Clinical trials: Infertility,Male
Prostate Cancer
Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
RATIONALE: Nerve-sparing radical prostatectomy with nerve grafting followed by standard therapies for erectile dysfunction may be effective in helping patients with prostate cancer improve sexual satisfaction and quality of life.
- Trial name
- NCT00080808
- Testing
- Alprostadil (E1), Papaverine, Phentolamine mesylate
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- M.D. Anderson Cancer Center
Infertility, Quality of Life
Decisional Process in Male Fertility Preservation
The survey analyses how to improve the decision-making process for fertility preservation in the pediatric population based on 1. patient and parent feelings about fertility preservation counselling 2.
- Conditions
- Infertility, Quality of Life, Cancer
- Trial name
- NCT02411214
- Testing
- survey
- Volunteers
- 348 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Infertility, Infertility, Female
Developmental Epidemiological Study of Children Born Through Reproductive Technology
DESCRT will be a long-term study that both looks back in time, at successful pregnancies, and forward in time at early pregnancy and long-term as these children grow.
- Conditions
- Infertility, Infertility, Female, Infertility, Male, Infertility Primary
- Trial name
- DESCRT (NCT03799107)
- Where
- United States
- Volunteers
- 2,020 people
- Sponsor
- University of California, San Francisco
Male Infertility
Semen Analysis and Insight Into Male Infertility
Semen analysis is the cornerstone for the valuation of the male partner in the infertile couples. This test has been standardized throughout the world through the World Health Organization (WHO) since the1970s by producing…
- Trial name
- NCT04178954
- Testing
- semen fluid analysis
- Volunteers
- 1,000 people
- Sponsor
- Batool Mutar
Isolated Hypogonadotropic Hypogonadism, Kallmann Syndrome
Efficacy and Safety of Long Term Use of hCG or hCG Plus hMG in Males With Isolated Hypogonadotropic Hypogonadism (IHH)
This study will evaluate the efficacy and safety of long term use of hCG alone or hCG plus hMG in the treatment of male patients with isolated hypogonadotropic hypogonadism (IHH).
- Conditions
- Isolated Hypogonadotropic Hypogonadism, Kallmann Syndrome, Infertility
- Trial name
- IHH (NCT03687606)
- Testing
- Human Chorionic Gonadotropin, human menopausal gonadotropin
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Tongji Hospital
Oligospermia, DNA Damage
Comparison of ICSI Outcomes in Cycles Using Testicular and Ejaculate Sperm From Couples With High SDF
In patients with oligospermia in the ejaculate or previous ICSI failures if it concurs with high DNA fragmentation, it has been hypothesized that the use of sperm obtained from the testicle would improve the clinical results…
- Conditions
- Oligospermia, DNA Damage, IVF, ICSI
- Trial name
- NCT04795440
- Testing
- Testicular biopsy
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Fundación IVI
Infertility, Female, Infertility, Male
Effects of Antioxidant Supplementation of Culture Media on IVF Embryos
The goal of this clinical trial is to investigate the impact of repeated antioxidant supplementation on blastocyst utilization and expansion rates in embryos under different oxygen concentrations.
- Trial name
- NCT05919186
- Testing
- EmbryORP®, O2 tension 20%, O2 tension 5%
- Where
- Mexico
- Volunteers
- 293 people
- Sponsor
- Liliana Berenice Ramírez Domínguez
Male Infertility, Leukopenia
Male Infertility Related With Post Infection Inflammatory Syndrome
BACKGROUND: One couple out of 6 consults for infertility during their sexual life. In 60% of cases a male factor is associated or is the main infertility factor.
- Conditions
- Male Infertility, Leukopenia, Postinfection Inflammation, Oxidative Stress
- Trial name
- SIGMA (NCT01407484)
- Testing
- Prednisone
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Male Infertility
Validation of New Devices Against Ambient Electromagnetic Radiation
Project Summary Cell phones have become indispensable devices in the investigator's daily life. These phones operate between 400 and 2000 MHz frequency bands and emit radiofrequency electromagnetic waves (EMW).
- Trial name
- NCT04541459
- Testing
- new device against ambient electromagnetic radiation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Waveguard GmbH
Antioxidants, Infertility, Male
Oxidative Stress In Semen And Male Infertility
The proposed research aims to study the effects of antioxidant therapy, commonly used in male infertility treatment, on semen analysis.
- Conditions
- Antioxidants, Infertility, Male, Semen Quality
- Trial name
- NCT03464656
- Testing
- Fairhaven Pro for men, Semen analysis, Sperm DNA fragmentation
- Where
- Qatar
- Volunteers
- 100 people
- Sponsor
- Hamad Medical Corporation
Non Obstructive Azoospermia, Hypogonadism
Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism
Hypothesis: Prescribed clomiphene citrate to azoospermic patients with hypoandrogenism could improve the sperm retrieval in either fresh sperm or after surgical sperm extraction.
- Trial name
- NCT02137265
- Testing
- Clomiphene
- Where
- Spain
- Sponsor
- University of Illinois Chicago
Klinefelter Syndrome, Hypergonadotropic Hypogonadism
Androgen for Leydig Cell Proliferation
Patients with infertility often presents alterations at ultrasonographic examination of the testis. These alterations include a much higher incidence of small, multiple, non-palpable hypoechoic micro-nodules that can show…
- Conditions
- Klinefelter Syndrome, Hypergonadotropic Hypogonadism, Hypergonadotropic Azospermia, Hypergonadotropic Cryptozoospermia
- Trial name
- ALCeP (NCT01206270)
- Testing
- Testosterone undecanoate, Castor Oil
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- University of Roma La Sapienza
Gynecological Disorders, Male Infertility
Biobank Aimed to Study Gynecological Pathologies, of Male and Female Infertility and Pregnancy Pathologies
The REPRO-Biobank has been established at San Raffaele Hospital in Milan for the purpose of collecting and preserving human biological samples and associated data.
- Conditions
- Gynecological Disorders, Male Infertility, Female Infertility, Pregnancy
- Trial name
- NCT07265908
- Testing
- Blood sampling
- Where
- Italy
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Oligoasthenoteratozoospermia, Male Infertility
Comparative Efficacy of Antioxidants Alone Versus Combined Therapy With SERMs or FSH in Normogonadotropic Idiopathic OAT Patients: A Randomized Controlled Trial
This prospective randomized controlled trial will compare three treatment approaches for men with idiopathic oligoasthenoteratozoospermia (OAT), a condition characterized by abnormalities in sperm count, movement, and shape…
- Trial name
- NCT07862725
- Testing
- Antioxidants + Clomiphene Citrate, Antioxidants + FSH, Antioxidants Alone
- Where
- Qatar
- Volunteers
- 360 people
- Sponsor
- Hamad Medical Corporation
Infertility, Female, Infertility, Male
Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles
The aim of this randomized controlled trial is to compare the efficacy of oral dydrogesterone vs. micronized vaginal progesterone for luteal phase support in frozen-thawed embryo transfer cycles.
- Conditions
- Infertility, Female, Infertility, Male, Embryo Transfer, Fertilization in Vitro
- Trial name
- NCT04124913
- Testing
- Dydrogesterone 10 MG Oral Tablet, Progesterone Vaginal Gel [Crinone]
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial Sisli Hospital, Istanbul
Male Infertility
Personalized Signature of Chronic Inflammation and Early Aging Predictive of the Comorbidities in Infertile Men
The aim of the project is identify new biomarkers and/or prognostic factors in order to develop personalized strategies to prevent the onset of tumor and/or non tumor comorbidity in infertile men.
- Trial name
- NCT06082362
- Testing
- Collection of clinical and biological material
- Where
- Italy
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Testis, Infertility
TNFSF11 Inhibition and Fertility: a Prospective Study
The receptor activator of NF-kB ligand (RANKL) system is considered important for bone homeostasis and comprises three important factors.
- Conditions
- Testis, Infertility, Sperm
- Trial name
- NCT02422108
- Testing
- Denosumab
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Martin Blomberg Jensen
Varicocele
Evaluation of Fertitonex Effects on Semen Parameters in Clinical Varicocele Patient.
The aim of the study is to evaluate the Fertitonex effects on semen parameters in clinical varicocele patients.
- Trial name
- NCT06718426
- Testing
- Fertitonex capsule
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Menoufia University
Infertility, Female, Infertility, Male
Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing
The goal of this observational study is to discern if there is a relationship between timelapse imagery of human oocytes/embryos and PGT results.
- Conditions
- Infertility, Female, Infertility, Male, Infertility, IVF
- Trial name
- NCT06419127
- Testing
- Timelapse incubation and PGT
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Gattaca Genomics
Hypogonadism, Opioid-Related Disorders
Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration
The purpose of this randomized controlled clinical trial is to evaluate the effects of clomiphene citrate compared to placebo (substance without active medication) in men who are taking pain medication (opioids) for chronic pain…
- Conditions
- Hypogonadism, Opioid-Related Disorders, Male Infertility
- Trial name
- NCT01880086
- Testing
- Clomiphene citrate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Weill Medical College of Cornell University