Clinical trials: Inflamation, open to volunteers
Laryngeal Lesions, Systemic Inflammatory Process
Systemic Inflammatory Markers In Vocal Cord Lesions
The aim of this study is to evaluate the levels of systemic inflammatory markers such as PIV, SII, and NPAR in patients with benign and premalignant laryngeal lesions and to determine the diagnostic accuracy of these values using…
- Trial name
- SILVCL (NCT07626125)
- Testing
- Laryngeal polyps, Laryngeal nodules, Laryngeal cysts
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Antalya Health Sciences University
CAD - Coronary Artery Disease, Inflamation
Effect of Empagliflozin on Inflammation
Empagliflozin is a drug given to lower glucose. It is used in the treatment of diabetes. However, it was shown to improve symptoms and survival of patients who are suffering from heart failure.
- Conditions
- CAD - Coronary Artery Disease, Inflamation, PCI, SGLT 2 Inhibitors
- Trial name
- EMPANTINFLAM (NCT07292909)
- Testing
- Empagliflozin (SGLT2i)
- Where
- Lebanon
- Volunteers
- 100 people
- Sponsor
- Hotel Dieu de France Hospital
Multiple Sclerosis, Periodontitis
Periodontal Health Profile in Multiple Sclerosis Patients
This study aims to evaluate the periodontal status of patients with Multiple Sclerosis (MS) through clinical, microbiological, and biochemical parameters.
- Trial name
- NCT07412431
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Prediabetes, Obesity & Overweight
Human Pilot Study for the Investigation of the Role of Bilberry and Olive Bioactives on Oxidative Stress Parameters and Inflammatory Markers.
Numerous plant-based foods contain bioactive compounds, in particular polyphenols, which have antioxidant, anti-inflammatory, and metabolic regulatory effects.
- Conditions
- Prediabetes, Obesity & Overweight, Inflamation, Oxidative Stress
- Trial name
- BIOTRANSFORM (NCT07659028)
- Testing
- supplementation, food
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Stress (Psychology), Inflamation
A Mindfulness-Based Intervention to Reduce Stress Through the Cultivation of Loving-Kindness, Compassion, Joy, and Equanimity in Healthcare Professionals
Nearly 50% of the adult workforce experience adverse psychological symptoms (e.g., stress, depression, burnout, etc.) stemming from workplace stressors, with healthcare workers experiencing rates as high as 80%.
- Conditions
- Stress (Psychology), Inflamation, Psychosocial Functioning
- Trial name
- FIERCE (NCT07283744)
- Testing
- Building Emotional Strength Training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obesity & Overweight, Insulin Resistance
Effects of Exercise Sequence and Meal Sequence on Weight Management Among Children and Adolescents With Overweight or Obesity: The STEP Trial
The goal of this clinical trial is to learn how the order of exercise and the order of eating food affect weight management in overweight and obese children and adolescents.
- Conditions
- Obesity & Overweight, Insulin Resistance, Inflamation
- Trial name
- NCT07712068
- Testing
- Carbohydrate-last eating, Sequential training
- Where
- 9 sites in China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Peking University
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Healthy Adults
Statins Against Bushfire Smoke
The goal of this clinical trial is to test whether statins can protect the heart and brain from the biological stress and inflammatory responses caused by breathing bushfire smoke in healthy adult volunteers aged 18-64 years.
- Trial name
- SABS (NCT07462715)
- Testing
- Atorvastatin
- Where
- Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Menzies Institute for Medical Research
Gut -Microbiota, Inflamation
Impact of a Cricket and Black Soldier Fly Larvae-Fortified Cracker on the Gut Microbiome and Iron Status in Malagasy Schoolchildren
The purpose of this study is to determine the health impacts of consistent consumption of insect-fortified crackers among school-aged children in Madagascar.
- Conditions
- Gut -Microbiota, Inflamation, Iron Absorption
- Trial name
- NCT07439185
- Testing
- Cricket and Black Soldier Fly Larvae-fortified Cracker, Rice and Corn Cracker
- Where
- Madagascar
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Cornell University
Inflamation, Healing
Evaluation of Irisin Levels in Adult Forearm Fracture Surgery Under Infraclavicular Block and General Anesthesia
This randomized prospective study evaluates the effect of general anesthesia versus infraclavicular nerve block on perioperative serum irisin levels in adults undergoing forearm fracture surgery.
- Conditions
- Inflamation, Healing, Angiogenesis
- Trial name
- NCT07324681
- Testing
- General Anesthesia (GA), Infraclavicular Brachial Plexus Blocks
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Patellofemoral Osteoarthritis, Knee Osteoarthritis
FDG PET/MRI Imaging of Patellofemoral Joint Osteoarthritis
This project aims to develop an [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET) / magnetic resonance imaging (MRI) method to locate the painful inflammation in PFJ OA associated with joint loading.
- Conditions
- Patellofemoral Osteoarthritis, Knee Osteoarthritis, Knee Pain, Inflamation
- Trial name
- FDG-PFJOA (NCT07625150)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Inflamation, COPD
Inflammation and Oxidative Stress in COPD
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide, characterized by persistent airflow limitation, chronic inflammation, and increased oxidative stress.
- Conditions
- Inflamation, COPD, Oxidative Stress, Pulmonary Rehabilitation
- Trial name
- NCT07376161
- Testing
- Pulmonary Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Esra Yazar
Primary Stability of the Implants, Pain
Osteoimplant and Dental Implants Stability
Based on the scientific evidence, the relevance of this subject, we consider this study to be justified, the general or specific objective of which is as follows: 'To evaluate the effect of the administration of Osteoimplant© and…
- Trial name
- OIMP (NCT06657521)
- Testing
- osteoimplant
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Chronic Kidney Disease (Stage 3-4)
Effects of Maqui Supplementation on Gut Microbiota, Inflammation, and Oxidative Stress in Patients With Chronic Kidney Disease
Chronic kidney disease (CKD) is a highly prevalent condition in Chile and worldwide and is associated with a substantial burden of morbidity, particularly cardiovascular morbidity.
- Trial name
- maquibiota (NCT07776925)
- Testing
- maqui supplementation, PLA
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad Mayor
Psychopathology, Child Mental Health
Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function
Growing up in a lower-income family robustly predicts worse mental health in adolescence and early adulthood. How does variability in family income "get under the skin" of the developing child and via what mechanisms does it…
- Conditions
- Psychopathology, Child Mental Health, Anxiety Disorders, Mental Disorders
- Trial name
- NCT07641244
- Testing
- Psychological fMRI task
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Northwestern University
Diabete Mellitus, Diabete Type 2
Inflammation and Diabetes: Evaluating Antioxidant Levels
The goal of this observational, cross-sectional study is to evaluate the relationships between dietary total antioxidant capacity, systemic inflammatory response markers, and nutritional parameters in adult patients with Type 2…
- Conditions
- Diabete Mellitus, Diabete Type 2, Inflamation, Systemic Inflammation
- Trial name
- IDEAL (NCT07734428)
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Istanbul Bilgi University
Peri-implantitis, Soft Tissue Augmentation at Dental Implants
Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
This study aims to increase the width and thickness of peri-implant keratinized mucosa (KM) by transferring a properly dimensioned free gingival graft (FGG) from the palatal donor site and to evaluate its effect as an adjunctive…
- Trial name
- NCT07471386
- Testing
- Submucosal debridman + saline irrigation, Free gingival graft surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Metabolic Syndrome, Diabetes
EFFECTS OF A YERBA MATE EXTRACT IN REDUCING METABOLIC SYNDROME IN OVERWEIGHT INDIVIDUALS
Yerba mate (Ilex paraguariensis), a traditional drink consumed in different parts of the word, but especially in southern Brazil, is an importante source of polyphenols and has a high antioxidant potencial, With a moderate…
- Conditions
- Metabolic Syndrome, Diabetes, Oxidative Stress, Dyslipidemia
- Trial name
- NCT07000825
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Federal da Fronteira Sul
Endothelial Function, Oxidative Stress
Black Forest Cocoa Flavanol Supplementation and Health Trial
This randomized, double-blind, controlled clinical trial will evaluate the effects of daily cocoa flavanol supplementation on vascular and inflammatory biomarkers in healthy adult men aged 30 to 75 years.
- Conditions
- Endothelial Function, Oxidative Stress, Inflamation, Vascular Health
- Trial name
- NCT07747714
- Testing
- Cocoa Flavanol Supplement, Low-Flavanol Control Powder
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Black Forest LLC
Type 2 Diabetes Mellitus (T2DM), Insulin Resistance
Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise
The study evaluates the impact of a strict vegetarian diet combined with regular physical exercise and the use of probiotics on metabolic, inflammatory, and epigenetic parameters in patients with type 2 diabetes.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Insulin Resistance, Inflamation, Gut Microbiomes
- Trial name
- NCT06959043
- Testing
- Probiotic Supplementation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Maria Elizabeth Rossi da Silva