Clinical trials: Infertility/Sterility, open to volunteers
Assisted Reproductive Technology, Female Infertility
A Comparing Study Between SJ04 and Ovidrel® in Healthy Subjects
This is a single-centre, randomised, open-label, single-dose, two-cycle, double-crossover study to compare the pharmacokinetics of SJ04 and Ovidrel® in healthy female subjects.
- Trial name
- NCT06599528
- Testing
- T-R (Test-Reference drug), R-T (Reference-Test drug)
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suzhou Centergene Pharmaceuticals Co.,Ltd.
Infertility
Satisfaction of Hysterosalpingo-Foam Sonography
To evaluate patient satisfaction following a HyFoSy examination performed as part of a fertility workup, by assessing the procedure's tolerability through a questionnaire administered immediately after the examination.
- Trial name
- Sat-HyFoSy (NCT07736859)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Female İnfertility
Mobile Health Support Before Oocyte Pick-Up in Infertile Women
This study aims to evaluate the effect of the OPUCARE system, a structured mobile health application used before oocyte pick-up (OPU), on medication adherence and quality of life in infertile women.
- Trial name
- OPUCARE (NCT07690969)
- Testing
- OPUCARE, Routine clinical care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Pregnancy, Pelvic Floor Dysfunction
Female Reproductive Health in Canadian Armed Forces
This is a mixed-method study aimed at gathering new evidence on reproductive health among female service members in the Canadian Armed Forces (CAF).
- Conditions
- Pregnancy, Pelvic Floor Dysfunction, Military Personnel, Contraception
- Trial name
- BEARH2025 (NCT07524764)
- Where
- Canada
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Anabolic Steroid Overdose, Infertility
Prospective, Longitudinal Study on FItness DOping in DenmarK
The aim of this prospective longitudinal study is to investigate the risks associated with use of anabolic steroids in fitness circles in Denmark in order to assess the scope of therapeutic need existing as a consequence of use.
- Conditions
- Anabolic Steroid Overdose, Infertility, Cardiovascular Complication, Illicit Drug Use
- Trial name
- FIDO-DK/RH (NCT05599438)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Caroline Michaela Kistorp
Azoospermia, Nonobstructive, Teratospermia
Study of Tolerability, Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Medicinal Product MediReg®
The study is open to patients with severe forms of male infertility (non-obstructive disorders of spermatogenesis, including azoospermia).
- Conditions
- Azoospermia, Nonobstructive, Teratospermia, Oligospermia, Men Infertility
- Trial name
- MARS (NCT06869863)
- Testing
- Medicinal product MediReg® (Human Mesenchymal Stromal Cell Secretome), lyophilizate for preparation of solution for injection in patients with severe spermatogenesis disorders, Clostilbegit (clomiphene) 50 mg 1 tablet x 1 p a day - 3 months, Triovit - 1 tablet x 1 p a day - 3 months, Folic acid - 1 tablet x 1 p a day - 3 months.
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Lomonosov Moscow State University Medical Research and Educational Center
Atypical Endometrial Hyperplasia, Fertility Issues
Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia
To investigate the efficacy of weight management plus levonorgestrel intrauterine system (LNG-IUS) or megestrol acetate (MA) in obese patients with endometrial atypical hyperplasia (EAH) asking for conservative therapy.
- Conditions
- Atypical Endometrial Hyperplasia, Fertility Issues, Overweight and Obesity
- Trial name
- NCT05316493
- Testing
- Intensive Lifestyle Intervention (ILI), Megestrol Acetate 160 MG Oral Tablet, Levonorgestrel-Releasing Intrauterine Contraceptive System (Mirena), 52 Mg
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Xiaojun Chen
Infertility, Female, Mayer Rokitansky Kuster Hauser Syndrome
Uterus Transplantation From a Multi-organ Donor
Uterus transplantation: screening, in vitro fertilization [IVF] treatment to be able to freeze embryos, uterus transplantation, pregnancy and afterwards removal of the uterus.
