Clinical trials: Infertility (IVF Patients)
POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology
Impact of Day 2 Versus Day 3 Fresh Embryo Transfer on Live Birth Rate in Poor-Prognosis Patients
This study aimed to compare the efficacy (live birth rate) of fresh embryo transfer on Day 2 versus Day 3 in POSEIDON Group 4 patients, and to determine the optimal timing of embryo transfer for this population.
- Conditions
- POSEIDON Category 4, Low Prognosis in Assisted Reproductive Technology, Female Infertility Due to Diminished Ovarian Reserve
- Trial name
- NCT07533695
- Testing
- Day 2 Fresh Embryo Transfer
- Volunteers
- 470 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Infertility (IVF Patients)
Triggering Ovulation in Normo-responders Using a Modified Dual Trigger Protocol or HCG Trigger
The aim of this randomized controlled study is to compare the efficacy of a modified dual trigger protocol [a single bolos of HCG combined with two successive doses of a GnRH agonist ] with HCG [a single bolos administered 36…
- Trial name
- NCT07569302
- Testing
- Modified dual trigger, HCG
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Bedaya Hospital
Infertility, Female
The Impact of Body Mass Index on the Endometrial Microbiome in IVF Treatments. Tampere Infertility Microbiome Project (TIMP).
This study project is an observational trial involving 90 patients suffering from male type infertility. The patients are divided in two groups (45 patients per group) based on their body mass index (BMI).
- Trial name
- NCT04168567
- Testing
- Microbiome analysis
- Where
- Finland
- Volunteers
- 91 people
- Sponsor
- Tampere University Hospital
Infertility
Addition of Prednisolone and Heparin in Patients Undergoing IVF With Failed IVF Cycles
The addition of heparin and prednisolone increases pregnancy outcome parameters in women undergoing In Vitro Fertilisation (IVF) with failed IVF cycles.
- Trial name
- NCT01590173
- Testing
- Prednisolone and Heparin during COH for IVF, COH for IVF
- Where
- Greece
- Volunteers
- 86 people
- Sponsor
- National and Kapodistrian University of Athens
Infertility, Preimplantation Genetic Screening
Investigating the Cryopreserved Blastocyst's ImplantatiOn Potential After Genetic Screening
This is a two-arm parallel group randomized controlled trial at the Department of Reproductive Medicine at Ghent University Hospital.
- Trial name
- BIOPS (NCT03173885)
- Testing
- Preimplantation Genetic Screening
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University Hospital, Ghent
Infertility, Obesity
Physical Activity and ARTs
Obese women experience increased infertility rate and longer time to conception showing lower pregnancy and live-birth rates both in natural and assisted conceptions.
- Conditions
- Infertility, Obesity, Stable BMI
- Trial name
- SETART (NCT01892111)
- Testing
- Structured exercise program.
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Modena and Reggio Emilia
Infertility (IVF Patients)
The Role of hCG in Thawed Embryo Transfer
This prospective randomized trial will assess the relevance, if any, of a corpus luteum induced by hCG in transfers of thawed embryos.
- Trial name
- NCT07004192
- Testing
- HCG injection, No intervention
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Infertility, Female Infertility, Male Infertility
Severe LH Suppressed Patients After Administration of a GnRH Antagonist
The ideal stimulation protocol for ovarian stimulation is under constant debate, as we gain more pharmacological control over the patient hormonal milieu. Specifically, the debate focuses around the ideal LH levels.
