Clinical trials: Infertility,Male
Infertility, Male Infertility
To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.
The goal of this prospective, multicenter randomized controlled clinical trial is to evaluate whether the SwimCount Harvester microfluidic sperm preparation device can achieve equivalent or superior clinical outcomes compared to…
- Conditions
- Infertility, Male Infertility, InVitro Fertilization, Aneuploidy Rate
- Trial name
- NCT07369362
- Testing
- microfludics semen processing device
- Where
- United States
- Volunteers
- 1,600 people
- Sponsor
- MotilityCount aps
Male Infertility
SpermQT Prospective Observational Trial
The goal of the study is to validate the ability of the Epigenetic Sperm Quality Test (SpermQT) to assess a man's sperm quality and corresponding success of infertility treatments.
- Trial name
- SPOT (NCT05966883)
- Where
- 6 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Inherent Biosciences
Male Infertility, Asthenozoospermia
Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility
Male infertility affects millions of males worldwide and is rising in prevalence due to social and environmental conditions. Asthenozoospermia (AZS) and oligoasthenozoospermia (OA) are the major causes of male infertility.
- Conditions
- Male Infertility, Asthenozoospermia, Oligoasthenozoospermia
- Trial name
- NCT05792813
- Testing
- LGYY, LGYY mimetic, WZYZ
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Azoospermia
Testicular Injection of Autologous Stem Cells for Treatment of Patients With Azoospermia
Azoospermia is defined as the complete lack of sperm in the ejaculate. In humans, Azoospermia affects about 1% of the male population and may be seen in up to 20% of male infertility situations.
- Trial name
- NCT02041910
- Testing
- Stem Cells
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hesham Saeed Elshaer
Oligozoospermia, Oligoasthenozoospermia
The Role of Electroacupuncture With Standard Therapy on Sperm Analysis and SOD Levels in Oligozoospermia.
The goal of this clinical trial is to compare in Oligozoospermia Patient. The main questions it aims to answer are: 1. Electroacupuncture therapy and standard therapy can affect oligozoospermia. 2.
- Conditions
- Oligozoospermia, Oligoasthenozoospermia, Oligoasthenoteratozoospermia
- Trial name
- NCT06088693
- Testing
- Electroacupuncture and Standard Therapy
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Universitas Indonesia
Male Infertility
Home Semen Analysis Tests As a Screening Tool for Fertility Patients
Infertility, defined as the inability to conceive after 12 months of regular unprotected intercourse, is estimated to affect 1 in 7 heterosexual couples.
- Trial name
- NCT06188936
- Testing
- ExSeed®, Survey
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Infertility, Female, Infertility
Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI
Female inability to conceive a child. The purpose of this prospective randomized, double-blinded, double dummy, two-arm cross-over study is to investigate the difference on histological, transcriptional and immunological level in…
- Conditions
- Infertility, Female, Infertility, Genital Diseases, Male, Genital Diseases, Female
- Trial name
- NCT03677336
- Testing
- Dydrogesterone Oral Tablet, Micronized progesterone
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Men Carrying 2 Minor Alleles for Choline Dehydrogenase rs12676, Male Infertility
Choline Dehydrogenase and Sperm Function: Effects of Betaine
The ability of sperm to swim is important for normal fertility. Men with a genetic variation in the gene coding for Choline Dehydrogenase (CHDH) have decreased energy production by sperm, and their sperm do not swim normally.
- Trial name
- NCT02122211
- Testing
- Betaine supplement
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Male Infertility
CMV IGG Antibodies in Semen as a Predictor for Blood Testis Barrier Damage
To assess whether the presence of Cytomegalovirus (CMV) Immunoglobulin G (IGG) antibodies in semen is a reliable predictor of male subfertility or infertility.
- Trial name
- NCT05302856
- Testing
- Blood test (CMV IGG, Anti sperm antibody, Testosterone levels)
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Oligospermia, Azoospermia
Clinical Research on Effectiveness and Safety of Treatment of Severe Oligospermia or Azoospermia With uFSH
The purpose of this study is to determine whether uFSH is effective and safe in the treatment of male patients with severe oligospermia or azoospermia.
