Clinical trials: Infertility, completed
Fertility Issues
Continuous Double Ovarian Stimulation.
To evaluate the efficacy of the weekly use of corifollitropin alfa in double ovarian stimulation process and to compare it to the conventional protocol with daily medication administration.
- Trial name
- NCT05815719
- Testing
- Corifollitropin Alfa, Follitropin Alfa, Follitropin Alfa Biosimilar
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Infertility, Female, Reproductive Sterility
Evaluation of Salivary ELISA for Hormone Monitoring in IVF Patients
In assisted reproductive treatment (ART), it is necessary to follow closely the stimulation cycles of patients undergoing these treatments in order to monitor the number and size of developing follicles.
- Trial name
- SALIVA_MINT (NCT05184777)
- Testing
- Determination of progesterone and oestradiol
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility
Aspiration of Excessive Endometrial Fluid at the Day of Ovum Retrieval Plus Diosmin in (ICSI) Cycles
To notify the effect of aspiration of excessive endometrial fluid in addition to Diosmin in cases undergoing intracytoplasmic sperm injection (ICSI) cycles.
- Trial name
- NCT02158000
- Testing
- group A
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
Infertility, Female
hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility
To explore the therapeutic effect and safety of human umbilical cord mesenchymal stem cells on thin endometrial infertility and to explore whether human umbilical cord mesenchymal stem cells using collagen as the carrier can…
- Trial name
- NCT05495711
- Testing
- human umbilical cord mesenchymal stem cell complex collagen, intrauterine injection
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Infertility
Reduction of Sperm DNA Fragmentation by Oral Ginger
This study is a randomized, double blind, controlled clinical trials assess the efficacy of the ginger oral treatment on sperm DNA fragmentation, sperm parameters and male hormones.
- Trial name
- NCT02032251
- Testing
- oral administration of ginger
- Where
- Iran
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Progesterone Levels, Infertility
The Luteal Phase After GnRHa Trigger - a Proof of Concept Study
The purpose of this study is to investigate levels of progesterone in the luteal phase after various stimulations in the follicular phase and treatment with GnRH antagonist protocol followed by GnRHagonist as induction of…
- Trial name
- NCT01504139
- Testing
- hCG(r-hCG, Ovitrelle, Merck-Serono, Hellerup, Denmark) in the late follicular phase + luteal phase, hCG(r-hCG, Ovitrelle,Merck-Serono, Hellerup, Denmark) in the follicular phase + luteal phase, LH(r-LH,Luveris, Merck-Serono, Hellerup, Denmark) in the luteal phase
- Where
- Denmark
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Infertility
Effectiveness of Estradiol Valerate Pretreatment in Antagonist Protocol for Poor Ovarian Response Patient
The purpose of study is to assess the efficacy of add-on estrogen pretreatment in GnRH antagonist protocol on oocyte retrieval as compared with GnRH antagonist protocol for patients with poor ovarian response Add-on estrogen…
- Trial name
- NCT03300518
- Testing
- Follitropin Beta;MSD, Ganirelix, hCG
- Where
- China
- Volunteers
- 552 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Subfertility
Corifollitropin Alfa Compared to Daily rFSH in Poor Responders Undergoing ICSI
Corifollitropin alfa has been shown to result in significantly more oocytes compared to daily recombinant follicle stimulating hormone (recFSH) (Devroey et al., 2009), probably due to the higher circulating FSH activity during…
- Trial name
- NCT02046655
- Testing
- Corifollitropin alfa, rFSH
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Aristotle University Of Thessaloniki
Primary Ovarian Insufficiency, Low Ovarian Reserve
Rejuvenation of Premature Ovarian Failure With Stem Cells
The ROSE-1 study is designed to determine the efficacy of bone marrow derived stem cell therapy on ovarian function recovery in subjects with idiopathic and other types of premature or primary ovarian failure (POF or POI) and low…
- Conditions
- Primary Ovarian Insufficiency, Low Ovarian Reserve, Premature Ovarian Failure
- Trial name
- ROSE-1 (NCT02696889)
- Testing
- ROSE-1 Protocol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Illinois at Chicago
Infertility
Three-dimensional Versus Two-dimensional Ultrasound Guided Embryo Transfer in Women Undergoing ART Treatment
Objectives: To assess whether embryo transfer guided by three-dimensional ultrasound (3DUS) produces a significantly higher clinical pregnancy rate than embryo transfer guided by two-dimensional ultrasound (2DUS).
