Clinical trials: Infertility, completed
Infertility, Female
Safety and Efficacy of Sonohysterosalpingography for the Evaluation of Infertility
This pilot study is a collaborative effort between Northwell Health's Departments of Fertility and Radiology.The aim of this study is to evaluate the feasibility of the Sonohysterosalpingography (sonoHSG) for it to be determined…
- Trial name
- NCT03234569
- Testing
- sonoHSG
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Infertility, Female, Endometriosis
Predicting Endometrial Receptivity for Optimal Reproductive Management
The purpose of this study is to understand why some women are infertile (unable to conceive a child). The investigators hope to learn if an endometrial biopsy after egg retrieval is feasible for detecting biomarkers for…
- Trial name
- PERFORM (NCT04107129)
- Testing
- Endometrial Biopsy, Euploid embryo transfer, Blood sample
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Stanford University
Infertility
IS Three d Power Doppler of the Endometrial and Subendometrial Regions Effective in Predicting Endometrial Implantation?
Three D power Doppler US was done for every woman at the day after HCG administration. Ovum pick up was done after 35 hours following HCG administration.
- Trial name
- NCT04081870
- Testing
- 3D power doppler US
- Volunteers
- 120 people
- Sponsor
- Benha University
Female Infertility
Study of the Cleavage of the Egg in Relation to the Stimulation Treatment
This post-marketing, single-center prospective study will be conducted in an open-label, non-interventional setting, for women seeking fertility treatment and will describe cleavage dynamics in relation to the age of the oocyte…
- Trial name
- NCT01674894
- Where
- Denmark
- Volunteers
- 356 people
- Sponsor
- Ferring Pharmaceuticals
Anesthesia, Local
A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric Population
A Phase 3, randomized, active-controlled, study in pediatric subjects. It is designed to evaluate the safety and anesthetic efficacy of one dose of AG-920 ophthalmic solution compared to Proparacaine Hydrochloride Ophthalmic…
- Trial name
- NCT05325853
- Testing
- AG-920, Proparacaine Ophthalmic
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Endometrial Polyps in Infertile Patients
Misoprostol as a Treatment for Endometrial Polyps in Infertile Patients
Endometrial polyps are one of the main causes of infertility in women. In this work we propose an alternative, effective, economical and safe treatment: the use of misoprostol
- Trial name
- NCT04270994
- Testing
- Misoprostol
- Volunteers
- 54 people
- Sponsor
- Henry Aristoteles Mate-Sánez
Infertility
An Observational Study to Evaluate Efficacy, Safety and Clinical Outcomes of Currently Used Pharmaceutical Therapies for Controlled Ovarian Stimulation in Assisted Reproductive Techniques
Human gonadotrophins have been successfully used for the treatment of infertility for more than 30 years. This observational study is being conducted to evaluate the efficacy and safety of the gonadotropins used for controlled…
- Trial name
- ESCORT (NCT01149070)
- Where
- Hungary
- Volunteers
- 10,103 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
Incidence of Non Receptive Endometrium in Obese Women
This study evaluates the incidence of Non Receptive endometrium in obese infertile women compared to infertile normal weight women using Endometrial Receptivity Array (ERA) test, containing 238 genes, identifying the receptivity…
- Trial name
- NCT02205866
- Testing
- Endometrial Receptivity Array analysis of endometrial biopsy
- Where
- 3 sites in United States, Spain
- Volunteers
- 183 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility
A Non-inferiority Trial on Pain Relief During Oocyte Retrieval
The objective of the trial is to compare fentanyl and midazolam vs diazepam and pethidine in terms of the pain levels and post-operative side effects of TUGOR
- Trial name
- NCT02494180
- Testing
- fentanyl, pethidine, Diazepam
- Volunteers
- 170 people
- Sponsor
- Kwong Wah Hospital
Intracytoplasmic Sperm Injection, Infertility, Male
Outcome of Using Sperm Bound to the Zona Pellucida of Immature Oocytes for Intracytoplasmic Sperm Injection (ICSI)
In vivo, the zona pellucida (ZP) of the oocyte can bind to normally functional sperm. The ZP-sperm interaction is one of the final steps of natural selection during their journey in the female reproductive tract.
- Trial name
- NCT05724979
- Testing
- ZP-binding
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Infertility
Efficacy of Embryo Transfer Procedure Guided by Transvaginal Ultrasound Versus Abdominal Ultrasound in Oocytes Recipients
The objective of this study is to evaluate the efficacy of embryo transfer procedure guided by transvaginal ultrasound versus abdominal ultrasound in recipients of oocytes as well as the advantages and disadvantages of the new…
- Trial name
- NCT01137461
- Testing
- ultrasound-guided embryo transfer
- Where
- Spain
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
Infertility, Female
Effects of Wurn Technique on Dyspareunia, Menstrual Cramps & QoL in Infertile Women
Wurn technique is a PT technique. It is site specific massage therapy in the form of relaxing technique, helps to promote the function of abdominopelvic and reproductive organs.
- Trial name
- NCT06845670
- Testing
- Wurn technique
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Endocrine Disease, Infertility
Hormonal Regulation of Puberty and Fertility
Background: The body produces gonadotropin-releasing hormone (GnRH) about every 2 hours. GnRH travels through the bloodstream to the pituitary gland, where it stimulates the gland to produce hormones called gonadotropins.
- Conditions
- Endocrine Disease, Infertility, Hypogonadism, Amenorrhea
- Trial name
- NCT01511588
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infertility
C Terminal Variants of FSH Receptor
Follicle-stimulating hormone (FSH) is used in medically assisted procreation, to induce an ovarian stimulation in women. However, the FSH dose that has to be injected is quite hard to adjust, because an excess of exogenous…
- Trial name
- NCT01524588
- Where
- France
- Volunteers
- 814 people
- Sponsor
- University Hospital, Tours
Oligospermia
Is Oxidative Stress in Semen Reduced by Lifestyle Intervention
In this study we aim to investigate whether a 3-month life-style intervention would reduce oxidative stress (OS) in semen in men of infertile couples attending IVF-treatment.
- Trial name
- NCT03898752
- Testing
- Omega 3
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Peter Humaidan
Polycystic Ovary Syndrome
PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene
1. Metformin increases the pregnancy rate when added to the standard treatment of anovulatory polycystic ovary syndrome (PCOS). 2.
- Trial name
- PCOSMIC (NCT00795808)
- Testing
- Metformin, Metformin + Clomiphene, Clomiphene
- Where
- New Zealand
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Infertility
Study of Free DNA Content of Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment
Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in intra cytoplasmic sperm injection Treatment Cycles.
- Trial name
- NCT02480491
- Testing
- measuring cell freeDNA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sadat City University
Infertility
Use of GM-CSF Supplemented IVF Medium in Patients With Recurrent Implantation Failure
The purpose of this study is to determine whether in Assisted Reproductive Technologies the use of culture medium supplemented with GM-CSF, a growth factor working on stem cells, may improve the embryo implantation in patients…
- Trial name
- NCT01718210
- Testing
- GM-CSF medium, CONTROL
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Infertility
Early Luteal Progesterone Profile After hCG Triggering
This pilot-study will help characterize the serum progesterone profiles in IVF patients and correlate progesterone levels to ovarian follicles obtained after stimulation with exogenous gonadotropins.
- Trial name
- NCT02798146
- Testing
- blood collection
- Volunteers
- 20 people
- Sponsor
- Vietnam National University
Infertility, Female
Cabergoline Before or After Oocyte Collection for Follicular Resolution
Randomized trial comparing the efficacy of two different times of administration of cabergoline in patients undergoing controlled ovarian stimulation and oocyte collection.
- Trial name
- NCT04096027
- Testing
- Cabergoline Pill
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas