Clinical trials: Infertility, completed
Anesthesia, Local
A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution
This is a Phase 3, randomized, placebo-controlled, double masked, parallel design study in healthy subjects performed in the US.
- Trial name
- NCT04513652
- Testing
- AG-920
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Infertility
Access to Infertility Services: Clinic Perspective
Since the identification of the human immunodeficiency virus (HIV) and the acquired immunodeficiency syndrome (AIDS) in the 1980s, there have been significant advances made in the management and long-term prognosis for infected…
- Trial name
- NCT00782132
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Infertility
Long Protocol and Growth Hormone in Poor Responders
The long down regulation protocol is widely used in the in vitro fertilization cycles, now it will be assessed regarding its efficacy, in poor responder females undergoing in vitro fertilization cycles, alone and after the…
- Trial name
- NCT02338206
- Testing
- Growth hormone
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Infertility, Male, Depression
Impact of Duloxetine on Male Fertility
The investigators are conducting a placebo-controlled, randomized control trial with duloxetine in healthy, fertile men not previously on any antidepressants.
- Trial name
- NCT03038867
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility, Female
Effect of Oral Sildenafil Citrate on Improvement of Endometrial Thickness
One hundred thirty women with unexplained infertility participated in a prospective clinical study. Patients were assigned at random to one of two groups.
- Trial name
- NCT05846906
- Testing
- Sildenafil Citrate, Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Healthy
Pergoveris FD and Liquid China BE Study
The main purpose of this study is to assess the bioequivalence (BE) of the fixed combination of follitropin alfa and lutropin alfa in Pergoveris freeze-dried (FD) (Test 1) or in Pergoveris Liquid (Test 2) versus the…
- Trial name
- NCT04899193
- Testing
- Pergoveris FD, Pergoveris Liquid, Gonal-f
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Self Efficacy
Learning From Online Video Education for Controlled Ovarian Stimulation
The Learning from Online Video Education (LOVE) study seeks to determine if online instructional videos on how to administer medication needed for in vitro fertilization (IVF) help improve the quality of life and reduce stress…
- Trial name
- LOVE (NCT02979990)
- Testing
- Instructional Video, Control Video
- Where
- United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility
Evaluation of the Impact of Reduced Oxygen Concentration on Embryonic Development
During this study, patients will undergo a routine in vitro fertilization cycle as they would otherwise if not participating in the study.
- Trial name
- LO2 (NCT02919384)
- Testing
- 2% oxygen concentration in the incubator
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Hand Hygiene
Hand Hygiene Before Non-sterile Glove Use
The importance of healthcare worker hand hygiene in decreasing bacterial transmission between patients is well documented. Healthcare workers may don non-sterile gloves in routine care of patients, particularly for those patients…
- Trial name
- NCT01571778
- Testing
- Hand Hygiene before Donning Non-sterile Gloves
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Phlebitis, Catheter Complications
Peripheral IV Dressing and Phlebitis in Patients From Amazon
Pragmatic, randomized, single-blinded, controlled clinical trial of the effect of dressing and stabilization of peripheral intravenous catheters on the occurrence of phlebitis in adult patients attended at a hospital from the…
- Trial name
- IVDRESAMAZON (NCT04569474)
- Testing
- Transparent dressing
- Where
- 2 sites in Brazil
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Female Infertility Due to Advanced Maternal Age
Mitochondrial Energy Production in ART (Assisted Reproductive Technology )
Oocyte maturation requires a lot of energy, which is provided by the mitochondria via the synthesis of ATP. The majority of patients with advanced maternal age (AMA) have poor egg quality.
- Trial name
- Mitenergy (NCT02727400)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Anovulation, Amenorrhea
Effects of Gynecological Age on LH Sensitivity to Energy Availability
The purpose of this experiment is to investigate whether the dependence of luteinizing hormone pulsatility on energy availability declines during adolescence.
- Conditions
- Anovulation, Amenorrhea, Infertility, Starvation
- Trial name
- NCT00260286
- Testing
- Energy availability
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ohio University
Polycystic Ovary Syndrome, Infertility, Female
Effect of Nitric Oxide Donors on Uterine and Subendometrial Blood Flow in Patients With Unexplained Infertility
The purpose of the study to evaluate effect of nitroglycerin trans-dermal patches on uterine and sub-endometrial blood flow in women with unexplained infertility.
- Trial name
- NCT03481582
- Testing
- Nitroglycerin, Three dimensional power doppler
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infertility Unexplained, Infertility, Male
Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
Infertility affects about 10% of all couples and is defined by a failure to achieve a clinical pregnancy within a year of regular unprotected sexual intercourse.
- Conditions
- Infertility Unexplained, Infertility, Male, DNA Damage
- Trial name
- NCT03319654
- Testing
- DNA fragmentation by TUNEL assay
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Follicular Fluid, Granulosa Cell
Intrauterine Flushing With Follicular Fluid Plus Granulosa Cells
One hundred forty patients with male factor infertility are randomized into two groups. In the study group, flushing the endometrial cavity with 2ml of clear follicular fluid with granulose cells will be performed using an IUI…
- Conditions
- Follicular Fluid, Granulosa Cell, Embryo Implantation
- Trial name
- NCT04077970
- Testing
- Intrauterine flushing of follicular fluid with granulosa cells
- Where
- Iran
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Mrk Anomaly, Infertility, Female
Uterus Transplantation LD - Feasibility Study - Sahlgrenska - BMC
Medical know-how concerning uterus transplantation will be transferred to new site by structured process involving theory, animal workshops and a clinical feasibility study on human subjects.
- Trial name
- GOT-BMC-UTx (NCT03590405)
- Testing
- uterus transplantation surgery and IVF
- Where
- 2 sites in Sweden
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Infertility
Physical Endometrial Manipulation and Its Effect on ICSI
Unexplained infertility is clinically diagnosed when there are no apparent or clear factors causing infertility on regular infertility assessment tools .
- Trial name
- NCT03345251
- Testing
- Hydrotubation
- Where
- Egypt
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Infertility
Does a Brief Intervention Decrease Patient Drop Out Rates?
The goal of this study is to determine a) if a follow-up email to selected patients who had an initial consult with an infertility specialist, but did not return for a second visit, would change return to care behavior and b) why…
- Trial name
- NCT04803045
- Testing
- Follow up email
- Where
- United States
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility, Male, IVF
BPA Levels Relationship With IVF/ICSI Outcomes in Patients With Male Factor
Association between blood and semen BPA levels and ICSI outcomes in patients with male factor
- Trial name
- NCT05224284
- Testing
- BPA levels
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Infertility
Novel Approach With Double Agent Artificial Oocyte Activation for Repeated Fertilization Failure Due to Combined Sperm and Oocyte Factor
Novel approach for Oocyte fertilization failure for difficult cases not respond to traditional methods of assisted reproduction as intracytoplasmic sperm injection.
- Trial name
- CISC (NCT02418416)
- Testing
- Oocyte double chemical activation
- Where
- 3 sites in Bahrain, Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital