Clinical trials: Infertility
Infertility
Genetic Epidemiology of Ovarian Aging
The purpose of this study is to identify clinical and genetic markers of ovarian aging. In this process, we will evaluate environmental factors that may affect fertility and the age at which fertility declines, and may influence…
- Trial name
- NCT00501800
- Where
- United States
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility, Infertility, Female
Developmental Epidemiological Study of Children Born Through Reproductive Technology
DESCRT will be a long-term study that both looks back in time, at successful pregnancies, and forward in time at early pregnancy and long-term as these children grow.
- Conditions
- Infertility, Infertility, Female, Infertility, Male, Infertility Primary
- Trial name
- DESCRT (NCT03799107)
- Where
- United States
- Volunteers
- 2,020 people
- Sponsor
- University of California, San Francisco
Infertility, Cardiovascular Risk Factor
The Longitudinal Evaluation of Ovarian Aging and Cardiovascular Risk
Despite significant improvements in prevention and treatment of cardiovascular disease (CVD), the growing aging population suggests CVD will continue to pose a significant public health burden.
- Trial name
- OVACV (NCT03825120)
- Where
- United States
- Volunteers
- 865 people
- Sponsor
- University of California, San Francisco
Infertility, Infertility Secondary
Sperm Preparation Prior to Intrauterine Insemination Study
This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.
- Conditions
- Infertility, Infertility Secondary, Infertility Unexplained, Anovulation
- Trial name
- PIoUS (NCT05693220)
- Testing
- Zymot Multi sperm separation device, Density gradient centrifugation
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of California, San Francisco
Infertility
Group Preconception Care for Fertility Patients
Group Preconception Care for Fertility Patients aims to translate the well-established group prenatal care model to preconception care to improve pregnancy and neonatal outcomes.
- Trial name
- NCT05924464
- Testing
- Group Preconception Care
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Pennsylvania
Infertility, Female
Impact of a Web-Based Mind-Body Awareness Program on Women Undergoing Infertility Treatment
The goal of this two-group parallel randomized controlled study is to determine the effect of a web-based mind-body-based awareness program based on Meleis Transition Theory on fertility awareness and readiness levels in women…
- Trial name
- NCT06585137
- Testing
- Web-Based Mind-Body Based Awareness Program
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Hacettepe University
Infertility
Virtual Reality for Pain and Anxiety During HyFoSy
This randomized controlled study will evaluate whether virtual reality (VR) reduces procedural pain and anxiety in women undergoing hysterosalpingo-foam sonography (HyFoSy), a minimally invasive ultrasound-based procedure used to…
- Trial name
- NCT07816393
- Testing
- virtual reality, rest
- Where
- Israel
- Volunteers
- 68 people
- Sponsor
- HaEmek Medical Center, Israel
Infertility; In Vitro Fertilization; Embryo Development
Day-3 vs Day-5 Assisted Hatching: Impact on Blastocyst Morphology and PGT-A Outcomes
This randomized controlled trial compared assisted hatching (AH) performed on Day 3 versus Day 5 in patients undergoing IVF-ICSI with preimplantation genetic testing for aneuploidy (PGT-A).
- Trial name
- AH-PGTA (NCT07154875)
- Testing
- Laser-Assisted Hatching
- Where
- Vietnam
- Volunteers
- 141 people
- Sponsor
- Hoang Minh Ngan
Aging, Epigenetic Aging
Human Sperm Cryopreservation as an Alternative to the Decline of Sperm Quality With Aging
This observational study will evaluate whether sperm cryopreservation can help preserve sperm quality and molecular characteristics that may be affected by increasing paternal age.
- Conditions
- Aging, Epigenetic Aging, Infertility, Assisted Reproduction Technologies
- Trial name
- NCT07814235
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IVI Murcia
Infertility Counseling, Communication Skills
AI-Powered OSCE Coaching in Improving Infertility Counseling Skills in Nursing Students
This randomized controlled experimental study aims to evaluate the effectiveness of a generative artificial intelligence-based "OSCE Coach" in improving infertility counseling communication and empathy skills among nursing…
- Trial name
- AI-OSCE-Infert (NCT07404020)
- Testing
- AI-Powered OSCE Coaching
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Sakarya University
Infertility
Progesterone Supplementation After Letrozole-stimulated Insemination
This trial aims to investigate whether luteal phase support improves the chance of pregnancy in women undergoing intrauterine insemination (IUI) following ovarian stimulation with letrozole.