- Trial name
- OPTOMALH (NCT01936077)
- Testing
- Recombinant LH (Luveris)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assuta Hospital Systems
Endometriosis, Infertility
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the…
- Trial name
- IntegrinIVF (NCT00621179)
- Testing
- Leuprolide acetate in depot suspension, No intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Colorado Center for Reproductive Medicine
Endometriosis, Infertility
The Effect of Pre-treatment With GnRH Analogues Prior in Vitro Fertilization in Patients With Endometriosis
The purpose of this study is to determine whether the administration of an analogue of gonadotropin-releasing hormone (GnRH) during the three months prior to the performing of an IVF may improve the response to ovarian…
- Trial name
- ENDOFIV (NCT01581359)
- Testing
- Triptorelin acetate
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Infertility
Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients
A prospective, randomized, controlled study to explore the efficacy and safety of using either corifollitropin alfa 150 mcg or daily recombinant follicle stimulation hormone (FSH) 300 international unit (IU) for the stimulation…
- Trial name
- NCT02466204
- Testing
- corifollitropin alfa, Follitropin Beta
- Where
- 2 sites in Vietnam
- Volunteers
- 400 people
- Sponsor
- Vietnam National University
Reproductive Sterility
Prednisolone Improves IVF Outcomes in Men With Anti-sperm Antibodies
Corticosteroids have been indicated to treat men with ASAs. Although many studies have confirmed the clinical therapeutic significance of corticosteroids in the treatment of men with ASAs, other studies have not found a…
- Trial name
- NCT02935738
- Testing
- Prednisolone treatment
- Volunteers
- 241 people
- Sponsor
- Barz IVF Center for Infertility Treatment and Embryo Research
Infertility
Platelet-Rich Protein and the Endometrium
Platelet-rich plasma (PRP) may promote the endometrial growth and improve pregnancy outcome of patients with thin endometrium undergoing ART treatments.
- Trial name
- NCT02973555
- Testing
- PRP injection
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Infertility
Autologous Mitochondrial Transfer in ICSI to Improve Oocyte and Embryo Quality in IVF Patients. Pilot Study
The principle objective is to improve embryo quality through autologous micro-injection of mitochondria isolated from Ovarian stem cells into the oocytes themselves, as a complementary ICSI technique in patients with low embryo…
- Trial name
- NCT02586298
- Testing
- Autologous mitochondria with ICSI, STANDARD ICSI PROCEDURE
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility
Endometrial Sampling (Pipelle)in IVF Patients
A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle.
- Trial name
- NCT00411021
- Testing
- Pipelle (Endometrial Sampling)
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility, Female, Anxiety
Multifaceted Benefits of Auricular Point Sticking for IVF Patients: Psychological Well-being, Sleep, and Treatment Outcomes
The goal of this clinical trial is to evaluate whether the complementary intervention of auricular point sticking therapy (APST) can improve pregnancy outcomes by ameliorating psychological distress and sleep quality in female…
- Conditions
- Infertility, Female, Anxiety, Assisted Reproductive Techniques, Dyssomnias
- Trial name
- NCT07409792
- Testing
- auricular point sticking therapy, Conventional Artificial Cycle Therapy
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University
Obesity, PCOS
Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS Patients
The aim of this study was to evaluate the impact of short-term weight reduction achieved with 12-week intervention with metformin alone or in combination with liraglutide on oocyte maturity and embryo quality in infertile obese…
- Trial name
- NCT03034941
- Testing
- Metformin, Liraglutide + metformin
- Where
- Slovenia
- Volunteers
- 35 people
- Sponsor
- University Medical Centre Ljubljana
In Vitro Fertilization
Corifollitropin Alfa in Participants Undergoing Repeated Controlled Ovarian Stimulation (COS) Cycles Using a Multiple Dose Gonadatropin Releasing Hormone (GnRH) Antagonist Protocol (Study 38825)(P05714)
The objective of the trial is to assess the non-immunogenicity and safety of corifollitropin alfa (also known as Org 36286, SCH 900962 and MK-8962) in participants undergoing repeated COS cycles using a multiple dose GnRH…
- Trial name
- Trust (NCT00696878)
- Testing
- Corifollitropin alfa, FSH, GnRH antagonist
- Volunteers
- 682 people
- Sponsor
- Organon and Co
Infertility
Use of Predictive Model to Assist Patients Having an Embryo Transfer After IVF
To determine in women undergoing IVF who are at high risk of multiple births (>35%), as calculated by the application of a predictive model - IVFsingleTM, if single embryo transfer will lead to both comparable clinical pregnancy…
- Trial name
- NCT02009891
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Fertility Centre
Infertility
Influence of Ethnical Differences on the Egg Cell Collected in Patients Undergoing Fertility Treatment
Investigators wants to analyze the differences considering the country of origin, ethnicity, characteristics, reproductive history and habits of participants undergoing in vitro fertilization (IVF) / intracytoplasmic sperm…
- Trial name
- NCT03927417
- Where
- United Arab Emirates
- Volunteers
- 1,117 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC