Clinical trials: Infertility (IVF Patients)
Infertility
Optimal Timing For Embryo Transfer For Low Responder Patients
Women undergoing in vitro fertilization (IVF) therapy, who are low responder and agree to enter the trial will be randomized to a study group, for whom embryo transfer will be done on the same day as oocyte aspiration and…
- Trial name
- NCT01040247
- Testing
- Embryo Transfer
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Poor Response to Ovulation Induction, Infertility, Female
Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders
Autologous platelet rich plasma (PRP) intraovarian infusion may improve ovarian response to controlled ovarian stimulation as well as the hormonal profile of poor ovarian response infertile women subjected to intracytoplasmic…
- Conditions
- Poor Response to Ovulation Induction, Infertility, Female, Ovarian Insufficiency, Ovarian Failure
- Trial name
- PRPPOR (NCT05181748)
- Testing
- Autologous platelet rich plasma
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Infertility
Prospective Sibling Oocyte Study of a New Method to Improve Embryo Development in IVF/ICSI Patients
Prospective, multi-centric, split-sample, sibling oocyte study evaluating the safety and efficacy of a new method to prepare sperm samples for IVF (in vitro fertilization) / ICSI (intracytoplasmic sperm injection) compared to…
- Trial name
- NCT05680363
- Testing
- HyperSperm, Standard Sperm Preparation
- Where
- 4 sites in Argentina
- Volunteers
- 41 people
- Sponsor
- Fecundis S.A.
Infertility, Female
Double Trigger in Patients With Low Number of Oocytes Retrieved Per Number of Preovulatory Follicles
The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the oocytes yield in…
- Trial name
- NCT04407065
- Testing
- Double trigger, HCG trigger
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Riyadh Fertility and Reproductive Health center
Infertility, Female, Premature Ovarian Failure
Second Step Protocol in Poor Ovarian Responder (POR)
Reduced ovarian reserve and the consequent poor ovarian response are very recurent in infertile patients, indeed a percentage of 10%-24% of couples addressed to infertility program may be classified as Poor Ovarian Responder…
- Conditions
- Infertility, Female, Premature Ovarian Failure, Fertility Disorders
- Trial name
- POR (NCT03480412)
- Testing
- Follicular Phase, Luteal Phase
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Infertility (IVF Patients), Artificial Intelligence (AI)
AI-Driven Model Impact on Patient Engagement in Medically Assisted Reproduction
Infertility is a globally significant medical condition, profoundly impacting individuals and couples both emotionally and physically.
- Trial name
- NCT07087171
- Testing
- Artificial intelligence-Machine learning report with accurate personalized probabilities of having a live birth rate
- Where
- Portugal
- Volunteers
- 774 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility, Female, Reproductive Sterility
Evaluation of Salivary ELISA for Hormone Monitoring in IVF Patients
In assisted reproductive treatment (ART), it is necessary to follow closely the stimulation cycles of patients undergoing these treatments in order to monitor the number and size of developing follicles.
- Trial name
- SALIVA_MINT (NCT05184777)
- Testing
- Determination of progesterone and oestradiol
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Ovulation Induction, In Vitro Fertilization (IVF)
Agonist Versus Classical HCG Trigger (Poor Responders, Normoresponders and High Responders)
Agonist triggering in controlled ovarian stimulation protocols is being used during last years (among high responder patients to avoid OHSS). Indeed, agonist triggering is more physiologic than HCG triggering.
- Conditions
- Ovulation Induction, In Vitro Fertilization (IVF), Infertility, Female, Oocytes
- Trial name
- NCT03307720
- Testing
- Gonadotropin Releasing Hormone Agonists (GNRH-A), Human chorionic gonadotropin
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Ginegorama S.L.
Infertility Assisted Reproductive Technology
The Feasibility of taVNS on Pregnancy Outcomes of Infertility Patients Undergoing IVF
To assess the feasibility of taVNS on pregnancy outcomes of infertility subjects undergoing IVF, the primary aim of this trial will focus on encompassing recruitment, compliance, and preliminary engagement outcomes.
- Trial name
- NCT06742788
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Infertility, Male
Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients
The purpose of this study is to compare semen parameters with in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) when male factor infertility patients abstain from ejaculation more than 48 hours (routine care)…
- Trial name
- NCT04206800
- Testing
- Ejaculatory abstinence less than 24 hours
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boston IVF
Infertility
Needle-Free Monitoring for IVF Patient Cycles
Salivary diagnostic testing is emerging as a less invasive, inexpensive alternative to serum analyte measurements with proven diagnostic accuracy in clinical settings.
