Clinical trials: Infertility (IVF Patients), open to volunteers
Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer
Correlation Of Clinical Outcomes After Transfer Of Good-Quality Morphology Embryos In Patients With A Favorable Prognosis And Non-Invasive Preimplantation Genetic Testing For Aneuploidy (NiPGT-A) Results
Non-invasive preimplantation genetic testing for aneuploidy (NiPGT-A) is an emerging approach that analyzes embryonic cell-free DNA (cfDNA) released into the spent culture medium (SCM) to assess chromosomal status without…
- Conditions
- Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer, Embryo Diagnosis and Selection
- Trial name
- NCT07700602
- Where
- Vietnam
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
225 IU Versus 300 IU Starting FSH Dose in PPOS for Good-Prognosis Women
This randomized controlled trial will compare two starting doses of follicle-stimulating hormone (FSH), 225 IU and 300 IU, during progestin-primed ovarian stimulation (PPOS) in women undergoing in vitro fertilization (IVF) who…
- Trial name
- FSH-PPOS (NCT07772375)
- Testing
- Follitropin Alfa (Follitrope)
- Where
- Vietnam
- Volunteers
- 380 people
- Sponsor
- Vietnam Military Medical University
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
Quantifying Uterine Elastography in Menstruating Women
This study is aiming to characterize the elasticity of the female reproductive tract including the uterus, cervix and ovary using shear wave elastography at different times during the menstrual cycle and define the standard…
- Trial name
- QUEST (NCT06816381)
- Testing
- Shear wave elastography measurements
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility (IVF Patients)
The Role of hCG in Thawed Embryo Transfer
This prospective randomized trial will assess the relevance, if any, of a corpus luteum induced by hCG in transfers of thawed embryos.
- Trial name
- NCT07004192
- Testing
- HCG injection, No intervention
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Poor Ovarian Reserve, Infertility (IVF Patients)
Drospirenone-Primed Ovarian Stimulation Versus GnRH Antagonist Protocol in Poor Ovarian Responders Undergoing Freeze-All IVF/ICSI
Participants will: Take either drospirenone (a daily pill) or the standard daily injection during their ovarian stimulation cycle, alongside their regular fertility hormone injections Undergo egg retrieval, with all resulting…
- Trial name
- PPOS (NCT07736261)
- Testing
- Drospirenone drug, Cetrorelix 0.25 mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmed Saad
Infertility Assisted Reproductive Technology, Infertility (IVF Patients)
Blastocyst AI Assisted Morphokinetics in ART
The goal of this observational study is to learn if embryo characteristics obtained via the recording of real-time embryo activity via 30-seconds video capture (e.g.: Embryo Morphokinetics) can correlate with known embryo outcome…
- Trial name
- AIM (NCT07611448)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Viable Biosciences
Idiopathic Infertility, Infertility Unexplained
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility
The goal of this clinical trial is to determine whether telomere profiling and other biological aging hallmarks can help identify underlying mechanisms of persistent infertility in women with post-treatment unexplained…
- Conditions
- Idiopathic Infertility, Infertility Unexplained, Infertility (IVF Patients), Infertility Assisted Reproductive Technology
- Trial name
- TECMI (NCT07404969)
- Testing
- 1. Aging Hallmarks Biomarker Profiling (Telomere-Based), 2. Integrative Botanical and Nutraceutical Intervention, 3. Natural Conception or Assisted Reproductive Technologies
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- BEYOND GENOMiX SA, AG, Ltd
Infertility (IVF Patients), Infertility Treatment
Ketorolac Use and Fresh Embryo Transfer Outcomes
Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retrieval for patients planning a fresh embryo transfer (usually done 5 days…
- Conditions
- Infertility (IVF Patients), Infertility Treatment, Post-op Pain, Fresh Embryo Transfer
- Trial name
- NCT07185724
- Testing
- Ketorolac 30 mg IV
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jessica D. Kresowik
Male Infertility, Infertility (IVF Patients)
Male Infertility and Assisted Reproductive Technologies Research Biobank
The objective of this research is to build a biobank of biological male specimens used for diagnostics and treatment of infertility or assisted reproductive technologies (ART).
- Trial name
- MARK (NCT06880302)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility (IVF Patients), Artificial Intelligence (AI)
AI-Driven Model Impact on Patient Engagement in Medically Assisted Reproduction
Infertility is a globally significant medical condition, profoundly impacting individuals and couples both emotionally and physically.