- Trial name
- NCT02307994
- Testing
- 75IU uFSH
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Turner Syndrome, Ovarian Insufficiency
Cryopreservation of Ovarian Cortex in Girls With Turner Syndrome
Ovarian insufficiency is common in Turner syndrome related to premature and rapid follicular apoptosis and spontaneous pregnancies are rare in this population.
- Trial name
- CRYO-X0 (NCT01410045)
- Testing
- Ovariectomy
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthenozoospermia
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10.
- Trial name
- NCT07252518
- Testing
- Coenzyme Q 10, Pentoxifylline 400 MG Oral Tablet
- Where
- Bangladesh
- Volunteers
- 56 people
- Sponsor
- Mst.Sumyara Khatun
Infertility, Male, Varicocele
IVF Outcomes After Varicocele Repair
Infertility has been estimated to affect from 6-18% of couples trying to conceive. In 20-30% of cases, the problem is with the male.
- Conditions
- Infertility, Male, Varicocele, In Vitro Fertilization
- Trial name
- NCT03090438
- Testing
- Varicocele embolization
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Ureterolithiasis, Pain
Sterile Water Injections for Relieving Ureterolithiasis Pain
Ureterolithiasis pain is a severe condition for which it takes some 30 minutes for standard treatment to yield maximal pain relief, a period during which the patient suffers severe to intolerable pain.
- Trial name
- NCT01412840
- Testing
- Diclofenac and sterile water injections, Diclofenac and isotonic saline
- Where
- Sweden
- Sponsor
- University of Skövde
Obesity, Hypoandrogenism
Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism
Hypogonadism is a clinical condition that can be associated with obesity in man. Controversy exists regarding if its a condition that needs to be treated.
- Trial name
- NCT02380755
- Testing
- Clomiphene Citrate
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- University of Sao Paulo
Subfertility
Stimulated Versus Un-stimulated Intrauterine Insemination Cycles in Couples With Mild Male Factor Infertility
Four hundred and fifty women with mild male factor infertility will be divided into 3 equal groups using computer generated random numbers: Group 1 will have up to 4 stimulated IUI cycles, group 2 will have up to 4 unstimulated…
- Trial name
- NCT02469805
- Testing
- Merional, Choriomon, IUI
- Where
- 2 sites in Egypt
- Volunteers
- 450 people
- Sponsor
- Cairo University
Azoospermia
Testicular Evaluation of Azoospermia Using Micro-Ultrasound
The investigation is a small feasibility study to determine whether there are imaging features related to the seminiferous tubules in the testes under microultrasound.
- Trial name
- NCT06941922
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Paul Shin
Azoospermia, Elasticity Imaging Techniques
Testicular Elastography for Microscopic Testicular Sperm Extraction
Before commencing our study, we obtained approval from the local ethics committee. The study focused on patients who visited our urology outpatient clinic for infertility between January 2020 and March 2021.
- Conditions
- Azoospermia, Elasticity Imaging Techniques, Fertility Preservation
- Trial name
- NCT06524258
- Testing
- testicular elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Uşak University
Male Infertility
Effect of Antioxidant Probiotic Administration on Seminal Quality and Reproductive Outcomes.
The quality of semen plays a fundamental role in correct fertilization and development of normal embryos that result in a live birth. Unfortunately, semen quality has declined during the last decades, and reduced more and more.
- Trial name
- NCT04585984
- Testing
- Experimental - Probiotic
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fundación IVI
Male Infertility, Azoospermia, Nonobstructive
Management of Non Obstructive Azoospermia in Men
this study predicts the factors of successful micro testicular sperm extraction in azoospermia patients in male infertility
- Trial name
- azoospermia (NCT06983626)
- Testing
- micro-dissection testicular sperm extraction
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South Valley University