Clinical trials: Infertility Primary, open to volunteers
Being Diagnosed With Primary Infertility, Having Had an Embryo Transfer for the First Time
Effects of Virtual Reality Glasses and Meditation Music on Anxiety, Pain, Vital Signs, Satisfaction and Pregnancy Outcomes in Embryo Transfer Procedure
The aim of this study is to determine the effects of virtual reality glasses (VRG) and meditation music on anxiety, pain, vital signs, satisfaction and pregnancy outcomes during the embryo transfer (ET) procedure.
- Trial name
- NCT06802692
- Testing
- VR glasses and meditation music group, Meditation music group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Nuh Naci Yazgan University
Primary Ovarian Insufficiency, Azoospermia
Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)
Background: Infertility affects 1 in 6 people. Often, the causes of infertility are unknown. Treatments are successful in only about 50% of cases.
- Conditions
- Primary Ovarian Insufficiency, Azoospermia, Oligospermia
- Trial name
- NCT07357701
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Second Cancer, Survivorship
The Prospective Observational COMPRAYA Cohort Study
Rationale: Childhood cancer survivorship attracts attention globally, because successes in treatment have led to increasing number of survivors who reach adulthood, in which survivorship issues affecting health-related quality of…
- Conditions
- Second Cancer, Survivorship, Fertility Issues, Distress, Emotional
- Trial name
- COMPRAYA (NCT04682470)
- Testing
- No intervention ; observational
- Where
- Netherlands
- Volunteers
- 4,000 people
- Sponsor
- The Netherlands Cancer Institute
Ovarian Failure, Ovarian Insufficiency
Ovarian Tissue Allo-transplantation
Premature ovarian failure, also known as primary ovarian insufficiency (POI), or premature menopause, affects 1-2% of women under 40.
- Conditions
- Ovarian Failure, Ovarian Insufficiency, Menopause Ovarian Failure, Menopause, Premature
- Trial name
- NCT06673004
- Testing
- Ovarian tissue allo-transplantation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Gonadal Dysfunction, Gonadal Failure
Fertility Enhancement Through Regenerative Treatment in Ovaries and Testes
This study investigates the safety and efficacy of stem cell or stem cell-derived exosome therapy for gonadal failure, including testicular failure, hypogonadism, ovarian insufficiency, and premature ovarian failure (POF).
- Conditions
- Gonadal Dysfunction, Gonadal Failure, Azoospermia, Testosterone Deficiency
- Trial name
- FERTILE (NCT06841328)
- Testing
- Stem cells
- Where
- United Arab Emirates
- Volunteers
- 60 people
- Sponsor
- Jumeirah American Clinic
Metabolic Diseases, Infertility
Study to Create Potential Cell-Based Therapies to Treat Human Disease and Disability
This is a research study in which your cells will be used for somatic cell nuclear transfer (SCNT), and/or genetic reprogramming research which may result in the production of stem cell lines.
- Trial name
- NCT00628199
- Testing
- Improving the scientific process of human cell reprogramming
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cystic Fibrosis, Congenital Bilateral Absence of Vas Deferens
Establishment of a Primary Epididymal Cell Model From Epididymal Samples to Study CFTR Gene Regulation
The aim of this observational study is to better understand the role and involvement of the regulatory elements of the CFTR gene, with the aim of better describing the 3D organisation of chromatin at the CFTR locus in epididymal…
- Conditions
- Cystic Fibrosis, Congenital Bilateral Absence of Vas Deferens, Sterility, Male
- Trial name
- CFTR-EP (NCT06045702)
- Testing
- Epididymal sample
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Infertility, Artificial Intelligence (AI)
Infertility Treatment
The primary objective of this project is to increase the treatment compliance and success of infertile couples based on the Knowledge-Motivation-Behavioral Skills model.