- Trial name
- NCT03252795
- Testing
- uterus transplantation
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Fertility Issues, Emotional Stress
Frame Support Study
This is a randomized, controlled pilot study evaluating an intervention of non-significant risk. Potential subjects will be women who have completed an initial new patient consultation at one of the participating fertility…
- Trial name
- NCT07083700
- Testing
- Frame Access
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Inception Fertility Research Institute, LLC
Infertility, Female
Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in Women With Primary Infertility
We aim to assess the Safety and Efficacy of Cervical Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in women with primary infertility
- Trial name
- NCT06769204
- Testing
- EMLA SPRAY
- Volunteers
- 90 people
- Sponsor
- Cairo University
IVF Patients, Female Infertility
Endometrial Immune Profile Changes After Autologous Intrauterine PRP Treatment
The success rate after treatment by in-vitro fertilisation (IVF) strongly depends on the endometrial receptivity, which in turn is strictly connected to the endometrial immune profile.
- Trial name
- NCT07535190
- Testing
- Platelet rich plasma (PRP)
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Nadezhda Women's Health Hospital
Infertility, Mental Health
Patient Empowerment Project (PEP) Study
The Patient Empowerment Project (PEP) will be integrated into the intake process at a fertility clinic to prepare clinical staff for any patient sensitivities or preferences and provide extra support if needed.
- Trial name
- PEP (NCT07725458)
- Testing
- Patient Empowerment Program (PEP)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Inception Fertility Research Institute, LLC
Anxiety, Stress
Aromatherapy for Mental Health Promotion in IVF Patients
The experience of infertility can cause significant emotional instability, especially for patients awaiting In Vitro Fertilization (IVF) treatment, generating anxiety, stress, and depressive symptoms.
- Conditions
- Anxiety, Stress, Depression Disorder, Quality of Life
- Trial name
- NCT07480668
- Testing
- Lavender essential oil Inhalation, Synthetic lavender aroma inhalation
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Federal University of Minas Gerais
Varicocele, Male Infertility
Effect of Varicocelectomy on Spermatogenic Cell Count and Semen Parameters
This study aims to evaluate how varicocele surgery (varicocelectomy) affects the number of immature sperm cells (spermatogenic cells) found in the semen of infertile men.
- Conditions
- Varicocele, Male Infertility, Infertility, Varicocelectomy
- Trial name
- NCT07684963
- Testing
- Subinguinal Microsurgical Varicocelectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Intrauterine Adhesions
hBMSC Uterine Artery Infusion for Severe IUA-Related Infertility
The goal of this clinical trial is to test a new approach: delivering human bone marrow mesenchymal stem cells (hBMSCs) via the uterine artery to treat infertility caused by severe intrauterine adhesions (IUA).
- Trial name
- NCT07176143
- Testing
- Delivering human bone marrow mesenchymal stem cells via the uterine artery
- Volunteers
- 60 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Fertility Issues
Testicular Tissue Cryopreservation (TTC)
The "Testicular Tissue Cryopreservation" study is open to a subset of patients facing disease or treatment regimens that could lead to infertility (gonadotoxic therapies).
- Trial name
- TTC (NCT06387498)
- Testing
- Testicular tissue biopsy and cryopreservation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
IVF, Infertility
What To-be-discard Biomaterials From ART Cycles Can Tell us About the Treatment Cycle Outcome?
Various to-be-discard material from IVF treatment cycle will be collect and examined, aiming to identify potential reasons of successful outcome or cycle failure.
- Trial name
- NCT06021340
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Infertility, Embryos Transfert
Plasma Relaxin Measurement Based on Endometrial Preparation for Embryo Transfer
Pregnancies achieved through assisted reproductive technology (ART) are associated with more obstetric complications than natural pregnancies.
- Trial name
- TEC-RELAX (NCT07477340)
- Testing
- Relaxine dosage
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Infertility
Investigating Micro-Manipulation Procedures for Assisted Hatching Timing
This study aims to assess the clinical significance of cleavage stage (Day 3) assisted hatching compared to assisted hatching at the blastocyst stage (Day 5,6,7) of embryo development at the time of trophectoderm (TE) biopsy for…
- Trial name
- IMPACT (NCT06377917)
- Testing
- Laser Assisted Hatching
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
PCOS (Polycystic Ovary Syndrome), Infertility
Letrozole Extended vs Traditional Therapy for Ovulation Induction in Women With PCOS (PROLEx-PCOS)
This randomized clinical trial aims to compare the efficacy and safety of extended letrozole therapy (5 mg/day for 10 days) versus standard letrozole therapy (5 mg/day for 5 days) for ovulation induction in women with polycystic…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Infertility, Anovulation
- Trial name
- PROLEx-PCOS (NCT07159880)
- Testing
- Traditional Letrozole Therapy, Extended Letrozole Therapy
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GABRIEL MONTEIRO PINHEIRO