Clinical trials: Infertility and Miscarriage, active
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss
Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction
A low plasma level of mannose binding lectin (p-MBL) is associated with unexplained recurrent pregnancy loss (RPL), but it is not investigated if it is associated with unexplained reproductive failure in general, including…
- Conditions
- Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss, Recurrent Implantation Failure, Infertility
- Trial name
- NCT05169541
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aalborg University Hospital
Infertility, Miscarriage, Recurrent
ANXA5 M2 Haplotyping in IVF Patients and Embryos
This study aims to characterize the association between history of pregnancy complications and M2 carrier status in IVF patients and the utility of M2 haplotype preimplantation genetic testing (PGT) in embryos produced by carrier…
- Conditions
- Infertility, Miscarriage, Recurrent, Pregnancy Complications
- Trial name
- NCT04544462
- Testing
- M2 Test
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Genomic Prediction Inc.
Infertility and Miscarriage
A Multicenter, Prospective, Randomized, Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on the Natural Pregnancy Outcomes in Patients With Non-recurrent Spontaneous Abortion
The study aims to compare the effects of transcervical resection of septa (TCRS) and expectant management on the natural pregnancy outcomes of patients with septate uterus without recurrent abortion, also covering the treatment…
- Trial name
- NCT07039097
- Testing
- Transcervical resection of septum
- Where
- China
- Volunteers
- 418 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Infertility, Female, Recurrent Miscarriage
Immune Cell Populations in the Endometrium
Specialized immunological studies in the diagnostics of idiopathic infertility and recurrent miscarriages have limited applicability, as the role of the immune system in these conditions is not thoroughly understood.
- Conditions
- Infertility, Female, Recurrent Miscarriage, Gynecologic Disease
- Trial name
- NCT06826365
- Testing
- Percentage distribution of immune system cells in peripheral blood, Percentage distribution of immune system cells in endometrium
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Jagiellonian University
Infertility, Implantation Rate
Hyaluronan-enriched Medium and Euploid Blastocyst Transfers
It has been proposed that enriching transfer media with hyaluronan (EmbryoGlue medium) improves pregnancy outcomes compared with media containing lower concentrations of this molecule.
- Conditions
- Infertility, Implantation Rate, Clinical Pregnancy Rate, Live Birth Rate
- Trial name
- GluePloid (NCT06165367)
- Testing
- EmbryoGlue Medium
- Where
- United Arab Emirates
- Volunteers
- 783 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility, Female, Miscarriage
Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?
This study aims to explore the potential correlation between decreased ovarian reserve and previous history of early miscarriage.
- Conditions
- Infertility, Female, Miscarriage, Miscarriage, Recurrent, IVF
- Trial name
- NCT05969574
- Testing
- Transvaginal ultrasound, Blood test AMH
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 2,059 people
- Sponsor
- ART Fertility Clinics LLC
Recurrent Implantation Failure, Recurrent Pregnancy Loss
Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss
The IMERR study aims to improve understanding of certain causes of infertility related to recurrent implantation failure (RIF) and/or recurrent pregnancy loss (RPL), conditions that affect many women undergoing assisted…
- Conditions
- Recurrent Implantation Failure, Recurrent Pregnancy Loss, Infertility, Female, Endometrial Diseases
- Trial name
- IMERR (NCT07265505)
- Testing
- Endometrial Biopsy, Vaginal Swab, Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility and Miscarriage
A Multicenter, Prospective, Randomized Controlled Clinical Study on the Effect of Hysteroscopic Uterine Septum Resection on IVF-ET Outcomes in Infertile Patients With Non-recurrent Miscarriage
This study aims to evaluate the impact of hysteroscopic transcervical resection of the septum (TCRS) on fertility in infertile women without recurrent miscarriage, primarily assessing its effect on subsequent IVF-ET outcomes.
- Trial name
- NCT07611656
- Testing
- Transcervical resection of septum
- Where
- China
- Volunteers
- 236 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Infertility (IVF Patients), Infertility Treatment
Ketorolac Use and Fresh Embryo Transfer Outcomes
Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retrieval for patients planning a fresh embryo transfer (usually done 5 days…
- Conditions
- Infertility (IVF Patients), Infertility Treatment, Post-op Pain, Fresh Embryo Transfer
- Trial name
- NCT07185724
- Testing
- Ketorolac 30 mg IV
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Jessica D. Kresowik
Assisted Reproductive Technology, Assisted Reproductive Technology Outcomes
Sperm Selection Strategies and Male-Factor Phenotypes in ICSI
This retrospective multicentre observational cohort study evaluates clinical and reproductive outcomes associated with different sperm-selection strategies used during intracytoplasmic sperm injection (ICSI), including…
- Trial name
- ANDRO-ART (NCT07825584)
- Testing
- Conventional ICSI, Hyaluronan-Binding Sperm Selection, ZyMōt
- Where
- 10 sites in Poland
- Volunteers
- 12,561 people
- Sponsor
- Center for Reproductive Medicine Bocian