- Trial name
- LIFT (NCT07508657)
- Testing
- Progesterone
- Where
- 4 sites in Denmark
- Volunteers
- 690 people
- Sponsor
- Kirstine Kirkegaard
Infertility
Hormone-free Antral Retrieval for Viable Embryo Storage & Transfer
This study is testing whether eggs can be collected from small follicles without using the usual ovarian stimulation medications. Participants will have up to three egg retrieval procedures.
- Trial name
- HARVEST (NCT07801105)
- Testing
- CAPA-IVM System, Serial Unstimulated Transvaginal Oocyte Retrieval, ICSI, Blastocyst Culture, PGT-A, Embryo Vitrification/Accumulation, and Single Euploid Embryo Transfer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kevin Doody
Infertility, Female, Sexual Intercourse
Sex or no Sex: That is the Question.
This study aims to evaluate the impact of sexual intercourse and orgasm in the 72 hrs following embryo transfer of blastocysts on the clinical pregnancy rate.
- Trial name
- NCT04880590
- Testing
- Sex intercourse
- Where
- Spain
- Volunteers
- 412 people
- Sponsor
- Fundación Santiago Dexeus Font
Polycystic Ovary Syndrome, Infertility, Female
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
A Prospective, Multicenter, Randomized, Pivotal Study of the May Health System in Transvaginal Ablation of Ovarian Tissue under Ultrasound Guidance in Women with Infertility due to Polycystic Ovary Syndrome
- Trial name
- NCT06206746
- Testing
- May Health System
- Where
- 19 sites in United States
- Volunteers
- 93 people
- Sponsor
- May Health
Infertility, Female
One-shot Ovarian Stimulation Protocol (One-shot)
The current prospective observational pilot study aims to evaluate the endocrine profile of a single-injection protocol (single CFA + daily oral administration of CC).
- Trial name
- One-shot (NCT06635538)
- Testing
- Corifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1, Clomiphene Citrate (CC) 100 mg/day from D1, Monitoring cycle
- Where
- 3 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Fundación Santiago Dexeus Font
Infertility
A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA)
The purpose of this study is to assess the efficacy and safety of follitropin alfa/lutropin alfa in Japanese participants with Luteinizing hormone (LH) and Follicle stimulating hormone (FSH) deficiency undergoing Assisted…
- Trial name
- NCT07340827
- Testing
- Follitropin alfa/lutropin alfa (MBJ-0011), hMG, Cetrorelix acetate
- Where
- 21 sites in Japan
- Volunteers
- 266 people
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Multidimensional Tubal Function Assessment and Individualized Treatment Strategies for Tubal Factor Infertility
Comprehensive Assessment System for Fallopian Tube Function and Clinical Study on Individualized Treatment Strategies
This clinical study aims to develop a comprehensive system to evaluate tubal function and to optimize individualized treatment strategies for patients with tubal factor infertility (caused by hydrosalpinx, obstruction, or…
- Trial name
- NCT07808229
- Testing
- Optimize the techniques and plans for fallopian tube reconstruction surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University People's Hospital
Male Infertility
Home Semen Testing in Men Beginning Attempts to Conceive
The overall objective of the proposed study is to enhance early detection of male factor infertility and reduce cost and morbidity associated with delayed diagnosis through development of a universal screening model based on home…
- Trial name
- NCT05503862
- Testing
- YoSperm
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Northwestern University
Infertility
REKOVELLE PEN for S.C. Injection General Drug Use Survey (Controlled Ovarian Stimulation in Assisted Reproductive Technologies)
This survey targets controlled ovarian stimulation with this drug for the development of multiple oocytes in women undergoing assisted reproduction (ART) such as in vitro fertilization (IVF) or intracytoplasmic sperm injection…
- Trial name
- NCT06545877
- Where
- Japan
- Volunteers
- 571 people
- Sponsor
- Ferring Pharmaceuticals
Infertility, Ovulation Induction
Follitropin Delta Versus Follitropin Alfa in Indonesian Women Undergoing IUI
The goal of this retrospective observational study is to compare two types of follicle-stimulating hormone, follitropin delta and follitropin alfa, used for ovarian stimulation in Indonesian women undergoing intrauterine…
- Conditions
- Infertility, Ovulation Induction, Insemination, Artificial
- Trial name
- NCT07801781
- Testing
- Follitropin Delta, Recombinant, Follitropin Alfa (GONAL-F)
- Where
- Indonesia
- Volunteers
- 228 people
- Sponsor
- Stella Maris Women and Children Hospital