Clinical trials: Infertility,Male
Infertility, Female, Infertility, Male
Cell Free Preimplantation Genetic Testing
This study aims to develop preimplantation genetic testing methods from embryo culture media (cell free). Genetic testing of culture media will be compared to conventional methods based on embryo biopsies.
- Trial name
- NCT04628507
- Testing
- Spent media collection
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Genomic Prediction Inc.
Non Obstructive Azoospermia, Hypogonadism
Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism
Hypothesis: Prescribed clomiphene citrate to azoospermic patients with hypoandrogenism could improve the sperm retrieval in either fresh sperm or after surgical sperm extraction.
- Trial name
- NCT02137265
- Testing
- Clomiphene
- Where
- Spain
- Sponsor
- University of Illinois Chicago
Urologic Diseases, Male Infertility
Protocol N. 2014 - Observational Study on the Quality of Life of Outpatients
Prospective observational study on the quality of life of patients attending general urology, sexual medicine, reproductive medicine, functional urology, neuro-urology and uro-oncology clinics.The data relating to the clinical…
- Conditions
- Urologic Diseases, Male Infertility, Sexual Medicine
- Trial name
- NCT06193850
- Testing
- Observation during time
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Testicular Cancer
WEST-KOaST Study: WES Analysis of Testicular Cancer Patientsand Their First-degree Family Members
The project aims to identify the possible risk factors regarding the onset of the disease and to evaluate genes and gene modifications responsible for the onset od testicular cancer.
- Trial name
- West-KOaSt (NCT06142500)
- Testing
- Analysis of biological samples of saliva from testicular cancer patients and from their first-degree family members
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Male Infertility
Impact of Antioxidant Treatment on DNA Fragmentation Index
Increased sperm DNA Fragmentation Index implies decreased male fertility in vivo and in vitro. There is need for developing new strategies for improvement of male fertility.
- Trial name
- Androferti (NCT03466229)
- Testing
- Androferti
- Volunteers
- 79 people
- Sponsor
- Region Skane
Infertility
Prospective, Randomized Trial Comparing ICSI to Insemination for Non-Male Factor Patients Undergoing PGT-A
Intracytoplasmic sperm injection (ICSI) is a procedure performed during in vitro fertilization (IVF) in which a single sperm is injected directly into an oocyte.
- Trial name
- NCT05548101
- Testing
- ICSI
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Fertility Center
Abnormal Spermatogenesis, Azoospermia
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility
The aim of this study was to assess meiotic recombination in primary spermatocytes, synaptonemal complex length and the correlation with chromosomal abnormalities in testicular spermatozoa from infertile men with idiopathic…
- Trial name
- NCT02339272
- Testing
- non interventional
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Igenomix
Infertility (IVF Patients), Male Fertility
Functional Development and Clinical Validation of a Diagnostic Tool Based on Artificial Intelligence for the Assessment of Sperm Quality and the Selection of the Optimal In Vitro Fertilisation (IVF) Treatment
Infertility is a growing global health problem affecting millions of couples worldwide, with male infertility accounting for approximately half of all cases.
- Conditions
- Infertility (IVF Patients), Male Fertility, Sperm Selection
- Trial name
- NCT07185984
- Testing
- Sperm sellection, DIAGNOSIS TOOL
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Gonadal Dysfunction, Gonadal Failure
Fertility Enhancement Through Regenerative Treatment in Ovaries and Testes
This study investigates the safety and efficacy of stem cell or stem cell-derived exosome therapy for gonadal failure, including testicular failure, hypogonadism, ovarian insufficiency, and premature ovarian failure (POF).
- Conditions
- Gonadal Dysfunction, Gonadal Failure, Azoospermia, Testosterone Deficiency
- Trial name
- FERTILE (NCT06841328)
- Testing
- Stem cells
- Where
- United Arab Emirates
- Volunteers
- 60 people
- Sponsor
- Jumeirah American Clinic
Male Infertility, Epigenetic Disorder
Human Sperm Epigenetics in Embryonic Development.
A total of 60 men (40 with a history of infertility and treatment with assisted reproduction and 20 infertile controls achieving conception naturally) will be asked to provide at least one semen sample each for conventional semen…
- Trial name
- EPI (NCT04256668)
- Testing
- Obtaining one or semen samples
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, Hypoandrogenism
Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism
Hypogonadism is a clinical condition that can be associated with obesity in man. Controversy exists regarding if its a condition that needs to be treated.
- Trial name
- NCT02380755
- Testing
- Clomiphene Citrate
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- University of Sao Paulo
Male Infertility
Myo-inositol and an Antioxidant Mix for the Treatment of Vietnamese Infertile Men
The aim of this study is to evaluate if Myo-inositol, N-Acetyl-Cysteine plus a cocktail of antioxidants could be able to increase spermatozoa parameters and reduce semen hyper-viscosity
- Trial name
- NCT03726450
- Testing
- Andrositol Plus
- Where
- Vietnam
- Volunteers
- 55 people
- Sponsor
- Andrology and Fertility Hospital of Hanoi
Male Infertility
Spermotrend in the Treatment of Male Infertility
The purpose of this study is to determine whether the administration of the dietary supplement Spermotrend improves spermatogenesis parameters in subjects with male infertility unrelated to major testicular conditions.
- Trial name
- NCT00975117
- Testing
- Spermotrend
- Where
- Cuba
- Volunteers
- 86 people
- Sponsor
- Catalysis SL
Male Infertility
Administration of Antioxidants to Infertile Men and Sperm Quality
The purpose of this randomized clinical trial is to assess the effect of oral antioxidant administration to infertile men, by evaluating semen variables, sperm DFI and levels of ROS.
- Trial name
- NCT04256278
- Testing
- Spermotrend
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Aristotle University Of Thessaloniki
Inguinal Hernia Bilateral
Inguinal Hernia Repair and Male Fertility
General objective: To evaluate the fertility of adult men submitted to bilateral herniorrhaphy with mesh placement by the Lichtenstein and laparoscopic approaches
- Trial name
- NCT05799742
- Testing
- Bilateral hernioplasty
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Azoospermia or Severe Oligozoospermia, Infertility
Fertility Restoration With Autografting of Cryopreserved Immature Testicular Tissue
This is a pilot clinical trial to evaluate the feasibility and outcome of autologous transplantation of immature testicular tissue cryopreserved during childhood as a method of fertility preservation for prepubertal boys in case…
- Conditions
- Azoospermia or Severe Oligozoospermia, Infertility, Autologous Transplantation
- Trial name
- TESTIGRAFT (NCT07542626)
- Testing
- autologous transplantation of cryopreserved testicular tissue
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Infertility
Mechanisms of Infertility and Hormonal Changes in Patients With Chronic Kidney Disease
Patients with chronic kidney disease (both men and women), especially those with terminal renal failure, manifest infertility. There has been demonstrated several hormonal changes in patients on dialysis.
- Trial name
- NCT01294904
- Where
- 2 sites in Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University
Prostate Cancer, Sexual Dysfunction and Infertility
Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer
RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners.
- Conditions
- Prostate Cancer, Sexual Dysfunction and Infertility, Sexuality
- Trial name
- NCT01982058
- Testing
- communication intervention, counseling intervention, nutrition intervention
- Where
- 6 sites in United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Infertility
Impact of an Antioxidant Alimentary Complement on Sperm Data
Male infertility is a multifactorial disease process with a number of potential contributive causes. Considering the majority of male infertility cases are due to deficient sperm production of unknown origin, environmental and…
- Trial name
- NCT01841034
- Testing
- Conceptio EA
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice