Clinical trials: Infertility, Male
Male Infertility
A Pilot Study to Evaluate the Effect of Pomegranate Juice on Semen Parameters in Healthy Male Volunteers
How daily consumption of pomegranate juice affects the concentration, morphology or motility of sperm in healthy men.
- Trial name
- NCT01595308
- Testing
- Pomegranate juice
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- POM Wonderful LLC
Unexplained Infertility, Mild Male Factor
Luteal Phase Support With Progesterone Versus Estrogen and Progesterone on Pregnancy Rates
This is a single center, 3 arms, prospective randomized controlled open study to determine the impact of luteal phase support on pregnancy rates in ovarian stimulation and IUI cycles with recombinant FSH in patients with…
- Trial name
- NCT01237535
- Testing
- Luteal support with progesterone only, Luteal support with estrogen + progesterone, Insemination without luteal support
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Rabin Medical Center
Teratozoospermia
Effect of Cannabis Consumption on Sperm Nuclear Quality in Infertile Men
Lifestyle and environmental factors can disrupt development and testicular function. In France, cannabis is the most widely used illicit substance and about 8% of adults between 18 and 64 years smoke cannabis at least once a…
- Trial name
- CANNASPERM (NCT02932527)
- Testing
- Questionnaire about cannabis consumption, blood intake, Semen samples collection
- Where
- 3 sites in France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Rouen
Assisted Reproductive Technology, Assisted Reproductive Technology Outcomes
Sperm Selection Strategies and Male-Factor Phenotypes in ICSI
This retrospective multicentre observational cohort study evaluates clinical and reproductive outcomes associated with different sperm-selection strategies used during intracytoplasmic sperm injection (ICSI), including…
- Trial name
- ANDRO-ART (NCT07825584)
- Testing
- Conventional ICSI, Hyaluronan-Binding Sperm Selection, ZyMōt
- Where
- 10 sites in Poland
- Volunteers
- 12,561 people
- Sponsor
- Center for Reproductive Medicine Bocian
Infertility, Male
Microbiome Influence on Seminal Quality
The microbiome plays an important role in health and in some unknown etiologies. Some previous studies have identified bacteria in semen as a potential factor in male infertility.
- Trial name
- NCT04784260
- Testing
- Microbiome analysis
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Subfertility, Asthenozoospermia
Fertility and the Microbiome
With this study, the investigators want to investigate the microbiome and human papilloma virus (HPV) status of couples with subfertility.
- Trial name
- NCT05328999
- Testing
- Probiotics (Omnibiotic (R))
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Graz
Infertility, Male
Varicocele Repair for Men Undergoing IVF/ICSI
For infertile men undergoing intracytoplasmic sperm injection (ICSI), data from retrospective studies suggested that varicocele repair may be beneficial and associated with improved livebirth and pregnancy rates, however, its…
- Trial name
- Varicocele (NCT04608864)
- Testing
- varicocelectomy
- Volunteers
- 2,000 people
- Sponsor
- Al-Yasmeen Fertility and Gynecology Center
Infertility Unexplained, Infertility, Male
Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
Infertility affects about 10% of all couples and is defined by a failure to achieve a clinical pregnancy within a year of regular unprotected sexual intercourse.
- Conditions
- Infertility Unexplained, Infertility, Male, DNA Damage
- Trial name
- NCT03319654
- Testing
- DNA fragmentation by TUNEL assay
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Asthenozoospermia
The Effect of Royal Vaginal Gel Compared to IUI Technique on Fertility Rate of Women With Low-fertility Husbands
The present Pocock clinical trial study was conducted In the city of Mashhad in Iran between 2015 and 2016. The study inclusion criteria were men with low fertility of sperm motility<25% and total motility <50%…
- Trial name
- NCT03463005
- Testing
- Royal jelly, IUI
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gonabad University of Medical Sciences
Infertility, Male
Single and Double DNA Strand Breaks in Males With Unexplained Infertility Attending Fertility Treatment
The aim of this study is to investigate the extent of double-stranded DNA damage in sperm in men with unexplained infertility.
- Trial name
- NCT05846256
- Testing
- Sperm DNA Fragmentation
- Where
- Denmark
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Male Infertility, Teratospermia
Live Birth Rate Between ICSI and AOA and ICSI Alone in Patients With Severe Teratospermia
The goal of this clinical trial is to compare the live birth rate between intracytoplasmic sperm injection (ICSI) and artificial oocyte activation (AOA) vs intracytoplasmic sperm injection alone in patients with teratospermia.
- Trial name
- NCT06561451
- Testing
- intracytoplasmic sperm injection and artificial oocyte activation, intracytoplasmic sperm injection
- Where
- China
- Volunteers
- 208 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Prostate Cancer
Ablation of Prostate Tissue Utilizing Sterile Water Vapor in Patients With Intermediate Risk Localized Prostate Cancer
The purpose of this research study is to collect information on a new treatment of prostate tissue participants with intermediate risk prostate cancer using a medical device called the Poseidon System.
- Trial name
- NCT04087980
- Testing
- Poseidon System
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Francis Medical Inc.
Subfertility
Stimulated Versus Un-stimulated Intrauterine Insemination Cycles in Couples With Mild Male Factor Infertility
Four hundred and fifty women with mild male factor infertility will be divided into 3 equal groups using computer generated random numbers: Group 1 will have up to 4 stimulated IUI cycles, group 2 will have up to 4 unstimulated…
- Trial name
- NCT02469805
- Testing
- Merional, Choriomon, IUI
- Where
- 2 sites in Egypt
- Volunteers
- 450 people
- Sponsor
- Cairo University
Endometriosis
A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Women With Endometriosis.
The objective of this study is to determine the safety and efficacy of 3 asoprisnil doses (0.5 mg, 1.5 mg, and 5.0 mg) for 12 weeks in women with endometriosis.
- Trial name
- NCT00160433
- Testing
- Asoprisnil
- Volunteers
- 131 people
- Sponsor
- Abbott
Infertility, Nutrition Disorders
Benefits of Walnuts for Male Reproductive Health
Walnuts as a whole food contain polyunsaturated fatty acids, anti-oxidants, and other nutrients essential to sperm development and function.
- Trial name
- NCT01505140
- Testing
- Whole walnuts
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Non-obstructive Azoospermia, Hormone Deficiency
Sperm Retrieval Rates in Non-obstructive Azoospermic Men Subjected to Gonadotropin Therapy
Azoospermia is defined as the complete absence of spermatozoa in the ejaculate. Two-thirds of azoospermic patients have non-obstructive azoospermia (NOA); the latter comprises up to 10% of infertile men overall.
- Conditions
- Non-obstructive Azoospermia, Hormone Deficiency, Hypogonadism, Male, Male Infertility
- Trial name
- NCT05110391
- Testing
- Hormonal Therapy Agent
- Where
- Brazil
- Volunteers
- 616 people
- Sponsor
- ANDROFERT - Clinica de Andrologia e Reproducao Humana
Infertility, Infertility, Male
0.2 ml vs. 0.5 Inseminated Volume in Donor Intrauterine Insemination Cycles: A Prospective RCT
To prospectively determine the most appropriate inseminated volume in donor IUI cycles. It is hypothesized that if the procedure is performed with 0.5 mL instead of 0.2, higher clinical pregnancy rates will be achieved by…
- Conditions
- Infertility, Infertility, Male, Same-Sex Marriage, Parent, Single
- Trial name
- NCT03006523
- Testing
- Intrauterine insemination
- Volunteers
- 293 people
- Sponsor
- Fundacion Dexeus