- Trial name
- NCT02413697
- Testing
- Two-dimensional ultrasound, Three-dimensional ultrasound
- Where
- Hong Kong
- Volunteers
- 481 people
- Sponsor
- Chinese University of Hong Kong
Infertility, Female
CAPA-IVM Versus STANDARD IVM
The aim of this study is to evaluate the effectiveness and safety of CAPA-IVM versus standard IVM in women with polycystic ovarian morphology (PCOM) or polycystic ovary syndrome (PCOS) .
- Trial name
- NCT03921710
- Testing
- CAPA-IVM, Standard-IVM
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Mỹ Đức Hospital
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital
Infertility
The Exogenous Progesterone Free Luteal Phase After GnRHa Trigger - a Pilot Study in Normo-responder IVF Patients
After hCG trigger a large amount of exogenous progesterone is used for luteal phase support in many countries until 10th week of gestation.
- Trial name
- GnRHa trigger (NCT01980680)
- Testing
- hCG, Progesterone and Estradiol
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Peter Humaidan
Infertility, Female, Pain, Postoperative
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
In this research study we want to learn more about how effective certain medications are at reducing pain after oocyte (egg) retrieval surgery and how effective they are at reducing the time between the retrieval and discharge…
- Trial name
- NCT03073980
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Infertility, Preimplantation Genetic Screening
Cumulative Live Birth Rates in Patients With Repeated Implantation Failure (RIF) Undergoing Preimplantation Genetic Screening (PGS )
This is a single centre retrospective study in repeated implantation failure patients: < 39 years old, at least 4 D3 good quality embryos or 2 good quality blastocysts transferred without implantation, absence of known causes of…
- Trial name
- NCT03001648
- Testing
- PGS (Preimplantation Genetic Screening) with trophectoderm biopsy
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundacion Dexeus
Infertility Assisted Reproductive Technology, Oocyte Retrieval
ART Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved
This is a monocentric retrospective observational study. The study focuses on the women who underwent Assisted Reproductive Technology (ART) cycles with poor ovarian response (POR), defined as <4 oocytes retrieved.
- Trial name
- POR (NCT06950476)
- Testing
- Oocyte Retrieval
- Volunteers
- 3,761 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Infertility, Infertility, Female
Follicular Fluid Fetuins in in Vitro Fertilization
This study aims to investigate whether follicular fluid concentrations of fetuin A and fetuin B are associated with the clinical pregnancy and live birth rates in in vitro fertilization (IVF) cycles.Twenty-nine women with poor…
- Trial name
- NCT04201847
- Testing
- Serum test
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Samsun Education and Research Hospital
Infertility
Ovarian Stem Cells From Women With Ovarian Insufficiency
Background: Primary ovarian insufficiency (POI) is a condition that affects ovary function. It means that the ovaries are not able to function at a level appropriate for a woman's age.
- Trial name
- NCT01702935
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility
Supplementing Intracytoplasmic Sperm Injection Handling Medium With Chaetoglobosin A ( ICSI-CA)
Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc.
- Trial name
- NCT03678584
- Testing
- Medium Supplemented with Chaetoglobosin A
- Where
- 3 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Ibn Sina Hospital
Infertility, Male
The Effect of a Multimodal Lifestyle Program on Male Fertility
A non-pharmacological study, which examines the effect of lifestyle intervention on sperm quality among men in fertility treatment.
- Trial name
- NCT04761250
- Testing
- Lifestyle
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan