Clinical trials: Infertility,Female
Diminished Ovarian Reserve, Premature Ovarian Insufficiency
Autologous Platelet-rich Plasma (PRP) Infusion to Improve Outcomes in Women With Ovarian Insufficiency: a Pilot Study
The investigators propose a pilot study to determine if autologous platelet-rich plasma (PRP) improves ovarian reserves and In-vitro fertilisation (IVF) outcomes in women with diminished ovarian reserve / premature ovarian…
- Conditions
- Diminished Ovarian Reserve, Premature Ovarian Insufficiency, Fertility Issues, IVF
- Trial name
- NCT05385848
- Testing
- Autologous Platelet-rich Plasma (PRP) Injection
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- KK Women's and Children's Hospital
Infertility, Miscarriage Threatening
The Constitution and Efficacy of Chinese Medicine of Infertility Male, Female, and Pregnant Female
The project aims to conduct a retrospective study to assess the impact of Traditional Chinese Medicine (TCM) on improving pregnancy rates and preventing miscarriages.
- Trial name
- NCT06393426
- Testing
- Chinese Herb
- Where
- Taiwan
- Volunteers
- 37,611 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Microbial Colonization, Dysbiosis
Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG)
The aim of this study is to determine the efficacy of an oral nutraceutical with probiotics in restore vaginal health.
- Conditions
- Microbial Colonization, Dysbiosis, Fertility Issues
- Trial name
- PROSALVAG (NCT05176535)
- Testing
- FertyBiotic Balance
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Fertypharm
Urinary Catheters, Urinary Tract Infection
Clinical Study on Disposable Sterile Urinary Catheter
This study is a multicenter, randomized controlled study, with the urinary tract infection rate at the time of catheter insertion for 1 week as the primary end point.
- Trial name
- NCT05651217
- Testing
- disposable urinary catheter, super smooth antibacterial urinary catheter
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Shandong Branden Med.Device Co.,Ltd
Infertility
Hyaluronic Acid-enriched Transfer Medium in Single Blastocyst Transfer
The purpose of this study is to compare the live birth rates of high concentration of Hyaluronic Acid (0.5 mg/ml) transfer medium (EmbryoGlue®) to those containing low Hyaluronic Acid concentrations (0.125 mg/ml) (G2 medium) in…
- Trial name
- NCT06492785
- Testing
- High Hyaluronic Acid concentrations (0.5 mg/ml), Low Hyaluronic Acid concentrations (0.125 mg/ml)
- Where
- China
- Volunteers
- 858 people
- Sponsor
- Northwest Women's and Children's Hospital, Xi'an, Shaanxi
Infertility, Female
The Effect of the Mind/Body Program for Fertility, Hungarian Version, on Well-Being and Assisted Reproduction Outcomes
Involuntary childlessness is an emotionally stressful experience; however, psychosocial counseling is typically not available in Hungarian routine fertility care.
- Trial name
- NCT04151485
- Testing
- Mind/Body Program for Fertility (Domar et al., 2011), Fertility Support Program
- Where
- 2 sites in Hungary
- Volunteers
- 177 people
- Sponsor
- Semmelweis University
ICSI
Retrieval Versus Mid-luteal Endometrial Scratching (ES) for Intra Cytoplasmic Sperm Injection (ICSI)
ES is a procedure used to help embryos to implant more successfully after In-Vitro Fertilization (IVF) , ICSI in patients who had failed cycles in spite of transfer of good quality embryos.
- Trial name
- ICSI (NCT03470298)
- Testing
- Endometrial scratching
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Infertility
Evaluation of Efficacy and Safety of Highly Purified Urofollitropin in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program
Evaluate the efficacy and safety of of Highly Purified Urofollitropin for Injection Compared to Recombinant Human Follitropin Alfa for Injection in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program.
- Trial name
- NCT01922193
- Testing
- Highly Purified Urofollitropin, Recombinant Human Follitropin Alfa
- Where
- 11 sites in China
- Volunteers
- 263 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
The Enchanting Symphony of Haptonomy's Impact on Attachment and Spousal Harmony for Women Conceiving Through Infertility Treatment
Pregnancies resulting from infertility treatment are considered normal and 'low-risk' in some countries, they often entail significant stress.
- Trial name
- NCT06274138
- Testing
- haptonomy
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Baskent University
Recurrent Pregnancy Loss, Infertility, Female
Effects of PGS2.0 in Patients With Unexplained RPL
50%-60% of the known causes of recurrent pregnancy loss(RPL) are associated with embryonic aneuploidy, such that preimplantation genetic screening (PGS) on embryos acquired by assisted reproductive treatment should improve the…
- Trial name
- NCT03214185
- Testing
- IVF/ICSI, PGS 2.0, Conventional embryo morphology evaluation
- Where
- China
- Volunteers
- 710 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility (IVF Patients), Infertility
Intra-ovarian CAPA-IVM vs Standard IVM
This prospective study compares two approaches to obtaining mature oocytes for fertility treatment within the same participant. Immature oocytes are first retrieved from the right ovary and matured in the laboratory using a…
- Conditions
- Infertility (IVF Patients), Infertility, Infertility Female
- Trial name
- IO-CAPA (NCT07858435)
- Testing
- CAPA-IVM, In-House CAPA-IVM Pre-Maturation Medium, Minimal-Stimulation OS-IVF
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New Hope Fertility Center
Renal Colic, Urolithiasis
Sterile Water Injection vs Morphine for Renal Colic
This study aims to compare intradermal sterile water injections (ISWI) with intravenous morphine for pain relief in adults with acute renal colic caused by urinary stones.
- Trial name
- ISWI-Morph (NCT07378904)
- Testing
- Single Intradermal Sterile Water Injection, Multiple Intradermal Sterile Water Injections, Intravenous Morphine
- Where
- Tunisia
- Volunteers
- 150 people
- Sponsor
- University Tunis El Manar
Anovulatory Infertility Related to Polycystic Ovary Syndrome
Strategies for Ovulation Induction in Anovulatory Infertile Patients With PCOS
Anovulatory infertility is a common feature of the polycystic ovary syndrome (PCOS). Even if several first-step treatments have been proposed for anovulatory infertile PCOS patients, very few data are available in literature…
- Trial name
- NCT00461643
- Testing
- Clomiphene citrate, metformin, metformin plus clomiphene citrate, gonadotropins
- Where
- 3 sites in Italy
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Endometriosis, Quality of Life
Quality of Life in Endometriosis - a Case Control Study
Endometriosis, one of the most common diseases of women during their reproductive period., may present a chronic disabling disease with major impact on women's life.
- Conditions
- Endometriosis, Quality of Life, Pain, Sexuality
- Trial name
- NCT02511626
- Where
- Switzerland
- Volunteers
- 1,267 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Infertility, Female
The Role of Erzhi Tiangui Formula in Expected POR Women Undergoing IVF-ET
This randomized controlled trial aims to determine whether Erzhi Tiangui Formula can optimize the reproductive outcomes of elderly patients with expected poor ovarian response, and to provide a new approach to traditional Chinese…
- Trial name
- NCT05698550
- Testing
- Erzhi Tiangui Granule
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Shandong University of Traditional Chinese Medicine
Polycystic Ovary Syndrome
Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)
PolysCsytic Ovaries Syndrome (PCOS) is the most frequent endocrinopathy. The first stage of infertility treatment is Clomiphene Citrate which leads to 50 % pregnancies.
- Trial name
- PERCING (NCT00378729)
- Testing
- Metformin and FSHr, Ovarian drilling by FERTILOSCOPY
- Where
- France
- Volunteers
- 252 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Neoplasm, Colorectal Neoplasm
Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer
This trial studies how well a decision aid website works in helping to make decisions about fertility in participants with cancer.
- Conditions
- Breast Neoplasm, Colorectal Neoplasm, Female Reproductive System Neoplasm, Health Care Provider
- Trial name
- NCT03141437
- Testing
- Best Practice, Educational Intervention, Internet-Based Intervention
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- M.D. Anderson Cancer Center
Infertility, Female
Timing of COC Denudation and Embryo Quality
The relation between the timing of COC denudation and oocyte /embryo quality is controversial. The aim of this study is to examine whether timing of denudation of sibling oocytes has any effect on embryo quality.
- Trial name
- NCT03813745
- Testing
- early denudation, late denudation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acıbadem Atunizade Hospital
Infertility, Female
Detection of the Uterine Abnormalities Missed in an Ultrasound Scan and/or Hysterosalpingography Using Hysteroscopy, in Females Presenting With Unexplained Infertility
Hysteroscopy is still considered the gold standard procedure for uterine cavity exploration. Therefore, many specialists have used hysteroscopy as their first-line of routine exam for infertility patients regardless of…
- Trial name
- NCT04179253
- Testing
- office micro hysteroscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Recurrent Implantation Failure, Granulocyte Colony-Stimulating Factor
Intrauterine Infusion of GCSF and Reproductive Outcomes in Infertile Women with History of RIF
Intrauterine infusion of granulocyte colony stimulating factor and reproductive outcomes in infertile women with history of recurrent implantation failure
- Conditions
- Recurrent Implantation Failure, Granulocyte Colony-Stimulating Factor, Infertility
- Trial name
- NCT04998279
- Testing
- Granulocyte Colony-Stimulating Factor
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University