologous transplantation of immature testicular tissue cryopreserved during childhood as a method of fertility preservation for prepubertal boys in case…
- Conditions
- Azoospermia or Severe Oligozoospermia, Infertility, Autologous Transplantation
- Trial name
- TESTIGRAFT (NCT07542626)
- Testing
- autologous transplantation of cryopreserved testicular tissue
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Infertility, Male
Selection of Non Apoptotic Human Sperm for in Vitro Fertilization by Using Magnetic Activated Cell Sorting (MACS)
This clinical study has been organised to help improve the embryo quality in couples having high rate of sperm showing apoptotic signs.
- Trial name
- MACS-HS (NCT03988361)
- Testing
- Magnetic Activated Cell Sorting
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Oligospermia
A Clinical Study of Gulingji Capsule in the Treatment of Idiopathic Oligospermia, Asthenia, and Teratozoospermia
The object of study for patients with idiopathic disease of OAT, the use of multicenter, randomized, double-blind, controlled, prospective clinical research, choose according to row, standard units of idiopathic male infertility…
- Trial name
- NCT05320536
- Testing
- Guilingji Capsule
- Where
- 4 sites in China
- Volunteers
- 240 people
- Sponsor
- Jinling Hospital, China