Clinical trials: Inflamation, active
Geriatric Anesthesia, Postop Adult ICU Patients
Systemic Immun Inflamation Score Corelation in Postoperative Patients Prognosis
The Systemic Immuno-Inflammation Index (SII) is a ratio derived from complete blood count parameters (neutrophils, lymphocytes, platelets) and is a non-invasive and easily calculable biomarker.
- Trial name
- NCT07544719
- Volunteers
- 150 people
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Stress (Psychology), Inflamation
A Mindfulness-Based Intervention to Reduce Stress Through the Cultivation of Loving-Kindness, Compassion, Joy, and Equanimity in Healthcare Professionals
Nearly 50% of the adult workforce experience adverse psychological symptoms (e.g., stress, depression, burnout, etc.) stemming from workplace stressors, with healthcare workers experiencing rates as high as 80%.
- Conditions
- Stress (Psychology), Inflamation, Psychosocial Functioning
- Trial name
- FIERCE (NCT07283744)
- Testing
- Building Emotional Strength Training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Laryngeal Lesions, Systemic Inflammatory Process
Systemic Inflammatory Markers In Vocal Cord Lesions
The aim of this study is to evaluate the levels of systemic inflammatory markers such as PIV, SII, and NPAR in patients with benign and premalignant laryngeal lesions and to determine the diagnostic accuracy of these values using…
- Trial name
- SILVCL (NCT07626125)
- Testing
- Laryngeal polyps, Laryngeal nodules, Laryngeal cysts
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Antalya Health Sciences University
Radiotherapy, Inflamation
Effects of Moderate-intensity Interval Aerobic Exercise (MIIAE) on Inflammatory, Immune, Metabolic, Physical Fitness, and Quality of Life Parameters in Breast Cancer Patients Undergoing Radiotherapy.
Breast cancer and its treatment with radiotherapy may be associated with systemic inflammatory, hematological, cardiac, body composition, functional and quality-of-life alterations.
- Conditions
- Radiotherapy, Inflamation, Immune System, Physical Fitness
- Trial name
- NCT07583719
- Testing
- Moderate-Intensity Interval Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria
Multiple Sclerosis, Periodontitis
Periodontal Health Profile in Multiple Sclerosis Patients
This study aims to evaluate the periodontal status of patients with Multiple Sclerosis (MS) through clinical, microbiological, and biochemical parameters.
- Trial name
- NCT07412431
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Bariatric Surgery, Bariatric Sleeve Gastrectomy
Effects of the Dietary Inflammatory Index on Systemic Inflammation Markers and Gastrointestinal Symptoms in Individuals With Bariatric Surgery
The goal of this observational cross-sectional study is to evaluate the relationships between the Dietary Inflammatory Index (DII), systemic inflammatory markers, and gastrointestinal symptoms in adults aged 18-65 who have…
- Conditions
- Bariatric Surgery, Bariatric Sleeve Gastrectomy, Inflamation, Systemic Inflammation
- Trial name
- NCT07293624
- Testing
- Observational Intervention, Observetional
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Bilgi University
Critical Illness, Geriatric Patient
Dynamic Inflammatory Changes and Nutritional Risk Scores in ICU Patients Aged 65 Years and Older
"This prospective observational study aims to evaluate the prognostic value of dynamic changes in the serum uric acid-to-albumin ratio (UAR) measured on admission (Day 0) and on Day 3, along with mNUTRIC and PNI scores, regarding…
- Conditions
- Critical Illness, Geriatric Patient, Mortality, Inflamation
- Trial name
- NCT07888010
- Testing
- Uric Acid to Albumin Ratio (UAR) and Nutritional Risk Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 224 people
- Sponsor
- Ankara Etlik City Hospital
Patellofemoral Osteoarthritis, Knee Osteoarthritis
FDG PET/MRI Imaging of Patellofemoral Joint Osteoarthritis
This project aims to develop an [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET) / magnetic resonance imaging (MRI) method to locate the painful inflammation in PFJ OA associated with joint loading.
- Conditions
- Patellofemoral Osteoarthritis, Knee Osteoarthritis, Knee Pain, Inflamation
- Trial name
- FDG-PFJOA (NCT07625150)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis. Objectives : 1.
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant
- Trial name
- NCT07089381
- Testing
- Resveratrol 1 gm., Methotrexate
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Inflamation, Hemodialysis
Effect of Sertraline on Inflammation in Hemodialysis Patients with Depression: a Randomized Controlled Trial
Depression is a common mental health condition among patients undergoing hemodialysis and is associated with a lower quality of life, poor treatment adherence, and worse overall health outcomes.