- Trial name
- ınfertilitech (NCT06960551)
- Testing
- ınfertility group, control group
- Volunteers
- 148 people
- Sponsor
- Inonu University
Recurrent Implantation Failure
ERA in Young Primary Infertile RIF Patients
This study aims to evaluate the clinical efficacy of transcriptome-based endometrial receptivity analysis (tb-ERA) and investigate the molecular mechanisms of abnormal receptivity in young women with unexplained recurrent…
- Trial name
- ERA (NCT07767240)
- Testing
- tb-ERA and personalized embryo transfer
- Where
- China
- Volunteers
- 400 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility Primary
The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF
The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.
- Trial name
- NiOS (NCT06521372)
- Testing
- Magenta AI image analysis tool
- Where
- 3 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Infertility, Female, Polycystic Ovary Syndrome
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, Insulin Resistance, Primary Ovarian Insufficiency
- Trial name
- POMODORI (NCT06167135)
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Infertility, Health Education
Health Education for Women With Suspeced Infertility Waiting for Specialized Care
Introduction: Infertility is defined as a couple's inability to achieve pregnancy after 12 months or more of regular unprotected intercourse. In Brazil, it affects around eight million people.
- Conditions
- Infertility, Health Education, Telemedicine, Telehealth
- Trial name
- NCT06979063
- Testing
- Remote Infertility Education and Counseling, Standard Care Arm
- Where
- Brazil
- Volunteers
- 206 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hysteroscopy
Verbal Analgesia Versus Standard Care for Pain Control in Women With Primary Infertility Undergoing Office Hysteroscopy
Office hysteroscopy is a cornerstone in the diagnostic evaluation of infertile women, enabling direct visualization of the uterine cavity for identifying intrauterine pathology.
- Trial name
- NCT07325994
- Testing
- verbal analgesia, standard care
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Cairo University
Infertility, Female
Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in Women With Primary Infertility
We aim to assess the Safety and Efficacy of Cervical Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in women with primary infertility
- Trial name
- NCT06769204
- Testing
- EMLA SPRAY
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pain
Effect of Music in Reducing Pain and Anxiety During Hysterosalpingography in Women With Primary Infertility
This study aims to demonstrate the value of music in lowering pain and anxiety during hysterosalpingography in women with primary infertility
- Trial name
- NCT06772636
- Testing
- music group, non music group
- Volunteers
- 110 people
- Sponsor
- Cairo University
Anti-Müllerian Hormone, Polycystic Ovarian Syndrome
Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements
This study aims to assess the association of Anti-Müllerian hormone (AMH) with polycystic ovarian syndrome, premature ovarian insufficiency and fertility. The main objectives include the following: 1.
- Conditions
- Anti-Müllerian Hormone, Polycystic Ovarian Syndrome, Premature Ovarian Insufficiency, Fertility Issues
- Trial name
- NCT05858307
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Chinese University of Hong Kong
Infertility, Female, Premature Ovarian Failure
Is There A Role For Mechanical Stimulation In Ovarian Follicular Activation?
Premature ovarian failure (POI) is a loss of normal function before age 40, leading to infertility and hypoestrogenism. About 1% of women younger than 40 years old and 0.1% before 30 are affected.
- Conditions
- Infertility, Female, Premature Ovarian Failure, IVF
- Trial name
- NCT04390308
- Testing
- Ovarian puncture, Hormonal blood Test, Transvaginal ultrasound
- Where
- United Arab Emirates
- Volunteers
- 70 people
- Sponsor
- ART Fertility Clinics LLC
Infertility, Female Infertility
Progesterone Luteal Support in Unexplained Infertility Management
The purpose of this study is to evaluate whether progesterone in women with unexplained infertility can increases live birth rate.
- Conditions
- Infertility, Female Infertility, Subfertility, Infertility Primary
- Trial name
- PLUIM (NCT07738068)
- Testing
- Utrogestan® 200 mg Soft Capsule
- Volunteers
- 640 people
- Sponsor
- Simone Broer