Clinical trials: Infertility,Male
Infertility, Male, Testosterone Deficiency
Determining the Reproductive Health of Men Post-COVID-19 Infection
Study rationale 1. An increasing proportion of the worldwide population is being infected with COVID-19. 2. There are ongoing and currently unanswered safety concerns about the effects of COVID-19 on reproductive health. 3.
- Trial name
- NCT04414904
- Testing
- Exposure: Covid-19 infection
- Where
- United Kingdom
- Sponsor
- Imperial College London
Male Infertility Due to Antisperm Antibody
Influence of Inguinal Hernia Repair on Sperm Autoimmunity
Influence of inguinal hernia repair on sperm autoimmunity using MAR test
- Trial name
- SPERMAR (NCT04591470)
- Testing
- Mar test
- Where
- Italy
- Volunteers
- 2,415 people
- Sponsor
- Istituto Clinico Humanitas
Infertility, Male
Varicocele Repair for Men Undergoing IVF/ICSI
For infertile men undergoing intracytoplasmic sperm injection (ICSI), data from retrospective studies suggested that varicocele repair may be beneficial and associated with improved livebirth and pregnancy rates, however, its…
- Trial name
- Varicocele (NCT04608864)
- Testing
- varicocelectomy
- Volunteers
- 2,000 people
- Sponsor
- Al-Yasmeen Fertility and Gynecology Center
Azoospermia, Oligozoospermia
Autologous Adipose-Derived Adult Stromal Vascular Cell Administration for Male Patients With Infertility
Severe Oligospermia (oligozoospermia) refer to semen with a low concentration of sperm and is a common finding in male infertility.
- Trial name
- NCT03762967
- Testing
- Lipoaspiration and SVF introduction., Standard therapy.
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Infertility,Male, Vitamin D Deficiency
Vitamin D and Human Sperm DNA Fragmentation
The purpose of this study will be to investigate if there is a correlation between Vitamin D levels and Sperm DNA Fragmentation. This is a prospective, cohort study.
- Trial name
- NCT03829943
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Sanford Health
Male Infertility
Validation of New Devices Against Ambient Electromagnetic Radiation
Project Summary Cell phones have become indispensable devices in the investigator's daily life. These phones operate between 400 and 2000 MHz frequency bands and emit radiofrequency electromagnetic waves (EMW).
- Trial name
- NCT04541459
- Testing
- new device against ambient electromagnetic radiation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Waveguard GmbH
Infertility, Male
Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients
The purpose of this study is to compare semen parameters with in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) when male factor infertility patients abstain from ejaculation more than 48 hours (routine care)…
- Trial name
- NCT04206800
- Testing
- Ejaculatory abstinence less than 24 hours
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boston IVF
Infertility, Infertility, Male
Randomized, Standard-Controlled, Study to Evaluate the Ohana IVF Sperm Preparation Kit, SPeRtility IVF Next Generation
Multi-centered, randomized controlled study, evaluating the safety and efficacy of the Ohana IVF Sperm Preparation Kit vs. a standard IVF sperm preparation kit.
- Trial name
- SPRING (NCT04142112)
- Testing
- Ohana IVF Sperm Preparation Kit (OHB035), Standard IVF Preparation Kit (OHB037)
- Where
- 7 sites in United States
- Volunteers
- 83 people
- Sponsor
- Ohana BioSciences
Male Infertility
Vitamin D Level vs Semen Parameters
Infertility is defined as the inability of a sexually active couple to conceive after 1 year of regular intercourse without contraception, affects approximately 15% of couples, and male factors are the cause in 20% -50% of cases.
- Trial name
- NCT03167008
- Testing
- semen sample, blood sample
- Volunteers
- 60 people
- Sponsor
- Assiut University
Infertility, Male
Reproductive Outcomes of Different Sperm Selection Techniques for ICSI Patients With Abnormal Sperm DNA Fragmentation.
Comparing the reproductive outcomes of different sperm selection techniques; Density gradient centrifugation (DGC), Testicular sperm (Testi), Physiological ICSI (PICSI), and Magnetic activated cell sorting (MACS) in abnormal…
- Trial name
- NCT04482517
- Testing
- Density Gradient Centrifugation, Physiological ICSI, Magnetic activated cell sorting
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Ganin Fertility Center
Infertility, Male
Sperm DNA Damage to Intracytoplasmic Sperm Injection Outcome
In the current era of assisted reproductive techniques where technology can help overcome defects in sperm function, the value of semen analysis has become even more inaccurate.
- Trial name
- NCT03129243
- Testing
- Sperm DNA integrity by flow cytometry
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Infertility, Male, Depression
Impact of Duloxetine on Male Fertility
The investigators are conducting a placebo-controlled, randomized control trial with duloxetine in healthy, fertile men not previously on any antidepressants.
- Trial name
- NCT03038867
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility, Male
Role of Nutritional Support in Idiopathic Male Infertility
Approximately 100 males with idiopathic infertility and oligo- and/or astheno- and/or and/or teratozoospermia and fertile woman will take a Test dietary supplement (TDS), containing carnitine, vitamins and trace elements (active…
- Trial name
- NCT03588949
- Testing
- Dietary Supplement with L-carnitine (FertilHom), Control Dietary Supplement
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- NATURAmedicatrix Sàrl
Infertility Unexplained, Infertility, Male
Comparison of the Effect of Microchip and Density Gradient Methods in Intrauterine Insemination Cycles
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT04144244
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility, Male
Evaluation of Sperm Selection Technique Using Hyaluronic Acid Binding in Intra-cytoplasmic Sperm Injection (ICSI)
In vitro sperm selection for ICSI is important as it has a direct influence on the paternal contribution of preimplantation embryogenesis. Various laboratory tests were developed to assess the functions of the spermatozoa.
- Trial name
- NCT03999372
- Testing
- Hyaluronan binding system, ICSI
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- ClinAmygate
Male Infertility, Cancer
Epigenetic and Genetic Effects in Cancer Patients: Analysis Pre and After Treatment
The prognosis in cancer patients has improved over the years. Survivor rates have increased significantly, and paternity has become an important concern in more than 50% of young male survivors.
- Conditions
- Male Infertility, Cancer, Epigenetic Disorder
- Trial name
- NCT04200118
- Testing
- Observational
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- IVI Barcelona
Male Infertility
Myo-inositol and an Antioxidant Mix for the Treatment of Vietnamese Infertile Men
The aim of this study is to evaluate if Myo-inositol, N-Acetyl-Cysteine plus a cocktail of antioxidants could be able to increase spermatozoa parameters and reduce semen hyper-viscosity
- Trial name
- NCT03726450
- Testing
- Andrositol Plus
- Where
- Vietnam
- Volunteers
- 55 people
- Sponsor
- Andrology and Fertility Hospital of Hanoi
Male Infertility
Body Mass Index and Age Correlate With Antioxidant Supplementation Effects on Sperm Quality
Spermatozoa are vulnerable to lack of energy and oxidative stress as a result of elevated levels of reactive oxygen species. Therefore, it is essential that appropriate nutrients are available during maturation.
- Trial name
- NCT04177667
- Testing
- Proxeed
- Volunteers
- 104 people
- Sponsor
- University of Roma La Sapienza
Infertility, Female, Infertility, Male
Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles
The aim of this randomized controlled trial is to compare the efficacy of oral dydrogesterone vs. micronized vaginal progesterone for luteal phase support in frozen-thawed embryo transfer cycles.
- Conditions
- Infertility, Female, Infertility, Male, Embryo Transfer, Fertilization in Vitro
- Trial name
- NCT04124913
- Testing
- Dydrogesterone 10 MG Oral Tablet, Progesterone Vaginal Gel [Crinone]
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial Sisli Hospital, Istanbul
Male Infertility, Infertility, Male
The Evaluation of the Effect of Microfluidic Sperm Sorting Chip 'Labs-on-a-chip' on IVF Success in Male Factor
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT03960229
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University