- Trial name
- NCT07087171
- Testing
- Artificial intelligence-Machine learning report with accurate personalized probabilities of having a live birth rate
- Where
- Portugal
- Volunteers
- 774 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility (IVF Patients)
Cleavage-stage Versus Blastocyst-stage Embryo Transfer in IVF Patients With Few Embryos
Infertility affects more than 6 million women the United States and is a major life event that results in a wide range of socio-cultural, emotional, physical and financial problems.
- Trial name
- PRECiSE (NCT06746129)
- Testing
- embryo transfer
- Where
- United States
- Volunteers
- 1,126 people
- Sponsor
- Beth Israel Deaconess Medical Center
Infertility (IVF Patients), BMI
BMI Versus Body Fat Percentage - Which is the Better Predictor of Fertility Outcomes in IVF Cycles?
The goal of this prospective observational cohort study is to evaluate whether body composition measured using bioelectrical impedance analysis (BIA) (including measures of body fat% and visceral fat) serve as a better predictor…
- Conditions
- Infertility (IVF Patients), BMI, Bioelectrical Impedance Analysis, IVF Outcomes
- Trial name
- NCT07765368
- Testing
- Measurement of BIA (Body Fat and Visceral Fat Percentage)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Infertility (IVF Patients)
CircularRNA-microRNA-mRNA Regulatory Axis in IVF
1. Investigate the expression levels of circ-0033392, miR-375, miR-1305, JAK2, and PTEN in follicular fluids of females candidate for IVF. 2.
- Trial name
- IVF (NCT06792266)
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Infertile Women Undergoing IVF or ICSI, Distension by Volumetric Analysis of the Uterus
Comparison of Uterine Distension in Hysterosonography Among Patients Monitored for Infertility
Comparison of differences in distension by volumetric analysis of the uterus before and after distension between groups of infertile and apparently fertile women.
- Trial name
- NCT07170137
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Infertility, Genetic Disease
Follow-up With Preimplantation Genetic Testing Patients
The main purpose of this study is to perform longitudinal evaluations of clinical outcomes and personal perspectives following utilization of preimplantation genetic testing (PGT).
- Conditions
- Infertility, Genetic Disease, IVF
- Trial name
- NCT04477863
- Testing
- Follow-up Interview
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Genomic Prediction Inc.
Infertility, Obesity
Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization.
This is a randomized, controlled clinical trial with a two-sided superiority hypothesis. The study evaluates whether a 12-week pre-treatment with semaglutide prior to ovarian stimulation improves the number of good-quality…
- Trial name
- SEQ (NCT07242534)
- Testing
- Semaglutide, No pre-treatment
- Where
- 5 sites in Spain
- Volunteers
- 62 people
- Sponsor
- Fundacion Dexeus
Recurrent Implantation Failure, Infertility (IVF Patients)
Endometrial Immune Profile in Recurrent Implantation Failure
The goal of this observational study is to learn whether differences in the immune cells of the womb lining (endometrium) help explain why some women do not become pregnant despite several IVF attempts using good-quality embryos…
- Trial name
- NCT07848399
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- King's College London
Endometriosis, Infertility Assisted Reproductive Technology
First Line Surgery or First Line Fertility Treatment Using Assisted Reproductive Technologies in Patients With Advanced Endometriosis
Endometriosis is a chronic disease affecting approximately 10% of women of reproductive age. It is strongly associated with pelvic pain and infertility.
- Trial name
- EndoSOFT (NCT07240363)
- Testing
- Endometriosis surgery
- Where
- 4 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Diminished Ovarian Reserve (DOR), Infertility (IVF Patients)
RCT Study on the Effect of ETN on Live Birth Rate in DOR Patients Undergoing IVF-ET
The goal of this clinical trial is to examine the effect of ETN on live birth rate in patients with diminished ovarian reserve (DOR) undergoing in vitro fertilizitaion-embryo transfer (IVF-ET).
- Trial name
- ETN-LBR-DOR (NCT07769684)
- Testing
- electro-thumbtack needle (ETN) / thumbtack needle (TN)
- Where
- 4 sites in China
- Volunteers
- 406 people
- Sponsor
- Huazhong University of Science and Technology
Infertility (IVF Patients)
Triggering Ovulation in Normo-responders Using a Modified Dual Trigger Protocol or HCG Trigger
The aim of this randomized controlled study is to compare the efficacy of a modified dual trigger protocol [a single bolos of HCG combined with two successive doses of a GnRH agonist ] with HCG [a single bolos administered 36…
- Trial name
- NCT07569302
- Testing
- Modified dual trigger, HCG
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Bedaya Hospital