Clinical trials: Infertility/Sterility
- Condition Infertility/Sterility
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Endometriosis
Open Label Immunotherapy of Endometriosis
Endometriosis is a chronic gynecological disease characterized by sustained painful symptoms that are responsible for a decline in the quality of life of sufferers.
- Trial name
- NCT03340324
- Testing
- V-Endo
- Where
- Mongolia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Immunitor LLC
Infertility
Prospective Paired Study on the Effectiveness of MitoGrade
Chromosomal abnormalities are a major cause of pregnancy loss. Preimplantation Genetic Screening (PGS) using Next Generation Sequencing (NGS) allows the effective detection of these abnormalities and improves clinical outcomes.
- Trial name
- NCT02673125
- Testing
- MitoGrade
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Reprogenetics
Infertility, Male Factor
FemaSeed LOCAL Artificial Insemination Trial
Brief Summary: The objectives of the trial are to evaluate the safety and effectiveness of the FemaSeed Localized Directional Insemination for artificial insemination, now known as the FemaSeed Intratubal Insemination since FDA…
- Trial name
- LOCAL (NCT04968847)
- Testing
- FemaSeed Localized Directional Insemination
- Where
- 18 sites in United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Infertility, Female, Fertility Disorders
Comparison of Two PPOS Models for Pituitary Suppression
The scarcity of evidence regarding the interchangeable use of different progestogens poses challenges, particularly in international egg donation and fertility preservation programs where standardizing protocols is crucial for…
- Trial name
- NCT06304220
- Testing
- Cerazet
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- NextFertility
Infertility
Predictive Factors for Ovarian Stimulation Using a Fixed Daily Dose of 200 IU Recombinant FSH (Study 142003)(P05696)
The success of assisted reproductive technologies (ART) is critically dependent on optimizing protocols for controlled ovarian stimulation to provide adequate numbers of good quality oocytes and embryos.
- Trial name
- Xpect (NCT00778999)
- Testing
- Marvelon
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Male Infertility
A Novel Sperm Selection Method Provides Advantages Over Conventional Approaches
The goal of this clinical trial is to know if a novel sperm selection device (CA0) has a similar performance than the standard selection method in teratozoospermic and azoospermic men.
- Trial name
- NCT06545318
- Testing
- Density Gradient Centrifugation, CA0 chamber
- Where
- Mexico
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Center of Innovation Technology & Reproductive Medicine
Infertile Women Undergoing IVF or ICSI
Observational Study to Develop Dosing Chart
To confirm the predictors based on patient specific characteristics and ovarian response and develop dosing chart when Follitrope™ PFS is administered to infertility women patients.
- Trial name
- NCT04227171
- Where
- South Korea
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- LG Chem
Microbial Colonization, Dysbiosis
Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG)
The aim of this study is to determine the efficacy of an oral nutraceutical with probiotics in restore vaginal health.
- Conditions
- Microbial Colonization, Dysbiosis, Fertility Issues
- Trial name
- PROSALVAG (NCT05176535)
- Testing
- FertyBiotic Balance
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Fertypharm
Fertility, Infertility
New Strategies to Evaluate the Reproductive Tract Microbiome
The goal of this observational study is to evaluate alternative less invasive sampling methods for the analysis of the endometrial microbiome.
- Conditions
- Fertility, Infertility, Reproductive Health, Microbiome Analysis
- Trial name
- niMICROBIOME (NCT06920797)
- Testing
- Reproductive tract microbiome analysis
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Igenomix
Infertility
Comparison of Transfers of Fresh and Thawed Embryos in High Responder Patients
This study tests the hypothesis that controlled ovarian stimulation impairs endometrial receptivity in high responders.
- Trial name
- NCT00963079
- Testing
- Embryo cryopreservation, Fresh blastocyst transfer
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
InFertility
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH
This study will be performed in approximately 132 women with anovulatory/oligoovulatory infertility.
- Trial name
- NCT00296465
- Testing
- Pulsatile gonadotropin-releasing hormone (GnRH), Clomiphene Citrate
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Women Infertility
Myo-inositol/D-chiro-inositol Ratio in Follicular Fluid
Considering the importance assumed by follicular microenvironment for a proper oocyte development, this study is a prospective observational clinical trial which aims to evaluate whether the embryo blastocyst quality may be…
- Trial name
- NCT03055442
- Testing
- Dosage of myo-inositol, Dosage of D-chiro-inositol
- Where
- Greece
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Lo.Li.Pharma s.r.l
Healthy
Bioequivalence Trial of Liquid Versus Freeze-Dried Pergoveris® in Pituitary Suppressed Healthy Premenopausal Female Subjects
Some women cannot have children because they cannot produce enough follicle stimulating hormone (FSH) and luteinising hormone (LH).
- Trial name
- NCT02317809
- Testing
- Liquid pergoveris, Freeze-dried pergoveris
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
The Pharmacokinetic and Bioavailability of GenSci094 Before and After a Change in Manufacturing Site
The bioavailability study is intended to evaluate the pharmacokinetic (PK) characteristics and the bioavailability of the two formulations in humans before and after the change of production site, in order to assess the possible…
- Trial name
- NCT06095206
- Testing
- GenSci094
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Female Infertility, Reproductive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Female Fertility
This study evaluates the effects of a daily dietary supplement (WeNatal For Her) on markers of female fertility, reproductive health, and sexual health over three menstrual cycles.
- Conditions
- Female Infertility, Reproductive Health, Fertility, Hormonal Imbalance
- Trial name
- NCT07740187
- Testing
- WeNatal For Her Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Male Infertility
A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0
The purpose of this study is to determine if elevations in oxidative stress, as measured by oxidation-reduction potential (ORP), can distinguish between semen samples from men with abnormal semen parameters from those with normal…
- Trial name
- NCT02839447
- Testing
- Diagnostic
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aytu BioPharma, Inc.
Topical Antisepsis
Test for Pre Operative Skin Preparations
Compare 2 application techniques of ChloraPrep Swabstick--3 swabsticks at once versus 3 swabsticks used sequentially. Hibiclens applied according to the manufacturer's directions.
- Trial name
- NCT00799812
- Testing
- CHG 2% w/v & IPA 70% v/v, swabstick (3 @ once)., CHG 2% w/v & IPA 70% v/v swab applied sequentially, Aqueous CHG 4% w/v applied according to mfr's directions
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Oligozoospermia
A Study to Evaluate the Safety and Tolerability of Single and Multiple Dose of STSP-0902 in Healthy Subjects
This is a Phase 1b, randomized, double-blind, placebo-controlled, single and multiple ascending dose (MAD) study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of STSP-0902
- Trial name
- NCT06948799
- Testing
- STSP-0902 injection
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Staidson (Beijing) Biopharmaceuticals Co., Ltd
Spermatogenesis and Semen Disorders, Infertility, Male
Power Prenatal Supplements for Sperm Quality
Male factor infertility is a leading cause of primary and secondary infertility. Poor sperm quality is defined as having an abnormal semen analysis [WHO 2020 - https://www.who.int/publications/i/item/9789240030787].
- Trial name
- NCT05410782
- Testing
- Power Prenatal for Sperm
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Bird and Be Co Inc