- Trial name
- NCT03162809
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility, Female, Polycystic Ovary Syndrome
Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF
The aim of the study is to study the effect of an antioxidant food supplement associated with probiotics on the oocyte quality response, oxidative stress and microbiota function in an in vitro fertilization cycle in patients with…
- Trial name
- NCT04670393
- Testing
- FertyBiotic Woman Plus
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fertypharm
Subfertility
Effect of a Higher Than Maximum 450IU Gonadotropin Dose in an In-vitro Fertilization Cycle
This goal of this study is to evaluate the outcomes from in vitro fertilization cycles where a 450 IU daily dose of gonadotropins is administered compared to those where a 600 IU daily dose is administered for women who are at…
- Trial name
- NCT00971152
- Testing
- menotropins for injection, urofollitropin for injection
- Where
- Canada
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Clinique Ovo
Infertility
Comparison of Clomiphene Citrate and Gonadotropins in Ovulation Induction Cycles
The purpose of the present study is to analyse prospectively if highly purified hMG compared with increased dose of clomiphene citrate has different outcomes in folliculogenesis in ovulation induction cycles.
- Trial name
- cc versus FSH (NCT00835744)
- Testing
- clomiphene citrate, gonadotropins
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Male
To Study the Effect of Magnetic Activated Sperm Sorting on the Outcome of in Vitro Fertilization-embryo Transplantation
Recent studies have evaluated the use of magnetic-activated sperm sorting (MASS) to reduce apoptotic spermatozoa and improve the outcome of infertile male with assisted reproductive technology (ART).
- Trial name
- MASS (NCT03968367)
- Testing
- Magnetic activated sperm sorting
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Li-jun Ding
Infertility, ART
Comparison of the Live Birth Rate Between the PPOS and the GnRH Antagonist Protocol in Patients Undergoing IVF
A randomized comparison of the live birth rate between the progestin-primed ovarian stimulation protocol and the gonadotrophin releasing hormone antagonist protocol in patients undergoing in vitro fertilization Research question…
- Trial name
- NCT03680053
- Testing
- Duphaston, Cetrorelix
- Where
- China
- Volunteers
- 220 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Invitro Fertilization
Poor Responders Infertile Patients -A Great Clinical Challenge
infertile , poor responders patients who underwent ICSI. The participants were divided into 2 groups according to the starting dose of Gn stimulation. Group I started with 4 ampoules while group II started with 6 ampoules
- Trial name
- NCT03402620
- Testing
- Gonadotropins
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Cairo University
Infertility, Female, Luteinizing Hormone (LH)
Extra Luteinizing Hormone Improve Embryo Quality in IVF Patients With Low LH During Long GnRH-Agonist Treatment
This randomized controlled trial aims to evaluate whether supplementation with exogenous luteinizing hormone (LH) can improve embryo quality in patients undergoing in vitro fertilization (IVF) with a long gonadotropin-releasing…
- Trial name
- ELH-IVF (NCT07128394)
- Testing
- Recombinant Luteinizing Hormone (rLH), Recombinant Follicle-Stimulating Hormone (rFSH), Gonadotropin-Releasing Hormone Agonist (GnRH-a)
- Where
- China
- Volunteers
- 590 people
- Sponsor
- Nanjing University
Infertility
Blastocyst Culture Using Time-lapse in Good Prognosis IVF Patients and Elective Single Embryo Transfer
Choosing the best embryo for transfer has become the major challenge in in vitro fertilization (IVF). Morphology alone is obviously not enough and time-lapse incubation has added embryo development kinetics as another selection…
- Trial name
- NCT01773603
- Testing
- Embryoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Dr. Murat Çetinkaya
Adenomyosis of Uterus, Infertility Assisted Reproductive Technology
Does The Addition Of Letrozole To Ultra-Long GnRH Agonists Help Adenomyosis Patients in ART? The AURA Trial
The AURA Trial seeks to improve fertility treatment for women affected by a condition known as adenomyosis. Adenomyosis often leads to heavy menstrual bleeding, pelvic pain, dyspareunia and can make it more difficult to achieve…
- Trial name
- AURA (NCT06985186)
- Testing
- Ultra-Long GnRH Agonists + Letrozole, Ultra-Long GnRH Agonists
- Where
- Spain
- Volunteers
- 162 people
- Sponsor
- University of Palermo