- Conditions
- Inflamation, Hemodialysis, End Stage Renal Disease on Hemodialysis (Diagnosis)
- Trial name
- NCT06840379
- Testing
- Sertraline (Oral Antidepressant)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Nishtar Medical University
Type 2 Diabetes Mellitus (T2DM), Insulin Resistance
Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise
The study evaluates the impact of a strict vegetarian diet combined with regular physical exercise and the use of probiotics on metabolic, inflammatory, and epigenetic parameters in patients with type 2 diabetes.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Insulin Resistance, Inflamation, Gut Microbiomes
- Trial name
- NCT06959043
- Testing
- Probiotic Supplementation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Maria Elizabeth Rossi da Silva
Inflamation, Healing
Evaluation of Irisin Levels in Adult Forearm Fracture Surgery Under Infraclavicular Block and General Anesthesia
This randomized prospective study evaluates the effect of general anesthesia versus infraclavicular nerve block on perioperative serum irisin levels in adults undergoing forearm fracture surgery.
- Conditions
- Inflamation, Healing, Angiogenesis
- Trial name
- NCT07324681
- Testing
- General Anesthesia (GA), Infraclavicular Brachial Plexus Blocks
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Peri-implantitis, Soft Tissue Augmentation at Dental Implants
Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
This study aims to increase the width and thickness of peri-implant keratinized mucosa (KM) by transferring a properly dimensioned free gingival graft (FGG) from the palatal donor site and to evaluate its effect as an adjunctive…
- Trial name
- NCT07471386
- Testing
- Submucosal debridman + saline irrigation, Free gingival graft surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Healthy Adults
Statins Against Bushfire Smoke
The goal of this clinical trial is to test whether statins can protect the heart and brain from the biological stress and inflammatory responses caused by breathing bushfire smoke in healthy adult volunteers aged 18-64 years.
- Trial name
- SABS (NCT07462715)
- Testing
- Atorvastatin
- Where
- Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Menzies Institute for Medical Research
Diabete Mellitus, Diabete Type 2
Inflammation and Diabetes: Evaluating Antioxidant Levels
The goal of this observational, cross-sectional study is to evaluate the relationships between dietary total antioxidant capacity, systemic inflammatory response markers, and nutritional parameters in adult patients with Type 2…
- Conditions
- Diabete Mellitus, Diabete Type 2, Inflamation, Systemic Inflammation
- Trial name
- IDEAL (NCT07734428)
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Istanbul Bilgi University
Cardiovascular (CV) Risk, Atheroscleroses
Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower Oils
This randomized, single-blind, crossover clinical trial aims to evaluate Echium oil and Ahiflower® oil as sustainable, plant-based alternatives to marine oils for omega-3 supplementation.
- Conditions
- Cardiovascular (CV) Risk, Atheroscleroses, Inflamation, Omega 3 Fatty Acids
- Trial name
- NCT07289919
- Testing
- Echium oil, Ahiflower oil, EPA capsules
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gut -Microbiota, Inflamation
Impact of a Cricket and Black Soldier Fly Larvae-Fortified Cracker on the Gut Microbiome and Iron Status in Malagasy Schoolchildren
The purpose of this study is to determine the health impacts of consistent consumption of insect-fortified crackers among school-aged children in Madagascar.
- Conditions
- Gut -Microbiota, Inflamation, Iron Absorption
- Trial name
- NCT07439185
- Testing
- Cricket and Black Soldier Fly Larvae-fortified Cracker, Rice and Corn Cracker
- Where
- Madagascar
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Cornell University
Psychopathology, Child Mental Health
Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function
Growing up in a lower-income family robustly predicts worse mental health in adolescence and early adulthood. How does variability in family income "get under the skin" of the developing child and via what mechanisms does it…
- Conditions
- Psychopathology, Child Mental Health, Anxiety Disorders, Mental Disorders
- Trial name
- NCT07641244
- Testing
- Psychological fMRI task
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Northwestern University
Endothelial Function, Oxidative Stress
Black Forest Cocoa Flavanol Supplementation and Health Trial
This randomized, double-blind, controlled clinical trial will evaluate the effects of daily cocoa flavanol supplementation on vascular and inflammatory biomarkers in healthy adult men aged 30 to 75 years.
- Conditions
- Endothelial Function, Oxidative Stress, Inflamation, Vascular Health
- Trial name
- NCT07747714
- Testing
- Cocoa Flavanol Supplement, Low-Flavanol Control Powder
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Black Forest LLC
Familiar Hypercholesterolemia
High Intensity Interval Training in the Treatment of Familial Hypercholesterolemia (UPPA-FH)
This study has one main objective: a) To assess the impact of two different supervised exercise interventions on cardiorespiratory fitness and markers of subclinical atherosclerosis in patients with Familiar Hipercolesterolemia…
- Trial name
- UPPA-FH (NCT06833944)
- Testing
- HIIT intervention program, MICT intervention program
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental